Cochrane

Background Despite many antiepileptic drugs being available, about 30% of epilepsy patients are not seizure-free. Electrical stimulation through implanted electrodes in contact with the brain (i.e. intracranial electrical stimulation, referring to 'deep brain stimulation' and 'cortical brain stimulation') has been proposed as an alternative treatment ...

What is the issue? In the past, women have been cared for and supported by other women during labour and birth, and have had someone with them throughout, which we call ‘continuous support’. However, in many countries more women are giving birth in hospital rather than at home. This has meant continuous support during labour has become the exception ...

Review question: Does administering lactoferrin with feeds decrease the risk of sepsis or necrotizing enterocolitis in preterm babies? Background: Preterm babies are at risk for blood infection (sepsis) and/or gastrointestinal injury (necrotizing enterocolitis, or NEC). Many babies with sepsis or NEC die or develop long-term brain and lung injury ...

Review question Is there trial-based evidence that a traditional Chinese herbal medicine, Wendan decoction (WDD) is effective for treatment of people with schizophrenia? Background Schizophrenia is a severe mental illness, characterised by profound disruptions in thinking that affects language, perception, and sense of self. People with schizophrenia ...

Review question Is repetitive peripheral magnetic stimulation (rPMS) effective for improving everyday activities in people after stroke? Background Stroke, the most common cause of disability, occurs when a blood clot blocks a blood vessel in the brain. Two types of stroke are known: ischaemic, due to lack of blood flow, and haemorrhagic, due to bleeding. ...

Protocol: To evaluate the effectiveness and tolerability of dietary intervention with the ketogenic diet (KD) for the management of brain and spinal cord tumours, including the effect on brain-tumour related epilepsy.

Protocol: The primary aim of this study is to investigate the effects of exercise training on exercise capacity in adults with advanced lung cancer. Exercise capacity is defined as the Six-Minute Walk Distance (6MWD; in meters) measured during a 6MWT (i.e. how far an individual can walk in 6 minutes on a flat course) or the peak oxygen uptake ...

Review Question What are the effects of providing music therapy or adding music therapy to treatment for people with schizophrenia or schizophrenia-like disorders? Background Characteristics of schizophrenia and schizophrenia-like disorders are disordered thoughts, feelings, beliefs and perceptions. People with schizophrenia often have two main ...

Protocol: To assess the effectiveness and safety of yoga for treatment of urinary incontinence in women, compared to no specific treatment, to another active treatment, or to an active treatment without adjuvant yoga, with a focus on patient symptoms and quality of life.

Background Hepatic encephalopathy is a brain dysfunction associated with liver disease. Cirrhosis, which is a condition where scar tissue (fibrosis) replaces the normal liver tissue, is the most common cause of hepatic encephalopathy. The severity of the symptoms range from minor signs to coma. The minor changes are known as minimal hepatic encephalopathy. ...