Cochrane

What is the aim of this review? The aim of this Cochrane Review was to assess the benefits and harms of drug therapy for chronic idiopathic axonal polyneuropathy (CIAP). Cochrane Review authors collected and aimed to analyse all relevant studies to answer this question. This is the most recent update of a review first published in 2004. Key messages There ...

Neuromuscular Group Saint-Clair Bernardes Neto Title Tuesday, January 10, 2017 ...

Bottom line We found low-quality evidence that oral tramadol has any important beneficial effect on pain in people with moderate or severe neuropathic pain. There is very little evidence from which to take these conclusions. Background Neuropathic pain is pain coming spontaneously or abnormally from damaged nerves. It is different from pain messages ...

Bottom line There is moderate-quality evidence that oral gabapentin at doses of 1200 mg daily or more has an important effect on pain in some people with moderate or severe neuropathic pain after shingles or due to diabetes. Background Neuropathic pain comes from damaged nerves. It is different from pain messages that are carried along healthy nerves ...

Review question We reviewed the evidence for giving people with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) treatment that regulates the immune system other than corticosteroids, immunoglobulin and plasma exchange. Background CIDP is an uncommon disease that causes weakness and numbness of the arms and legs. The condition may ...

Protocol: To assess and compare the effects and complication rates of licensed bioengineered nerve conduits or wraps for surgical repair of traumatic peripheral nerve injuries of the upper limb. To compare effects and complications against the current gold surgical standard (nerve autograft).

Review question We reviewed the evidence about the effect of plasma exchange in people with Guillain-Barré syndrome (GBS). Background GBS is a rare, serious disease in which the peripheral nerves (nerves outside the central nervous system) become inflamed. The condition causes paralysis and sensory disturbance. Many people who develop GBS have had ...

Neuromuscular Group Renata Scalco Title Tuesday, January 17, 2017 ...

Review question What are the effects of treatments to prevent or treat thinning of bones (osteoporosis) and prevent fragile bones from breaking (fragility fractures) in adults and children with Duchenne muscular dystrophy (DMD) who are taking long-term corticosteroids? Background DMD is an inherited condition, affecting about one in 3500 to one ...

Neuromuscular Group Cynthia Ang Title Tuesday, January 10, 2017 ...