Cochrane

Protocol: To determine whether administration of prebiotics reduces the incidence of hyperbilirubinaemia among term and preterm infants compared with enteral supplementation of milk with distilled water or no supplementation.

Review question: Does head midline position reduce the risk of intraventricular hemorrhage (i.e., bleeding in the brain) and mortality in very preterm infants? Background: Intraventricular hemorrhage (i.e., bleeding in the brain) occurs in 25% of very low birth weight infants and may be caused by multiple factors. Head position may affect how the ...

Review question: How does saline irrigation or saline irrigation with prior hyaluronidase compare with no intervention or normal wound care for improving tissue healing in neonates with extravasation injury? Background: Preterm and sick term infants requiring intravenous fluids and medications are vulnerable to tissue injury secondary to extravasation, ...

Review question Does the use of prolonged (or sustained, > 1 second duration) lung inflation rather than standard inflations (≤ 1 second) improve survival and other important outcomes among newly born babies receiving resuscitation at birth? Background At birth, the lungs are filled with fluid, which must be replaced by air for babies to breathe ...

Protocol: To determine effects of non-invasive high-frequency ventilation compared with other forms of respiratory support in newborn infants with respiratory distress in terms of need for intubation or reintubation and morbidity and mortality in term and preterm newborn infants. We will examine use of nHFV in the following situations. Initial ...

Neonatal Group Matteo Bruschettini Title Saturday, July 1, 2017 ...

Neonatal Group Matteo Bruschettini Title Saturday, July 1, 2017 ...

What is the issue? ln about 1 out of every 10 pregnancies, babies are exposed to meconium during delivery. Meconium is the baby's first stool. If the baby passes stool before birth, stool containing amniotic fluid can enter the baby's lungs and may cause breathing difficulty while putting the baby at risk for infection and inflammation in the lungs ...

Review question: Does administering lactoferrin with feeds decrease the risk of sepsis or necrotizing enterocolitis in preterm babies? Background: Preterm babies are at risk for blood infection (sepsis) and/or gastrointestinal injury (necrotizing enterocolitis, or NEC). Many babies with sepsis or NEC die or develop long-term brain and lung injury ...

Protocol: To summarize the evidence from systematic reviews regarding the effects and safety of pharmacological interventions related to pain and sedation management in order to prevent GMH-IVH in ventilated preterm infants.