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Oral Health Group (181)
ORAL HEALTH (181)
Dental caries (42)
Prevention (20)
Antimicrobial (2)
Antibacterial agents (1)
Antibacterial agents in composite restorations for the prevention of dental caries
Chlorhexidine (1)
Chlorhexidine interventions for the prevention of caries in adults (protocol stage)
Mouthwashes/rinses (0)
Gel (0)
Dental floss (0)
Interdental brushes/sticks (0)
Irrigators (0)
Preventative therapies (2)
Pit & Fissure sealants (2)
Pit and fissure sealants for preventing dental decay in the permanent teeth of children and adolescents
Pit and fissure sealants versus fluoride varnishes for preventing dental decay in children and adolescents
Fluoride therapy (14)
Topical (11)
Combinations of topical fluoride (toothpastes, mouthrinses, gels, varnishes) versus single topical fluoride for preventing dental caries in children and adolescents
Fluoride gels for preventing dental caries in children and adolescents
Fluoride mouthrinses for preventing dental caries in children and adolescents
Fluoride toothpastes for preventing dental caries in children and adolescents
Fluoride toothpastes of different concentrations for preventing dental caries in children and adolescents (protocol stage)
Fluoride varnishes for preventing dental caries in children and adolescents
Fluorides for the prevention of white spots on teeth during fixed brace treatment
One topical fluoride (toothpastes, or mouthrinses, or gels, or varnishes) versus another for preventing dental caries in children and adolescents
Slow-release fluoride devices for the control of dental decay
Topical fluoride (toothpastes, mouthrinses, gels or varnishes) for preventing dental caries in children and adolescents
Topical fluoride as a cause of dental fluorosis in children (protocol stage)
Systemic (3)
Fluoridated milk for preventing dental caries
Fluoride supplements (tablets, drops, lozenges or chewing gums) for preventing dental caries in children (protocol stage)
Salt fluoridation for preventing dental caries (protocol stage)
Diet (2)
Dietary advice (1)
One-to-one dietary interventions undertaken in a dental setting for a change in dietary behaviour and the prevention of dental caries and erosion (protocol stage)
Infant feeding (0)
Sugar substitutes (1)
Xylitol containing oral products for preventing dental caries (protocol stage)
Oral health education (0)
Treatment (22)
Restorative (11)
Tooth restorations (11)
Adhesively bonded versus non-bonded amalgam restorations for dental caries
Atraumatic restorative treatment versus conventional restorative treatment for the management of dental caries (protocol stage)
Ceramic inlays for restoring posterior teeth
Complete or ultraconservative removal of decayed tissue in unfilled teeth
Dental fillings for the treatment of caries in the primary dentition
Direct composite resin fillings versus amalgam fillings for permanent or adult posterior teeth (protocol stage)
Direct versus indirect veneer restorations for intrinsic dental stains
Preformed metal crowns for decayed primary molar teeth
Replacement versus repair of defective restorations in adults: amalgam (protocol stage)
Replacement versus repair of defective restorations in adults: resin composite (protocol stage)
Root canal posts for the restoration of root filled teeth
Prostheses (0)
Extraction (0)
Postoperative complications (0)
Endodontics (8)
Hand and ultrasonic instrumentation for orthograde root canal treatment of permanent teeth
Magnification devices for endodontic therapy
Materials for retrograde filling in root canal therapy (protocol stage)
Nickel-titanium versus stainless steel instrumentation for orthograde endodontic therapy (protocol stage)
Pulp management for caries in adults: maintaining pulp vitality
Pulp treatment for extensive decay in primary teeth
Single versus multiple visits for endodontic treatment of permanent teeth
Surgical versus non-surgical endodontic re-treatment for periradicular lesions
Fluoride therapy (1)
Topical (1)
Topical fluoride for treating dental caries (protocol stage)
Ozone (1)
Ozone therapy for the treatment of dental caries
Chemo-mechanical treatment (1)
Chemo-mechanical treatment of tooth decay (protocol stage)
Oral hygiene (2)
Interventions for cleaning dentures in adults
One-to-one oral hygiene advice provided in a dental setting for oral health (protocol stage)
