Cochrane Reviews - by sub-topics 'Dementia and Cognitive Improvement'

Thiamine for Alzheimer's disease

Pyritinol (0)

Pyroglutamic acid (0)

Rifampin (1)

Antibiotics and antivirals for dementia and mild cognitive impairment (protocol stage)

Rofecoxib (0)

SGS-742 (0)

Statins (Atorvastatin) (1)

Statins for the treatment of Alzheimer's disease and dementia (protocol stage)

Tarenflurbil (0)

Thiamine (2)

Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse

Vaccines (AN-1792) (0)

Vitamin B supplements (0)

Vitamin B3 (Niacin) (0)

Vitamin B6 (Pyroxidine) (1)

Vitamin B6 for cognition

Vitamin B12 (1)

Vitamin B12 for cognition

Vitamin D derivative (0)

Vitamin E (1)

Vitamin E for Alzheimer's disease and mild cognitive impairment

Wine (red) (0)

Xanomeline (0)

Xianlong (0)

Yi Zhi (1)

Yizhi capsule for vascular dementia

Zhiling (1)

Zhiling decoction for vascular dementia

Interventions aimed at interrupting disease processes (52)

ABT-418 (0)

Acetyl-l-carnitine (1)

Acetyl-l-carnitine for dementia

AF 102B (0)

Almitrine-Raubasine (1)

Almitrine-Raubasine combination for dementia (protocol stage)

Alpha-lipoic acid (1)

Alpha lipoic acid for dementia

Alzhemed (1)

Tramiprosate (Alzhemed) for Alzheimer's disease (protocol stage)

Ampalex (CX 516) (0)

AIP 001 (0)

Anapsos (0)

Aniracetam (0)

Arecholine (0)

Bacopa monniera (0)

Besipirdine (HP 749) (0)

Beta & Gamma-Secretase Inhibitors (0)

Cannabis (0)

CDP-choline (1)

Cytidinediphosphocholine (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly

Cerebrolysin (1)

Cerebrolysin for Alzheimer's disease (protocol stage)

Cerestat (Aptigane) (0)

Chlorpromazine (0)

Clioquinol (1)

Metal protein attenuating compounds for the treatment of Alzheimer's disease

Colostrinin (0)

Cyclandelate (0)

Dapsone (0)

D-cycloserine (1)

D-cycloserine for Alzheimer's disease

Desferrioxamine mesylate (0)

Denbufylline (0)

Donepezil (5)

Cholinesterase inhibitors for Alzheimer's disease

Cholinesterase inhibitors for Parkinson's disease dementia

Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease (protocol stage)

Donepezil for dementia due to Alzheimer's disease

Donepezil for vascular dementia

Ebselen (DR-3305) (0)

Eptastigmine (0)

Fluphenazine (Modecate) (0)

Galantamine (5)

Cholinesterase inhibitors for Alzheimer's disease

Cholinesterase inhibitors for Parkinson's disease dementia

Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease (protocol stage)

Galantamine for Alzheimer's disease and mild cognitive impairment

Galantamine for vascular cognitive impairment

Gastrodine (0)

Ginkgo biloba (1)

Ginkgo biloba for cognitive impairment and dementia

Ginseng (1)

Ginseng for cognition (protocol stage)

GSK-3 (0)

Homoeopathy (1)

Homeopathy for dementia

Huperzine (2)

Huperzine A for Alzheimer's disease

Huperzine A for vascular dementia

Hydergine (1)

Hydergine for dementia

Idebenone (0)

Indomethacin (1)

Indomethacin for Alzheimer's disease

Lazabemide (0)

Lecithin (1)

Lecithin for dementia and cognitive impairment

Leuprolide (0)

Linopirdine (DUP996) (0)

Lithium (0)

LU25-109 (0)

MKC-231 (0)

Memantine (1)

Memantine for dementia

Memric (SB 202026) (0)

Melatonin (1)

Melatonin for the treatment of dementia

Metrifonate (1)

Metrifonate for Alzheimer's disease

Milacemide (0)

Milameline (0)

Moclobemide (0)

Montirelin (NS-3) (0)

Naftidrofuryl (1)

Naftidrofuryl for dementia (protocol stage)

Naproxen (0)

Nebracetam (0)

Nefiracetam (0)

Neotrofin (AIT 082) (0)

Neromexine (0)

Nicaraven (AVS) (0)

Nicergoline (1)

Nicergoline for dementia and other age associated forms of cognitive impairment

Nicotine (1)

Nicotine for Alzheimer's disease

Nimodipine (1)

