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Heart Group
(140)
Cardiovascular diseases
(18)
Prevention
(18)
Drugs
(5)
Antiplatelets
(1)
Aspirin for primary prevention of coronary heart disease
(protocol stage)
Lipid Lowering
(2)
Interventions to improve adherence to lipid lowering medication
Statins for the primary prevention of cardiovascular disease
(protocol stage)
Other
(2)
Homocysteine lowering interventions for preventing cardiovascular events
Hormone replacement therapy for preventing cardiovascular disease in post-menopausal women
Lifestyle
(8)
Dietary
(4)
Dietary or food supplements
(4)
Dietary advice for reducing cardiovascular risk
Omega 3 fatty acids for prevention and treatment of cardiovascular disease
Reduced or modified dietary fat for preventing cardiovascular disease
Supplemental plant sterols and stanols for serum cholesterol and cardiovascular disease
(protocol stage)
Exercise
(1)
Interventions for promoting physical activity
Other lifestyle interventions
(3)
Interventions for preventing obesity in children
Interventions for treating obesity in children
Multiple risk factor interventions for primary prevention of coronary heart disease_KJW
Psychological
(0)
Education or counselling (0)
Complementary treatments
(2)
Artichoke leaf extract for treating hypercholesterolaemia
Chuanxiong preparations for preventing stroke
(protocol stage)
Policy Related
(0)
Food policy initiatives (0)
Health promotion campaigns (0)
Social & economic developments (0)
Other interventions
(3)
Continuous positive airway pressure for cardiovascular disease associated with sleep apneoa
(protocol stage)
Influenza vaccines for preventing coronary heart disease
Risk scoring for the primary prevention of cardiovascular disease
(protocol stage)
Myocardial ischemia/ Coronary disease
(57)
Drugs
(6)
ACE inhibitors (0)
Adrenergic agents
(0)
Betablockers (0)
Antibiotics
(1)
Antibiotics for secondary prevention of coronary heart disease
(protocol stage)
Thrombolytics / Fibrinolytics
(4)
Antiplatelets [Aspirin; clopidogrel; glycoprotein IIb/IIIa inhibitors; ticlopidine]
(2)
Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular disease
Ticlopidine versus oral anticoagulation for coronary stenting
Anticoagulants
(2)
Oral anticoagulants for the secondary prevention of coronary heart disease
(protocol stage)
Xa inhibitors for acute coronary syndromes
(protocol stage)
Lipid lowering drugs (0)
Other
(1)
Psychological and pharmacological interventions for depression in patients with coronary artery disease
(protocol stage)
Lifestyle
(6)
Diet
(2)
Low glycaemic index diets for coronary heart disease
Wholegrain cereals for coronary heart disease
Exercise (0)
Rehabilitation
(3)
Exercise-based rehabilitation for coronary heart disease
Home-based versus centre-based cardiac rehabilitation
(protocol stage)
Promoting patient uptake and adherence in cardiac rehabilitation
(protocol stage)
Smoking cessation
(1)
Smoking cessation for the secondary prevention of coronary heart disease
Psychological
(2)
Counseling / Education (0)
Other
(2)
Psychological and pharmacological interventions for depression in patients with coronary artery disease
(protocol stage)
Psychological interventions for coronary heart disease
Percutaneous coronary interventions
(2)
Drug-eluting stents versus bare metal stents for angina or acute coronary syndromes: a systematic review
(protocol stage)
Percutaneous transluminal coronary angioplasty with stents versus coronary artery bypass grafting for people with stable angina or acute coronary syndromes
Surgery
(8)
Coronary Artery Bypass Grafting [CABG]
(8)
Bilateral versus single internal mammary artery bypass grafts for coronary arterial atherosclerosis
(protocol stage)
Hypothermia to reduce neurological damage following coronary artery bypass surgery
Incentive spirometry for preventing pulmonary complications after coronary artery bypass graft
