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Pain, Palliative and Supportive Care Group (183)
Supportive care (9)
Management (9)
Supporting patients and carers through the disease process (5)
Home-based palliative care for adults with cancer (protocol stage)
Homeopathy for adverse effects of cancer management (protocol stage)
Interventions for sexual dysfunction following treatments for cancer
Megestrol acetate for treatment of anorexia-cachexia syndrome
Supportive care for patients with gastrointestinal cancer
Supporting carers, dependants and others through bereavement (1)
Interventions to support children through bereavement (protocol stage)
Imparting bad news (0)
Information provision for patients and carers about the disease and treatment processes (0)
Nutritional support (3)
Nutrition support for bone marrow transplant patients
Nutritional screening for improving professional practice for patient outcomes in hospital and primary care settings (protocol stage)
Selenium for alleviating the side effects of chemotherapy, radiotherapy and surgery in cancer patients
Palliative care (47)
Management (19)
Lifestyle (2)
Exercise for the management of cancer-related fatigue in adults
Music therapy for end-of-life care (protocol stage)
Physical and pharmacological treatments (10)
Benzodiazepines and related drugs for insomnia in palliative care
Drug therapy for the management of cancer related fatigue
Drugs for the treatment of fatigue in palliative care (protocol stage)
Exercise for the management of cancer-related fatigue in adults
Interventions for the treatment of metastatic extradural spinal cord compression (protocol stage)
Neurokinin-1 receptor antagonists for prevention of chemotherapy-related nausea and vomiting (protocol stage)
Pleurodesis for malignant pleural effusions
Prevention and treatment interventions for nausea and vomiting during initiation of chronic opioid therapy (protocol stage)
Prevention and treatment of constipation in chronically ill children or children undergoing palliative care (protocol stage)
Whole brain radiotherapy for the treatment of multiple brain metastases
Complementary treatments (3)
Acupuncture-point stimulation for chemotherapy-induced nausea or vomiting
Aromatherapy and massage for symptom relief in patients with cancer (withdrawn)
Music therapy for end-of-life care (protocol stage)
Communication issues (0)
Organisation of support services (1)
Home-based palliative care for adults with cancer (protocol stage)
End of life issues (0)
Ethical issues (0)
Psychological issues (2)
Drug therapy for anxiety in palliative care
Psychotherapy for depression among incurable cancer patients
Service delivery (1)
Interventions for improving palliative care for older people living in nursing care homes (protocol stage)
Symptoms associated with palliative care (28)
Anorexia (1)
Megestrol acetate for treatment of anorexia-cachexia syndrome
Bowel obstruction (2)
Corticosteroids for the resolution of malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer
Surgery for the resolution of symptoms in malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer
Cachexia (2)
Eicosapentaenoic acid (EPA, an omega-3 fatty acid from fish oils) for the treatment of cancer cachexia
Megestrol acetate for treatment of anorexia-cachexia syndrome
Constipation (3)
Laxatives for the management of constipation in palliative care patients
Mu-opioid antagonists for opioid-induced bowel dysfunction
Prevention and treatment of constipation in chronically ill children or children undergoing palliative care (protocol stage)
Cough (0)
Delirium (1)
Drug therapy for delirium in terminally ill patients
Depression (1)
Psychotherapy for depression among incurable cancer patients
Dysphagia (0)
Ethical issues (0)
Fatigue (3)
Drug therapy for the management of cancer related fatigue
Exercise for the management of cancer-related fatigue in adults
Psychosocial interventions for reducing fatigue during cancer treatment in adults (protocol stage)
Hiccup (0)
Insomnia (1)
Benzodiazepines and related drugs for insomnia in palliative care
Itch (0)
Malignant acsites (0)
Mobility problems (0)
Nausea and vomiting (5)
Acupuncture-point stimulation for chemotherapy-induced nausea or vomiting
Droperidol for treatment of nausea and vomiting in palliative care patients (protocol stage)
Haloperidol for treatment of nausea and vomiting in palliative care patients (protocol stage)
Neurokinin-1 receptor antagonists for prevention of chemotherapy-related nausea and vomiting (protocol stage)
Prevention and treatment interventions for nausea and vomiting during initiation of chronic opioid therapy (protocol stage)
Oral health (1)
Parasympathomimetic drugs for the treatment of salivary gland dysfunction due to radiotherapy
Other symptoms (3)
Interventions for the treatment of metastatic extradural spinal cord compression (protocol stage)
Medically assisted hydration for palliative care patients
Medically assisted nutrition for palliative care patients (protocol stage)
Skin management (0)
Respiratory symptoms (4)