Periodontal disease (17)
Gingivitis (0)
Pregnancy gingivitis (0)
Acute ulcerative gingivitis (0)
Prevention (5)
Oral health education (0)
Oral hygiene instruction (1)
Psychological interventions to improve adherence to oral hygiene instructions in adults with periodontal diseases
Antimicrobial (0)
Mouthwashes/rinses (0)
Gels (0)
Toothbrushes (2)
Manual or powered (2)
Manual versus powered toothbrushing for oral health
Powered toothbrushes for oral health (protocol stage)
Dentifrices/toothbrushes (1)
Anti-calculus (0)
Triclosan (1)
Triclosan-containing toothpaste for gingival health (protocol stage)
Dental floss (0)
Interdental brushes/sticks (0)
Irrigators (0)
Psychological interventions (1)
Psychological interventions to improve adherence to oral hygiene instructions in adults with periodontal diseases
Treatment (8)
Surgical (1)
Enamel matrix derivative (Emdogain®) for periodontal tissue regeneration in intrabony defects
Guided tissue regeneration (1)
Guided tissue regeneration for periodontal infra-bony defects
Non-surgical (5)
Full-mouth disinfection for the treatment of adult chronic periodontitis
Interleukin-1 receptor antagonist for treating periodontitis (protocol stage)
Local delivery antimicrobials for chronic periodontitis (protocol stage)
Routine scale and polish for periodontal health in adults
Systemic antibiotics as adjunctive treatment for periodontitis (protocol stage)
Occlusal interventions (1)
Occlusal interventions for periodontitis in adults
Periodonal disease & associated conditions (4)
Alendronate for preventing tooth loss in postmenopausal women (protocol stage)
Root coverage procedures for the treatment of localised recession-type defects
Treating periodontal disease for preventing preterm birth in pregnant women (protocol stage)
Treatment of periodontal disease for glycaemic control in people with diabetes (protocol stage)
Halitosis (2)
Mouthrinses for the treatment of halitosis
Tongue scraping for treating halitosis
Craniofacial anomalies (30)
Treatment (30)
Central giant cell granuloma (1)
Interventions for central giant cell granuloma (CGCG) of the jaws
Orthodontic treatment (25)
Adhesives for fixed orthodontic bands
Adhesives for fixed orthodontic brackets
Enamel etching for bonding fixed orthodontic braces (protocol stage)
Extraction of primary (baby) teeth for unerupted palatally displaced permanent canine teeth in children
Fluorides for the prevention of white spots on teeth during fixed brace treatment
Initial arch wires for alignment of crooked teeth with fixed orthodontic braces (protocol stage)
Interspace/interdental brushes for oral hygiene in orthodontic patients with fixed appliances
Interventions for replacing missing teeth: denture chewing surface designs in edentulous people
Interventions for space closure in orthodontic treatment (protocol stage)
Occlusal adjustment for treating and preventing temporomandibular joint disorders
Occlusal splints for treating sleep bruxism (tooth grinding)
Optimum force for tooth movement in orthodontic treatment (protocol stage)
Oral appliances and functional orthopaedic appliances for obstructive sleep apnoea in children
Orthodontic and orthopaedic treatment for anterior open bite in children
Orthodontic treatment for crowded teeth in children (protocol stage)
Orthodontic treatment for deep bite and retroclined upper front teeth in children
Orthodontic treatment for posterior crossbites
Orthodontic treatment for prominent lower front teeth in children (protocol stage)
Orthodontic treatment for prominent upper front teeth in children
Orthodontics for treating temporomandibular joint (TMJ) disorders (protocol stage)
Reinforcement of anchorage during orthodontic brace treatment with implants or other surgical methods
Retention procedures for stabilising tooth position after treatment with orthodontic braces
Rigid versus wire fixation following jaw surgery for developmental dentofacial deformity (protocol stage)
Self-ligating orthodontic braces for straightening teeth (protocol stage)
Treatments for adults with prominent lower front teeth (protocol stage)
Cleft lip and palate (3)
Feeding interventions for growth and development in infants with cleft lip, cleft palate or cleft lip and palate
Interventions for the management of submucous cleft palate
Secondary bone grafting for alveolar cleft in children with cleft lip or cleft lip and palate (protocol stage)
