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Infectious Diseases Group
(121)
Malaria
(48)
Diagnostics
(1)
Immunochromatography-based rapid diagnostic tests for diagnosing uncomplicated malaria in endemic countries
(protocol stage)
Prevention
(16)
Vaccines
(4)
Vaccines for preventing malaria
(withdrawn)
Vaccines for preventing malaria (SPf66)
Vaccines for preventing malaria (blood-stage)
Vaccines for preventing malaria (pre-erythrocytic)
Vector Control
(5)
Electronic mosquito repellents for preventing mosquito bites and malaria infection
Indoor residual spraying for preventing malaria
(protocol stage)
Insecticide-treated bed nets and curtains for preventing malaria
Insecticide-treated nets for preventing malaria in pregnancy
Larvivorous fish for malaria prevention
(protocol stage)
Drugs for prevention for people living in endemic areas
(5)
Chemoprophylaxis and intermittent treatment for preventing malaria in children
Drugs for preventing malaria in pregnant women
Intermittent preventive treatment regimens for malaria in HIV-positive pregnant women
(protocol stage)
Malaria chemoprophylaxis in sickle cell disease
Primaquine for reducing transmission of Plasmodium falciparum malaria
(protocol stage)
Drugs for prevention for travellers
(2)
Drugs for preventing malaria in travellers
Mefloquine for preventing malaria in non-immune adult travellers
(withdrawn)
Treatment
(30)
Treatment of uncomplicated falciparum malaria
(16)
Single agent
(4)
Amodiaquine for treating malaria
Azithromycin for treating uncomplicated malaria
(protocol stage)
Intrarectal quinine versus intravenous or intramuscular quinine for treating Plasmodium falciparum malaria
Pyronaridine for treating uncomplicated falciparum malaria
(protocol stage)
Combined treatment, non-artemisinin based
(3)
Atovaquone-proguanil for treating uncomplicated malaria
Chloroquine or amodiaquine combined with sulfadoxine-pyrimethamine for treating uncomplicated malaria
Chlorproguanil-dapsone for treating uncomplicated malaria
Combined treatment, artemisinin based
(8)
Artemether-lumefantrine (four-dose regimen) for treating uncomplicated falciparum malaria
Artemether-lumefantrine (six-dose regimen) for treating uncomplicated falciparum malaria
Artemether-lumefantrine for treating uncomplicated falciparum malaria
(withdrawn)
Artemisinin derivatives for treating severe malaria
Artemisinin derivatives for treating uncomplicated malaria
Artemisinin-based combination therapy for treating uncomplicated malaria
Artesunate plus mefloquine versus mefloquine for treating uncomplicated malaria
Sulfadoxine-pyrimethamine plus artesunate versus sulfadoxine-pyrimethamine plus amodiaquine for treating uncomplicated malaria
Drugs for treatment in special groups
(1)
Drugs for treating uncomplicated malaria in pregnant women
Treatment of vivax malaria
(1)
Primaquine for preventing relapses in people with Plasmodium vivax malaria
Treatment of severe malaria
(5)
Artemisinin derivatives for treating severe malaria
Artesunate versus quinine for treating severe malaria
High first dose quinine regimen for treating severe malaria
Intramuscular arteether for treating severe malaria
Intrarectal quinine versus intravenous or intramuscular quinine for treating Plasmodium falciparum malaria
Adjunctive treatment of severe malaria
(5)
Blood transfusion for treating malarial anaemia
Iron-chelating agents for treating malaria
Mannitol and other osmotic diuretics as adjuncts for treating cerebral malaria
Routine anticonvulsants for treating cerebral malaria
Steroids for treating cerebral malaria
Symptomatic treatment
(3)
Antipyretic measures for treating fever in malaria
Oral iron supplementation for preventing or treating anaemia among children in malaria-endemic areas
Zinc supplementation for preventing and treating malaria in children living in malaria-endemic areas
(protocol stage)
Delivery strategies
(1)
Unit-dose packaged drugs for treating malaria
Tuberculosis
(21)
Diagnostics (0)
Prevention
(3)
Isoniazid for preventing tuberculosis in non-HIV infected persons
Isoniazid monotherapy versus other monotherapies or combination chemotherapy for preventing active tuberculosis in HIV-negative persons
(protocol stage)
Mycobacterium vaccae immunotherapy for treating tuberculosis
Treatment
(13)
Drugs
(10)
Adjunctive steroid therapy for managing tuberculosis
(protocol stage)
Corticosteroids for managing tuberculous meningitis
Corticosteroids for tuberculous pleurisy
Drugs for preventing tuberculosis in people at risk of multiple-drug-resistant pulmonary tuberculosis
Fluoroquinolones for treating tuberculosis
Fully intermittent dosing with drugs for treating tuberculosis in adults
Intermittent versus daily therapy for treating tuberculosis in children
(protocol stage)
Interventions for treating tuberculous pericarditis