Dyspnoea (breathlessness) (3)
Non-pharmacological interventions for breathlessness in advanced stages of malignant and non-malignant diseases
Opioids for the palliation of breathlessness in terminal illness
Oxygen therapy for dyspnoea in adults
Death rattle (retained secretions) (1)
Interventions for noisy breathing in patients near to death
Drug-related symptoms (1)
Selenium for alleviating the side effects of chemotherapy, radiotherapy and surgery in cancer patients
Chronic cancer-related pain (23)
Management (23)
Psychological therapies (0)
Pharmacological therapies (17)
Anticonvulsant drugs for acute and chronic pain
Antipsychotics for acute and chronic pain (protocol stage)
Bisphosphonates for the relief of pain secondary to bone metastases
Buprenorphine for cancer pain (protocol stage)
Calcitonin for metastatic bone pain
Codeine, alone and with paracetamol (acetaminophen), for cancer pain (protocol stage)
Comparative efficacy of epidural, subarachnoid, and intracerebroventricular opioids in patients with pain due to cancer
Fentanyl for chronic pain (protocol stage)
Hydromorphone for acute and chronic pain
Ketamine as an adjuvant to opioids for cancer pain
Lamotrigine for acute and chronic pain
Methadone for cancer pain
NSAIDS or paracetamol, alone or combined with opioids, for cancer pain
Opioid switching to improve pain relief and drug tolerability
Opioids for the management of breakthrough (episodic) pain in cancer patients
Oral morphine for cancer pain
Oxycodone for cancer-related pain (protocol stage)
Invasive therapies (1)
Comparative efficacy of epidural, subarachnoid, and intracerebroventricular opioids in patients with pain due to cancer
Physical therapies (2)
Exercise for the management of cancer-related fatigue in adults
Transcutaneous electric nerve stimulation (TENS) for cancer pain in adults
Radiotherapy and radioisotopes (2)
Radioisotopes for metastatic bone pain
Radiotherapy for the palliation of painful bone metastases
Complementary therapies (1)
Music for pain relief
Management and prevention of cancer-related pain in children (0)
Chronic non-cancer pain (28)
Prevention (1)
Psychological therapies (0)
Pharmacological therapies (1)
Pharmacological management for prevention of phantom limb pain (protocol stage)
Complementary therapies (0)
Management (27)
Psychological therapies (1)
Psychological therapies for the management of chronic and recurrent pain in children and adolescents
Pharmacological therapies (19)
Anticonvulsant drugs for acute and chronic pain
Antidepressants for central pain (protocol stage)
Antidepressants for neuropathic pain
Antipsychotics for acute and chronic pain (protocol stage)
Carbamazepine for acute and chronic pain
Cyclobenzaprine for the treatment of myofascial pain in adults (protocol stage)
Fentanyl for chronic pain (protocol stage)
Gabapentin for acute and chronic pain
Hydromorphone for acute and chronic pain
Lamotrigine for acute and chronic pain
Local anesthetic sympathetic blockade for complex regional pain syndrome
Long-term opioid management for chronic noncancer pain (protocol stage)
Opioid switching to improve pain relief and drug tolerability
Opioids for neuropathic pain
Pain management for sickle cell disease
Pharmacotherapeutic interventions for treating phantom limb pain (protocol stage)
Pregabalin for acute and chronic pain (protocol stage)
Systemic administration of local anesthetic agents to relieve neuropathic pain
Topical lidocaine for the treatment of postherpetic neuralgia
Physical - invasive (2)
Spinal cord stimulation for chronic pain
Sympathectomy for neuropathic pain
Physical - non invasive (3)
Non-invasive physical treatments of myofascial pain (protocol stage)
Transcutaneous electrical nerve stimulation (TENS) for chronic pain
Transcutaneous electrical nerve stimulation (TENS) for persistent phantom and stump pain following amputation in adults (protocol stage)
Complementary therapies (2)
Music for pain relief
Touch therapies for pain relief in children and adults (protocol stage)
Management and prevention of chronic non-cancer pain in children (0)
Headache and migraine (25)
Prevention (12)
Psychological therapies (1)
Behavioral therapies for migraine (protocol stage)
Pharmacological therapies (8)
Anticonvulsant drugs for migraine prophylaxis
Drug therapy for preventing post-dural puncture headache (protocol stage)
Drugs for preventing migraine headaches in children
Flunarizine for the prevention of migraine (protocol stage)
Muscle relaxants versus placebo for tension-type headache prophylaxis (protocol stage)
Propranolol for migraine prophylaxis
Selective serotonin re-uptake inhibitors (SSRIs) for preventing migraine and tension-type headaches
Tricyclic antidepressants for the prevention of migraine and tension-type headache (protocol stage)
Other interventions (2)
Epidural blood patching for preventing and treating post-dural puncture headache
Posture and fluids for preventing post-dural puncture headache
Complementary therapies (1)
Feverfew for preventing migraine
Management (13)
Psychological therapies (1)