Orthognathic surgery (1)
Orthognathic surgery for surgical correction of patients with mandibular deficiency (protocol stage)
Oral & Maxillofacial surgery (32)
Impacted teeth (1)
Open versus closed surgical exposure of canine teeth that are displaced in the roof of the mouth
Removal of third molars (2)
Interventions for treating asymptomatic impacted wisdom teeth in adolescents and adults
Surgical techniques for the removal of mandibular wisdom teeth (protocol stage)
Traumatic injury (7)
Domestic violence screening and intervention programmes for adults with dental or facial injury
Interventions for the management of external root resorption (protocol stage)
Interventions for treating traumatised ankylosed permanent front teeth (protocol stage)
Interventions for treating traumatised non-vital immature permanent front teeth: inducing a calcific barrier and root strengthening (protocol stage)
Interventions for treating traumatised permanent front teeth: avulsed (knocked out) and replanted (protocol stage)
Interventions for treating traumatised permanent front teeth: luxated (dislodged) teeth (protocol stage)
Interventions for treating traumatised permanent front teeth: root fracture (protocol stage)
Implants/prostheses (20)
Intervention for replacing missing teeth: Effect of type of implant-supported prostheses used to rehabilitate completely edentulous patients on treatment outcomes. (protocol stage)
Interventions for replacing missing teeth: 1- versus 2-stage implant placement
Interventions for replacing missing teeth: attachment systems for implant overdentures in edentulous jaws (protocol stage)
Interventions for replacing missing teeth: dental implants in fresh extraction sockets (immediate, immediate-delayed and delayed implants)
Interventions for replacing missing teeth: dental implants in zygomatic bone for the rehabilitation of the severely deficient edentulous maxilla
Interventions for replacing missing teeth: different times for loading dental implants
Interventions for replacing missing teeth: different types of dental implants
Interventions for replacing missing teeth: horizontal and vertical bone augmentation techniques for dental implant treatment
Interventions for replacing missing teeth: hyperbaric oxygen therapy for irradiated patients who require dental implants
Interventions for replacing missing teeth: maintaining and recovering soft tissue health around dental implants
Interventions for replacing missing teeth: management of soft tissues for dental implants
Interventions for replacing missing teeth: partially absent dentition (protocol stage)
Interventions for replacing missing teeth: preprosthetic surgery versus dental implants
Interventions for replacing missing teeth: resin-bonded bridges and other restorations for the replacement of adult teeth (protocol stage) (withdrawn)
Interventions for replacing missing teeth: surgical techniques for placing dental implants (withdrawn)
Interventions for replacing missing teeth: treatment of perimplantitis
Interventions for the treatment of fractures of the mandibular condyle (protocol stage)
Management of the fractured edentulous atrophic mandible
Resorbable versus titanium plates for facial fractures
Resorbable versus titanium plates for orthognathic surgery
Nerve injuries (2)
Interventions for iatrogenic inferior alveolar and lingual nerve injury (protocol stage)
Interventions for iatrogenic lingual nerve injury (protocol stage)
Oral cancer (12)
Ameloblastomas (1)
Interventions for treating ameloblastomas of the jaws (protocol stage)
Prevention (1)
Screening (1)
Screening programmes for the early detection and prevention of oral cancer
Treatment (5)
Interventions for the treatment of oral and oropharyngeal cancer: chemotherapy (protocol stage)
Interventions for the treatment of oral and oropharyngeal cancers: immunotherapy/biotherapy (protocol stage)
Interventions for the treatment of oral and oropharyngeal cancers: surgical treatment
Interventions for the treatment of oral cancer (protocol stage)
Interventions for the treatment of oral cancer: radiotherapy (protocol stage)
Oral care for cancer patients (5)
Interventions for preventing oral candidiasis for patients with cancer receiving treatment
Interventions for preventing oral mucositis for patients with cancer receiving treatment