Off-pump versus on-pump coronary artery bypass grafting for ischaemic heart disease
(protocol stage)
Percutaneous transluminal coronary angioplasty with stents versus coronary artery bypass grafting for people with stable angina or acute coronary syndromes
Perioperative intravenous magnesium for preventing atrial fibrillation following coronary artery bypass
(protocol stage)
Preoperative intra aortic balloon pumps in patients undergoing coronary artery bypass grafting
Prophylactic corticosteroids for cardiopulmonary bypass in adults
(protocol stage)
Complementary treatments
(1)
Music for stress and anxiety reduction in coronary heart disease patients
Other (including organisational)
(2)
Service organisation for the secondary prevention of ischaemic heart disease
(protocol stage)
Stem cell therapy for ischaemic heart disease and congestive heart failure
(protocol stage)
Angina
(7)
Drugs
(3)
Beta blockers
(1)
Beta blockers for stable angina
(protocol stage)
Calcium channel blockers (0)
Lipid lowering agents
(0)
Statins (0)
Nitrates
(1)
Nitrates for stable angina
(protocol stage)
Thrombolytics / Fibrinolytics
(0)
Antiplatelets [Aspirin / Glycoprotein IIb / IIIa inhibitors] (0)
Anticoagulants [Heparin / Warfarin] (0)
Clopidigrel (0)
Ticlopidine (0)
Vasodilators
(1)
Trimetazidine for stable angina
Percutaneous coronary interventions
(1)
Transmyocardial laser revascularization versus medical therapy for refractory angina
Surgery (0)
Complementary treatments
(2)
Chinese herbal medicine suxiao jiuxin wan for angina pectoris
Traditional Chinese patent medicine for Stable Angina
(protocol stage)
Other
(1)
Enhanced external counterpulsation for chronic angina pectoris
(protocol stage)
Acute coronary syndrome [Myocardial Infarction; Unstable angina]
(23)
Drugs
(9)
Adrenergic agents
(2)
Beta blockers
(2)
Beta-blockers for myocardial infarction
(protocol stage)
Beta-blockers for unstable angina
(protocol stage)
Antiarrhythmics (0)
Calcium channel blockers
(1)
Calcium antagonists for unstable angina
(protocol stage)
Lipid lowering agents
(1)
Statins for acute coronary syndrome
(protocol stage)
Nitrates (0)
Thrombolytics / Fibrinolytics
(4)
Thrombolysis (0)
Antiplatelets [aspirin; clopidogrel; glycoprotein IIb / IIIa inhibitors; ticlopidine]
(1)
Platelet glycoprotein IIb/IIIa blockers for percutaneous coronary intervention and the initial treatment of non-ST segment elevation acute coronary syndromes
Anticoagulants [Heparin / Warfarin]
(3)
Heparin for ST-segment elevation myocardial infarction
(protocol stage)
Heparin versus placebo for acute coronary syndromes
Low molecular weight heparins versus unfractionated heparin for acute coronary syndromes
Vasodilators (0)
Other
(1)
Intravenous magnesium for acute myocardial infarction
Percutaneous coronary interventions
(3)
Percutaneous transluminal rotational atherectomy for coronary artery disease
Primary angioplasty versus intravenous thrombolysis for acute myocardial infarction
(withdrawn)
Primary stenting versus primary balloon angioplasty for treating acute myocardial infarction
Surgery (0)
Invasive versus conservative management
(1)
Early invasive versus conservative strategies for unstable angina & non-ST-elevation myocardial infarction in the stent era
Complementary treatments
(4)
Danshen (Chinese medicinal herb) preparations for acute myocardial infarction
Huangqi preparation for unstable angina
(protocol stage)
Puerarin injection for unstable angina pectoris
Tongxinluo (Tong xin luo or Tong-xin-luo) capsule for unstable angina pectoris
Other treatments
(6)
Bed rest for acute uncomplicated myocardial infarction
Chest pain observation units for patients with symptoms suggestive of acute cardiac ischaemia
(protocol stage)
Hyperbaric oxygen therapy for acute coronary syndrome
Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock
(protocol stage)
Oxygen therapy for acute myocardial infarction
(protocol stage)
Stem cell treatment for acute myocardial infarction
Heart Arrest
(5)