Behavioral therapies for migraine (protocol stage)
Pharmacological therapies (10)
Drugs by category/name (10)
Dipyrone for acute primary headaches
Drug therapy for preventing post-dural puncture headache (protocol stage)
Drugs for treating acute migraine headaches in children and adolescents (protocol stage)
Eletriptan for acute migraine (withdrawn)
Normobaric and hyperbaric oxygen therapy for migraine and cluster headache
Oral sumatriptan for acute migraine
Parenteral corticosteroids for acute migraine (protocol stage)
Parenteral dihydroergotamine (DHE) for acute migraine (protocol stage)
Parenteral metoclopramide for acute migraine (protocol stage)
Rizatriptan for acute migraine (withdrawn)
Drugs by different routes (0)
Other - eg timing, population differences, ethnicity (0)
Physical therapies (1)
Non-invasive physical treatments for chronic/recurrent headache
Complementary therapies (1)
Acupuncture for migraine prophylaxis
Acute pain (48)
Prevention (0)
Psychological therapies (0)
Pharmacological therapies (0)
Other interventions (0)
Management (43)
Psychological therapies (2)
Distraction (0)
Other psychological interventions (2)
Clinical hypnosis for acute pain in adults (protocol stage)
Psychological interventions for needle-related procedural pain and distress in children and adolescents
Pharmacological therapies (37)
Drugs by category/name (31)
Anticonvulsant drugs for acute and chronic pain
Antipsychotics for acute and chronic pain (protocol stage)
Carbamazepine for acute and chronic pain
Gabapentin for acute and chronic pain
Hydromorphone for acute and chronic pain
Intravenous or intramuscular parecoxib for acute postoperative pain in adults (protocol stage)
Lamotrigine for acute and chronic pain
Lidocaine for pain relief in burn injured patients
Pain management for sickle cell disease
Pain relief for femoral sheath removal in interventional cardiology patients (protocol stage)
Patient controlled opioid analgesia versus conventional opioid analgesia for postoperative pain
Perioperative ketamine for acute postoperative pain
Pregabalin for acute and chronic pain (protocol stage)
Single dose dipyrone for acute postoperative pain
Single dose dipyrone for acute renal colic pain
Single dose oral aspirin for acute pain
Single dose oral celecoxib for acute postoperative pain
Single dose oral dextropropoxyphene, alone and with paracetamol (acetaminophen), for postoperative pain
Single dose oral diclofenac for postoperative pain
Single dose oral dihydrocodeine for acute postoperative pain
Single dose oral etoricoxib for postoperative pain (protocol stage)
Single dose oral ibuprofen for postoperative pain
Single dose oral indometacin for the treatment of acute postoperative pain
Single dose oral lumiracoxib for postoperative pain
Single dose oral naproxen and naproxen sodium for acute postoperative pain in adults
Single dose oral oxycodone and oxycodone plus paracetamol (acetominophen) for acute postoperative pain
Single dose oral paracetamol (acetaminophen) for postoperative pain in adults
Single dose oral paracetamol (acetaminophen) with codeine for postoperative pain in adults
Single dose oral piroxicam for acute postoperative pain
Single dose oral rofecoxib for postoperative pain
Single dose propacetamol or IV paracetamol for postoperative pain (protocol stage)
Drugs by different routes (6)
EMLA and Amethocaine for reduction of children's pain associated with needle insertion
Epidural analgesia for pain relief following hip or knee replacement
Intravenous or intramuscular parecoxib for acute postoperative pain in adults (protocol stage)
Lidocaine for pain relief in burn injured patients
Patient controlled opioid analgesia versus conventional opioid analgesia for postoperative pain
Pre-incisional medication for postoperative pain (protocol stage)
Other - eg, timing, population differences, ethnicity (0)
Physical therapies (1)
Transcutaneous electrical nerve stimulation for acute pain (protocol stage)
Complementary therapies (3)
Acupuncture for the treatment of post-operative pain (protocol stage)
Music for pain relief
Touch therapies for pain relief in children and adults (protocol stage)
Management and prevention of acute pain in children (5)
Analgesics for postoperative pain after tonsillectomy and adenoidectomy in children (protocol stage)
Diclofenac for acute pain in children (protocol stage)
EMLA and Amethocaine for reduction of children's pain associated with needle insertion
Nonpharmacological interventions for needle-related procedural pain and post-operative pain in neonates and infants. (protocol stage)
Psychological interventions for needle-related procedural pain and distress in children and adolescents
Pain measurement tools (0)
Validation (0)
Type and application (0)
Symptoms associated with chemotherapy and radiotherapy (3)
Fatigue (2)
Drug therapy for the management of cancer related fatigue
Exercise for the management of cancer-related fatigue in adults
Nausea and vomiting (1)
Comparison of clinical efficacy of serotonin receptor antagonists in highly emetogenic chemotherapy (protocol stage)