Cochrane

Review question: Cochrane review authors investigated different regimens used for preparing the uterus (womb) for transferring frozen-thawed embryos to the uterus in women undergoing assisted reproductive technology (ART) to become pregnant. Background In subfertile women undergoing ART, eggs are collected from the ovaries and fertilised by sperm ...

Background This is an updated version of an original Cochrane review published in Issue 6, 2014. Pelvic lymphadenectomy (removal of lymph glands found in the pelvis) is an important component of the surgical management of gynaecological cancers to see if the cancer has spread. However, it can lead to complications, especially lymphocyst formation (collection ...

Protocol: We aim to assess the comparative effectiveness and/or safety of interventions currently being used to treat couples with unexplained subfertility.

Protocol: This review has two objectives. These are: to assess the comparative effectiveness (pregnancy and live birth) and safety (ovarian hyperstimulation syndrome) in women undergoing in vitro fertilisation/intracytoplasmic sperm injection (IVF/ICSI): of different doses of gonadotropin in women subgrouped by their expected response to stimulation, ...

Review question Are antibiotics effective and safe for preventing postoperative infection in women undergoing elective (non-urgent) hysterectomy? Background Surgical operation carried out to remove the uterus (hysterectomy) is commonly performed. Most cases are performed as non-urgent (elective) procedures for non-cancerous (benign) conditions affecting ...

Review question The aim of this review was to assess whether pretreatment with a combined oral contraceptive pill (COCP) or with progestogen or oestrogen alone influences pregnancy outcomes in couples with low fertility undergoing assisted reproductive technology (ART) Background In vitro fertilisation (IVF; where an egg is mixed with sperm outside ...

Review question What is the effectiveness and safety of a combination of recombinant luteinizing hormone (rLH) and recombinant follicle-stimulating hormone (rFSH) compared to rFSH alone for ovarian stimulation in women undergoing in-vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI)? Background In natural ovarian cycles, luteinizing ...

Review question To assess the effect of withholding gonadotrophins (coasting) to prevent ovarian hyperstimulation syndrome in assisted reproduction cycles. Background Ovarian hyperstimulation syndrome (OHSS) is a complication of using hormones to induce ovulation (the release of eggs) in IVF (in vitro fertilization). The hormones can sometimes over ...

Review question Cochrane researchers reviewed the evidence about the effectiveness of metabolomics as an evaluation tool to improve the rates of ongoing pregnancy, live birth, and miscarriage in women who were undergoing assisted reproductive technology (ART). Background Metabolomics is the scientific study of the chemical 'fingerprints' that biological ...

Protocol: To assess the effectiveness and safety of the levonorgestrel intrauterine system (LNG-IUS) for treatment of endometrial hyperplasia (EH) with or without atypia.