Interventions for treating oral candidiasis for patients with cancer receiving treatment
Interventions for treating oral mucositis for patients with cancer receiving treatment
Pharmacological interventions for preventing salivary gland dysfunction following radiotherapy (protocol stage)
Oral mucositis (2)
Prevention (1)
Interventions for preventing oral mucositis for patients with cancer receiving treatment
Treatment (1)
Interventions for treating oral mucositis for patients with cancer receiving treatment
Prevention & Treatment (0)
Oral pain (15)
Endodontic pain (1)
Interventions for the management of post-endodontic pain (protocol stage)
Treatment (9)
Dentine hypersensitivity (1)
Potassium containing toothpastes for dentine hypersensitivity
Temporomandibular joint disorders (TMD) pain (8)
Arthroscopy (1)
Arthroscopy for temporomandibular disorders (protocol stage)
Cognitive-behavioural therapy (0)
Physical therapy (1)
Physical therapy for the management of patients with temporomandibular disorders and related pain. (protocol stage)
Splint therapy (2)
Anterior repositioning splint for temporomandibular joint disc displacement (protocol stage)
Stabilisation splint therapy for temporomandibular pain dysfunction syndrome
Intra-articular injections (1)
Hyaluronate for temporomandibular joint disorders
Pharmacological (1)
Pharmacological interventions for pain in patients with temporomandibular disorders (TMD) (protocol stage)
Arthrocentesis & lavage (1)
Arthrocentesis and lavage for treating temporomandibular joint disorders
Temporomandibular joint osteoarthritis (1)
Interventions for the management of temporomandibular joint osteoarthritis (protocol stage)
Post operative (4)
Amide local anaesthetics for post-operative pain relief following third molar surgery (protocol stage)
Ibuprofen for pain relief after surgical removal of lower wisdom teeth (protocol stage)
Ibuprofen versus paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth (protocol stage)
Paracetamol for pain relief after surgical removal of lower wisdom teeth
Chronic facial pain (0)
Orthodontic pain (1)
Drug interventions for pain relief during orthodontic treatment (protocol stage)
Oral medicine (11)
Prevention (0)
Infection control (0)
Treatment (11)
Oral lesions (10)
Acyclovir for treating primary herpetic gingivostomatitis
Interventions for recurrent aphthous stomatitis (mouth ulcers) (protocol stage)
Interventions for the management of oral submucous fibrosis
Interventions for the prevention and treatment of herpes simplex virus in patients being treated for cancer
Interventions for the restorative care of amelogenesis imperfecta in children and adolescents (protocol stage)
Interventions for treating denture stomatitis (protocol stage)
Interventions for treating oral haemangiomas in adults (protocol stage)
Interventions for treating oral leukoplakia
Interventions for treating oral lichen planus
The effectiveness of interventions for preventing and for treating dry socket. (protocol stage)
Burning mouth syndrome (1)
Interventions for the treatment of burning mouth syndrome
Antibiotic therapy (6)
Antibiotic use for irreversible pulpitis
Antibiotics for the prophylaxis of bacterial endocarditis in dentistry
Antibiotics to prevent complications following tooth extractions (protocol stage)
Interventions for replacing missing teeth: antibiotics at dental implant placement to prevent complications
Local delivery antimicrobials for chronic periodontitis (protocol stage)
Systemic antibiotics as adjunctive treatment for periodontitis (protocol stage)
Oral candidiasis (2)
Prevention (1)
Interventions for preventing oral candidiasis for patients with cancer receiving treatment
Treatment (1)
Interventions for treating oral candidiasis for patients with cancer receiving treatment
Dental anxiety (5)
Conscious sedation for dental anxiety (protocol stage)
Hypnosis for children undergoing dental treatment (protocol stage)
Psychological interventions for reducing dental anxiety in children (protocol stage)
Psychological interventions for reducing postoperative morbidity in dental surgery in adults (protocol stage)
Sedation of anxious children undergoing dental treatment
Maintenance (1)
Recall intervals for oral health in primary care patients
Cosmetic (2)
Home-based chemically-induced whitening of teeth in adults
Home-use whitening toothpastes for removal and prevention of stains in adults (protocol stage)