Cochrane

Hypertension Group James Wright Title Friday, June 16, 2017 ...

Review question We assessed the effect of cocoa products on blood pressure in adults when consumed daily for at least two weeks. We found 35 studies, covering 40 treatment comparisons. Background Dark chocolate and cocoa products are rich in chemical compounds called flavanols. Flavanols have attracted interest as they might help to reduce blood ...

Background Uric acid is the natural end product produced by the breakdown of the body's tissues and a person's food, most notably protein. Uric acid is usually removed from the blood by the kidneys and eliminated from the body in the urine. However, if too much uric acid is produced or the kidneys are not able to remove it from the blood as usual, ...

Review question Studies in which participants were distributed by chance into groups with high and low salt intake were analysed to investigate the effect of reduced salt intake on blood pressure (BP) and potential side effects of sodium reduction on some hormones and lipids. Background As a reduction in salt intake decreases blood pressure (BP) ...

Review Question(s): We wanted to determine if aliskiren was better than placebo for reducing blood pressure in adult patients with raised blood pressure, and whether this drug had increased adverse effects. We also wanted to determine if there was a change in blood pressure variability, pulse pressure, heart rate and withdrawal due to side effects. We ...

Protocol: To analyze the temporal (hourly and 24-hour) blood pressure (BP) lowering efficacy of angiotensin receptor blockers (ARBs).

Review question The aim of this review was to determine the effectiveness of eplerenone for reducing blood pressure, its side effect profile, and its impact on clinically meaningful outcomes such as mortality and morbidity. Background Clinicians have used eplerenone to treat high blood pressure since 2002. It is important to determine the clinical ...

Protocol: To investigate whether withdrawal of antihypertensive medicines is feasible, and evaluate the effects of withdrawal of antihypertensive medicines on mortality, cardiovascular outcomes, hypertension and quality of life in older people.

Protocol: To evaluate the efficacy and safety of renin inhibitors compared to ACE inhibitors in people with primary hypertension.

Protocol: To evaluate the efficacy and safety of renin inhibitors compared to angiotensin receptor blockers in people with primary hypertension.