Cochrane

Drugs and Alcohol Group Miguel Tolosa-Rodriguez Title Sunday, July 16, 2017 ...

Review question We reviewed the evidence on the effects of opioid antagonists (naltrexone, naloxone) plus minimal sedation for managing withdrawal in people who are dependent on opioid drugs (for example, heroin or pharmaceutical opiates). Background Managed withdrawal, or detoxification, is a required first step for longer-term treatments of opioid ...

Review question We reviewed the evidence about the effectiveness of supervised dosing strategies in opioid substitution treatment for people dependent on opioid drugs. Background Opioid dependence (OD) is a global clinical and public health problem that is associated with significant burden of disease and drug-related deaths. OD represents a complex ...

Protocol: Main objective To assess the effects of music therapy, as a primary or a supportive intervention, compared to standard care, wait-list control or no treatment, for people with substance use disorders, to reduce substance use,the severity of substance dependence/abuse, psychological symptoms, and substance craving; to enhance motivation ...

Drugs and Alcohol Group John Kelly Title Thursday, February 23, 2017 ...

Review question We reviewed the evidence about the effect of buprenorphine for managing withdrawal in people who are dependent on opioid drugs (for example, heroin or pharmaceutical opiates). Background Managed withdrawal, or detoxification, is a required first step for long-term treatment of opioid dependence. The combination of uncomfortable symptoms ...

Protocol: To assess the efficacy and safety of baclofen for managing patients with alcohol use disorder.

Review question We reviewed the evidence about the effect of psychosocial treatment, which encompasses a wide variety of strategies that aim to change behaviour and support adults who are affected by harmful use, abuse or dependence on cocaine or amphetamines, including MDMA (ecstasy). Background Globally, cocaine and amphetamines are the two main ...

Review question We investigated whether psychostimulant substitution was safe and effective for treating patients with cocaine dependence. Background Cocaine dependence is a frequent disorder for which no medication has been approved for treatment. Substitution therapy involves the replacement of the abused drug, which is often illegal and used ...

Protocol: To assess the effectiveness of universal, selective and indicated family-based prevention programs in preventing alcohol use, or problem drinking, in school-aged children (up to 18 years of age). Specifically, on these outcomes, the review aims: To assess the effectiveness of universal family-based prevention programs for all children ...