Drugs
(2)
Adrenaline and vasopressin for cardiac arrest
(protocol stage)
Aminophylline for bradyasystolic cardiac arrest in adults
(protocol stage)
Non drugs
(3)
Active chest compression-decompression for cardiopulmonary resuscitation
Biphasic versus monophasic waveforms for transthoracic defibrillation in out-of-hospital cardiac arrest
(protocol stage)
Mechanical chest compressions versus manual chest compressions for cardiac arrest
(protocol stage)
Organisational
(0)
Pre-hospital interventions; coronary ambulances (0)
General public cardiopulmonary resuscitation training (0)
Abnormal Heart Rhythms [Arrhythmias]
(14)
Atrial fibrillation
(9)
Drugs
(5)
All drugs
(2)
Pharmacological cardioversion for atrial fibrillation and flutter
Rhythm control versus rate control for atrial fibrillation/flutter
(protocol stage)
ACE inhibitors (0)
Adrenergic agents
(0)
Beta blockers (0)
Antiarrhythmics
(1)
Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation
Calcium channel blockers (0)
Cardiac glycosides (0)
Diuretics (0)
Lipid lowering agents
(0)
Statins (0)
Nitrates (0)
Phosphodiesterase inhibitors (0)
Potassium channel blockers (0)
Thrombolytics / Fibrinolytics
(2)
Antiplatelets [Aspirin / Glycoprotein IIb / IIIa inhibitors]
(1)
Anticoagulants or antiplatelet therapy for non-rheumatic atrial fibrillation and flutter
(withdrawn)
Anticoagulants [Heparin / Warfarin]
(1)
Self-monitoring and self-management of oral anticoagulation
(protocol stage)
Clopidigrel (0)
Ticlopidine (0)
Vasodilators (0)
Electrical / Pacing
(2)
Electrical cardioversion for atrial fibrillation and flutter
Rhythm control versus rate control for atrial fibrillation/flutter
(protocol stage)
Other
(2)
Catheter ablation for paroxysmal and persistent atrial fibrillation
(protocol stage)
Surgical ablation for atrial fibrillation
(protocol stage)
Paroxysmal tachycardia
(0)
Drugs (0)
Electrical / Pacing (0)
Supraventricular tachycardia
(1)
Drugs
(1)
Adenosine versus intravenous calcium channel antagonists for the treatment of supraventricular tachycardia in adults
Electrical / Pacing (0)
Ventricular tachycardia
(2)
Drugs
(1)
Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death
(protocol stage)
Electrical / Pacing
(1)
Cognitive behavourial therapy for patients with implantable cardioverter-defibrillators
(protocol stage)
Sick Sinus Syndrome
(1)
Drugs (0)
Electrical / Pacing
(1)
Dual chamber versus single chamber ventricular pacemakers for sick sinus syndrome and atrioventricular block
Heart Block
(1)
Electrical / Pacing
(1)
Implantable defibrillator versus pharmacotherapy for Brugada syndrome
(protocol stage)
Heart Failure and Left Ventricular Dysfunction
(27)
Drugs
(16)
Adrenergic agents
(2)
Beta blockers
(2)
Beta-blockers for congestive heart failure in children
Beta-blockers for heart failure
(protocol stage)
Angiotensin converting enzyme [ACE] inhibitors
(1)
Angiotensin converting enzyme inhibitors for heart failure
(protocol stage)
Angiotensin II antagonists
(1)
Angiotensin receptor blockers for heart failure
(protocol stage)
Antiarrhythmics
(0)
Amiodarone (0)
Lignocaine (0)
Antibiotics (0)
Anti-inflammatory agents (0)
Calcium channel blockers
(1)
Second generation dihydropyridine calcium channel blockers for heart failure
(protocol stage)
Cardiac glycosides
(1)
Digitalis for treatment of congestive heart failure in patients in sinus rhythm
Diuretics
(2)
Continuous infusion versus bolus injection of loop diuretics in congestive heart failure
Diuretics for heart failure
Natriuretic peptides
(1)
Natriuretic peptides for acute heart failure syndromes
(protocol stage)
Nitrates
(2)
Nitrates for acute heart failure
(protocol stage)
Nitrates for chronic heart failure
(protocol stage)
Phosphodiesterase inhibitors
(1)
Phosphodiesterase III inhibitors for heart failure
Potassium channel blockers (0)
Thrombolytics / Fibrinolytics
(2)
Antiplatelets [Aspirin and Glycoprotein IIb / IIIa inhibitors]
(1)
