Cochrane

Review question We reviewed the evidence for the effectiveness and safety of statins in children with inherited high blood cholesterol. Background Familial hypercholesterolemia is an inherited disease in which the blood cholesterol level is high. Vascular disease, i.e. furring up of the blood vessels, often occurs at an earlier age than usual, especially ...

Review question Phototherapy is a pain-free method of treatment that uses light to treat various medical conditions. We reviewed the evidence about phototherapy for foot ulcers in people with diabetes. We wanted to find out whether phototherapy speeds up wound healing and improves patients' quality of life, and whether there are any side effects. Background Foot ...

Review question How effective are diet, physical activity and behavioural interventions in reducing the weight of overweight or obese children aged 6 to 11 years? Background Across the world more children are becoming overweight and obese. These children are more likely to suffer from health problems, both while as children and in later life. More ...

Review question How effective are diet, physical activity and behavioural interventions in reducing the weight of overweight or obese adolescents aged 12 to 17 years? Background Across the world, more adolescents are becoming overweight and obese. These adolescents are more likely to suffer from health problems in later life. More information is ...

What is the aim of this review? The aim of this Cochrane Review was to find out which is the best type of anti-VEGF drug for diabetic macular oedema (DMO). Cochrane researchers collected and analysed all relevant studies to answer this question and found 24 studies. Key messages Anti-VEGF drugs given by injection into the eye improve vision in people ...

Review question We reviewed the evidence about whether or not antimicrobial agents (antibacterial products) can prevent or treat foot infections in people with diabetes when they are applied topically (directly to the affected area). We wanted to find out if antibacterial treatments could help both infected and uninfected wounds to heal, and prevent ...

What is the issue? If a mother already has diabetes when she becomes pregnant, she and her baby are at a higher risk of various problems in pregnancy, labour, birth and later. During pregnancy, the mother will have her blood glucose levels (sometimes referred to as blood sugar levels) monitored so appropriate steps can be taken to control her blood ...

What is the issue? In many parts of the world, diabetes is the most common reason that people experience kidney failure and need treatment with a kidney transplant or dialysis. Disability (blindness, limb loss, kidney failure) due to diabetes is caused by high blood glucose (sugar) levels. An important question is whether extra treatment to control ...

Protocol: To assess whether intermediate hyperglycaemia is a predictor for the development of type 2 diabetes mellitus (T2DM).

Review question Are the glucose-lowering medicines, DPP-4 inhibitors (e.g. linagliptin or vildagliptin) and GLP-1 analogues (e.g. exenatide or liraglutide) able to prevent or delay the development of type 2 diabetes and its associated complications in people at risk for the development of type 2 diabetes? Background DPP-4 inhibitors and GLP-1 analogues ...