Nimodipine for primary degenerative, mixed and vascular dementia

NS2330 (0)

Oxiracetam (0)

Ondansetron (0)

Oxygen therapy (0)

Pentoxifylline (0)

Phenserine (0)

Physostigmine (0)

Picamilone (0)

Piracetam (1)

Piracetam for dementia or cognitive impairment

Posatirelin (1)

Posatirelin (l-pyro-2-aminoadipyl-l-leucyl-l-prolinamide) treatment for persons with dementia (protocol stage)

Propentofylline (1)

Propentofylline for dementia

Quilostigmine (S-12024) (0)

Quinacrine (0)

Rivastigmine (5)

Cholinesterase inhibitors for Alzheimer's disease

Cholinesterase inhibitors for Parkinson's disease dementia

Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease (protocol stage)

Rivastigmine for Alzheimer's disease

Rivastigmine for vascular cognitive impairment

Rofecoxib (0)

Sabeluzole (0)

SB 202026 (0)

Selegiline (1)

Selegiline for Alzheimer's disease

Senilex (0)

Shunts (1)

Shunting for normal pressure hydrocephalus (NPH)

SR 57746A (0)

Statins (1)

Statins for the prevention of dementia

Sunonacrine (0)

Tacrine (4)

Cholinesterase inhibitors for Parkinson's disease dementia

Cholinesterase inhibitors for dementia with Lewy bodies

Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease (protocol stage)

Tacrine for Alzheimer's disease (withdrawn)

Taltirelin (TA-0910) (0)

Thiazolidinediones (0)

Velnacrine (1)

Velnacrine for Alzheimer's disease

Vinpocetine (1)

Vinpocetine for cognitive impairment and dementia

WAL-2014 (0)

Xanomeline (0)

Yi-Zhi-Jian-Shen-Jing (0)

Yi Zhi (1)

Yizhi capsule for vascular dementia

Xianlong (0)

Zhiling (1)

Zhiling decoction for vascular dementia

Management of manifestations of the disease (64)

Aggression (5)

Anti-psychotic withdrawal (1)

Withdrawal versus continuation of chronic antipsychotic drugs for behavioural and neuropsychiatric symptoms in elderly patients with dementia (protocol stage)

Carbamazepine (1)

Carbamazepine and oxcarbazepine for the treatment of behavioural and psychological symptoms of dementia (BPSD) (protocol stage)

Chlorpromazine (Largactil) (0)

Clopenthixol (Clopixol) (0)

Fluphenazine (Modecate) (0)

Lorazepam (0)

Melperone (0)

Oxazepam (0)

Promazine (0)

Sodium valproate (1)

Tiapride (0)

Thioridazine (1)

Valproic acid (1)

Atypical antipsychotics for aggression and psychosis associated with dementia

Agitation (17)

Anti-psychotic withdrawal (1)

Withdrawal versus continuation of chronic antipsychotic drugs for behavioural and neuropsychiatric symptoms in elderly patients with dementia (protocol stage)

Aripiprazole (1)

Benzodiazepines (0)

Cannabis derivatives (1)

Cannabinoids for the treatment of dementia

Carbamazepine (1)

Carbamazepine and oxcarbazepine for the treatment of behavioural and psychological symptoms of dementia (BPSD) (protocol stage)

Chlorpromazine (Largactil) (0)

Clopenthixol (Clopixol) (0)

Clozapine (1)

Atypical antipsychotics for aggression and psychosis associated with dementia

Diazepam (0)

Divalproex sodium (1)

Haloperidol for agitation in dementia

Gabapentin (0)

Haloperidol (1)

Lorazepam (0)

Melperone (0)

Music therapy (1)

Atypical antipsychotics for aggression and psychosis associated with dementia

Olanzapine (1)

Oxazepam (0)

Promazine (0)

Psychosocial interventions (0)

Quetiapine (1)

Atypical antipsychotics for aggression and psychosis associated with dementia

Reality orientation (1)

Reality orientation for dementia (withdrawn)

Reminiscence therapy (1)

Reminiscence therapy for dementia

Risperidone (1)

Atypical antipsychotics for aggression and psychosis associated with dementia

Thioridazine (1)

Trazodone for agitation in dementia

Tiapride (0)

Trazodone (1)

Validation therapy (1)

Validation therapy for dementia

Valproic acid (1)

Anxiety (5)

Anti-psychotic withdrawal (1)

Withdrawal versus continuation of chronic antipsychotic drugs for behavioural and neuropsychiatric symptoms in elderly patients with dementia (protocol stage)