Antiplatelet agents versus control or anticoagulation for heart failure in sinus rhythm
Anticoagulation [Heparin and Warfarin]
(1)
Anticoagulation for heart failure in sinus rhythm
Clopidigrel (0)
Ticlopidine (0)
Vasodilators (0)
Management of Medication
(1)
Interventions to improve evidence-based prescribing for heart failure
(protocol stage)
Other
(1)
Erythropoiesis-stimulating agents for anaemia in chronic heart failure patients
(protocol stage)
Surgery
(1)
Heart Transplantation
(1)
Primary immunosuppression following heart transplantation
(protocol stage)
Myomectomy (0)
Ventricular assist devices (0)
Electrical / Pacing (0)
Lifestyle
(3)
Diet (0)
Rehabilitation
(3)
Exercise based rehabilitation for heart failure
Home-based versus centre-based cardiac rehabilitation
(protocol stage)
Promoting patient uptake and adherence in cardiac rehabilitation
(protocol stage)
Psychological
(1)
Psychological interventions for depression in heart failure
Complementary treatments
(2)
Hawthorn extract for treating chronic heart failure
Shengmai (a traditional Chinese herbal medicine) for heart failure
Organisational
(2)
Clinical service organisation for heart failure
Structured telephone support or telemonitoring programs for patients with chronic heart failure
(protocol stage)
Other
(1)
Stem cell therapy for ischaemic heart disease and congestive heart failure
(protocol stage)
Acute heart failure
(1)
Non-invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary edema
Myocardial Disease
(5)
Chagas Cardiomyopathy
(2)
Drugs
(2)
Trypanocidal drugs for chronic asymptomatic Trypanosoma cruzi infection
Trypanocidal drugs for late stage, symptomatic Chagas disease (Trypanosoma cruzi infection)
Surgery (0)
Other (0)
Dilated cardiomyopathy
(0)
Drugs
(0)
ACE inhibitors (0)
Adrenergic agents
(0)
Betablockers (0)
Calcium channel blockers (0)
Nitrates (0)
Surgery (0)
Electrical / Pacing (0)
Other (0)
Hypertrophic cardiomyopathy
(0)
Drugs
(0)
Antiarrhythmics (0)
Adrenergic agents
(0)
Betablockers (0)
Calcium channel blockers (0)
Surgery
(0)
Myomectomy (0)
Electrical / Pacing (0)
Psychological
(0)
Counselling / education (0)
Complementary treatments (0)
Other (0)
Myocarditis
(3)
Drugs
(2)
Corticosteroids for viral myocarditis
Intravenous immunoglobulin for presumed viral myocarditis in children and adults
Complementary treatments
(1)
Herbal medicines for viral myocarditis
Other (0)
Endocarditis
(0)
Drugs (0)
Complementary Treatments (0)
Other (0)
Rheumatic Heart Disease
(2)
Drugs
(2)
Anti-inflammatory treatment for carditis in acute rheumatic fever
Penicillin for secondary prevention of rheumatic fever
Heart Valve Disease
(2)
Drugs
(2)
Antibiotic prophylaxis (0)
Adrenergic agents
(1)
Betablockers
(1)
Beta-blockers for mitral stenosis
(protocol stage)
Cardiac glycosides (0)
Thrombolytics / Fibrinolytics
(1)
Antiplatelet and anticoagulation for patients with prosthetic heart valves
Surgery
(0)
Balloon valvuloplasty (0)
Valve repair (0)
Valve replacement (0)
Other (0)
Congenital Heart Abnormalities
(4)
Drugs
(2)
Antibiotics for brain abscesses in people with cyanotic congenital heart disease
Beta-blockers for congestive heart failure in children
Surgery
(1)
Prophylactic steroids for pediatric open heart surgery
Psychological
(1)
Psychological interventions for depression in adolescent and adult congenital heart disease
Complementary Treatments (0)
Heart Surgery [Not specific to disease areas above]
(3)
Fresh frozen plasma for cardiovascular surgery
(protocol stage)
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery
Mediastinal chest drain clearance for cardiac surgery
Other
(3)
Cognitive behavourial therapy for patients with implantable cardioverter-defibrillators
(protocol stage)
Drugs and pacemakers for neurally mediated reflex syncope
(protocol stage)
Psychological interventions for symptomatic management of non-specific chest pain in patients with normal coronary anatomy
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