Regimens of less than six months for treating tuberculosis
Rifabutin for treating pulmonary tuberculosis
Other
(3)
Low level laser therapy for treating tuberculosis
Nutritional supplements for people being treated for active tuberculosis
Routine surgery in addition to chemotherapy for treating spinal tuberculosis
Delivery strategies
(5)
Directly observed therapy for treating tuberculosis
Education and counselling for promoting adherence to the treatment of active tuberculosis
(protocol stage)
Incentives for improving patient adherence to anti-tuberculosis treatment
(protocol stage)
Interventions for promoting adherence to tuberculosis management
(withdrawn)
Reminder systems and late patient tracers in the diagnosis and management of tuberculosis
Diarrhoeal infections
(21)
Principles of prevention and management
(14)
Prevention
(3)
Hand washing for preventing diarrhoea
Interventions to improve excreta disposal for preventing diarrhoea
(protocol stage)
Interventions to improve water quality for preventing diarrhoea
Rehydration
(4)
Glucose-based rehydration solution (ORS) for treating dehydration caused by acute diarrhoea in children
Oral versus intravenous rehydration for treating dehydration due to gastroenteritis in children
Polymer-based oral rehydration solution for treating acute watery diarrhoea
Rice-based oral rehydration solution for treating diarrhoea
(withdrawn)
Anti-infective treatment
(4)
Antiamoebic drugs for treating amoebic colitis
Antibiotic treatment for travellers' diarrhoea
Probiotics for treating infectious diarrhoea
Probiotics for treating persistent diarrhoea in children
(protocol stage)
Management
(3)
Early versus delayed refeeding for children with acute diarrhoea
(protocol stage)
Lactose avoidance for acute diarrhoea in children less than five years
(protocol stage)
Oral zinc for treating diarrhoea in children
Prevention and management of specific infections
(7)
Cholera
(2)
Reduced osmolarity oral rehydration solution for treating cholera
Vaccines for preventing cholera: killed whole cell or other subunit vaccines (injected)
Giardiasis
(2)
Drugs for treating giardiasis
(withdrawn)
Drugs for treating giardiasis
(protocol stage)
Rotavirus
(1)
Rotavirus vaccine for preventing diarrhoea
Salmonellosis
(1)
Antibiotics for treating salmonella gut infections
Shigellosis
(1)
Antibiotic therapy for Shigella dysentery
Neglected tropical diseases
(5)
Human African Trypanosomiasis
(1)
Chemotherapy of second-stage Human African trypanosomiasis
(protocol stage)
Lymphatic filariasis
(2)
Albendazole for lymphatic filariasis
Diethylcarbamazine (DEC)-medicated salt for community-based control of lymphatic filariasis
Schistosomiasis
(2)
Drugs for treating urinary schistosomiasis
Interventions for treating schistosomiasis mansoni
Visceral leishmaniasis (0)
Other
(26)
Anthrax
(2)
Vaccines for preventing anthrax
(withdrawn)
Vaccines for preventing anthrax
Brucellosis
(1)
Antibiotics for treating human brucellosis
(protocol stage)
Cysticercosis
(2)
Anthelmintics for people with neurocysticercosis
(protocol stage)
Drugs for treating neurocysticercosis (tapeworm infection of the brain)
(withdrawn)
Dengue
(2)
Prevention
(1)
Vaccines for preventing dengue infection
(protocol stage)
Treatment
(1)
Corticosteroids for treating dengue shock syndrome
Epidemic typhus (0)
Fever management
(2)
Paracetamol versus placebo or physical methods for treating fever in children
Physical methods versus drug placebo or no treatment for managing fever in children
Headlice
(1)
Interventions for treating headlice
(withdrawn)
Helminths, soil transmitted
(1)
Deworming drugs for treating soil-transmitted intestinal worms in children: effects on growth and school performance
Japanese encephalitis
(1)
Vaccines for preventing Japanese encephalitis
Melioidosis
(1)
Interventions for treating melioidosis
Paracoccidioidomycosis
(1)
Drugs for treating paracoccidioidomycosis
Paraveterinary services impact on human health
(1)
Community animal health services for improving household wealth and health status of low income farmers
Plague
(1)
Vaccines for preventing plague
Scabies
(1)
Interventions for treating scabies
Scrub typhus
(1)
Antibiotics for treating scrub typhus
Smallpox
(1)
Vaccines for preventing smallpox
Snake bites
(1)
Interventions for preventing reactions to snake antivenom
Strongyloidiasis
(1)
Azoles and ivermectin for treating strongyloides infection
(protocol stage)
Tick-borne encephalitis
(1)
Vaccines for preventing tick-borne encephalitis
Trichomoniasis
(1)
Interventions for treating trichomoniasis in women
Typhoid and paratyphoid fever (enteric fever)
(3)
Azithromycin for treating uncomplicated typhoid and paratyphoid fever (enteric fever)
Fluoroquinolones for treating typhoid and paratyphoid fever (enteric fever)
Vaccines for preventing typhoid fever
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