Cannabis derivatives (0)

Flurazepam (Dalmane) (0)

Gabapentin (0)

Music therapy (1)

Reminiscence therapy for dementia

Psychosocial (0)

Reality orientation (1)

Reality orientation for dementia (withdrawn)

Reminiscence therapy (1)

Benzodiazepines (0)

Validation Therapy (1)

Validation therapy for dementia

Apathy (0)

Carer burden (3)

Cognitive and behavioural interventions (1)

Cognitive reframing for carers of people with dementia (protocol stage)

Support (2)

Information and support interventions for informal caregivers of people with dementia (protocol stage)

Respite care for people with dementia and their carers

Psycho-educational interventions (0)

Delusions (1)

Anti-psychotic withdrawal (1)

Withdrawal versus continuation of chronic antipsychotic drugs for behavioural and neuropsychiatric symptoms in elderly patients with dementia (protocol stage)

Depression (15)

Amitriptyline (Lentizol) (1)

Antidepressants for treating depression in dementia

Amoxapine (1)

Antidepressants for treating depression in dementia

Citalopram (1)

Antidepressants for treating depression in dementia

Dothiepin (Prothiaden) (1)

Antidepressants for treating depression in dementia

Doxepin (Sinequan) (1)

Antidepressants for treating depression in dementia

Fluoxetine (Prozac) (1)

Antidepressants for treating depression in dementia

Imipramine (1)

Antidepressants for treating depression in dementia

Lofepramine (Gamanil) (1)

Antidepressants for treating depression in dementia

Mirtazipine (1)

Antidepressants for treating depression in dementia

Nefazodone (1)

Antidepressants for treating depression in dementia

Nortiptyline (Allegron) (1)

Antidepressants for treating depression in dementia

Paroxetine (Seroxat) (1)

Antidepressants for treating depression in dementia

Psychosocial (0)

Reboxetine (Edronax) (1)

Antidepressants for treating depression in dementia

Sertraline (Lustral) (1)

Antidepressants for treating depression in dementia

Sulpiride (1)

Antidepressants for treating depression in dementia

Epilepsy (0)

Investigational procedures (0)

neuroimaging (0)

rating scales (0)

Malnutrition (1)

Tube feeding (1)

Enteral tube feeding for older people with advanced dementia

Mobility (1)

Driving assessment (1)

Driving assessment for maintaining mobility and safety in drivers with dementia

Mood instability (3)

Anti-psychotic withdrawal (1)

Withdrawal versus continuation of chronic antipsychotic drugs for behavioural and neuropsychiatric symptoms in elderly patients with dementia (protocol stage)

Carbamazepine (1)

Carbamazepine and oxcarbazepine for the treatment of behavioural and psychological symptoms of dementia (BPSD) (protocol stage)

Sexual disinhibition (1)

Antiandrogenic treatment for sexual disinhibition in male patients with dementia (protocol stage)

Psychosis (8)

Anti-psychotic withdrawal (1)

Withdrawal versus continuation of chronic antipsychotic drugs for behavioural and neuropsychiatric symptoms in elderly patients with dementia (protocol stage)

Aripiprazole (1)

Atypical antipsychotics for aggression and psychosis associated with dementia

Carbamazepine (1)

Carbamazepine and oxcarbazepine for the treatment of behavioural and psychological symptoms of dementia (BPSD) (protocol stage)

Clozapine (1)

Atypical antipsychotics for aggression and psychosis associated with dementia

Olanzapine (1)

Atypical antipsychotics for aggression and psychosis associated with dementia

Psychosocial interventions (0)

Quetiapine (1)

Atypical antipsychotics for aggression and psychosis associated with dementia

Risperidone (1)

Atypical antipsychotics for aggression and psychosis associated with dementia

Sulpiride (0)

Thioridazine (1)

Light therapy for managing cognitive, sleep, functional, behavioural, or psychiatric disturbances in dementia

Tiapride (0)

Sleep problems (2)

Alprazolam (Xanax) (0)

Chloral Hydrate (Welldorm) (0)

Chlormethiazole (Heminevrin) (0)

Flurazepam (Dalmane) (0)

Light/photo therapy (1)

Melatonin (1)

Melatonin for the treatment of dementia

Nitrazepam (0)

Psychosocial (0)

Temazepam (0)

Zopiclone (0)

Wandering (3)

Domestic wandering (1)

-Non-pharmacological interventions for wandering of people with dementia in the domestic setting

Music Therapy (1)

Subjective barriers to prevent wandering of cognitively impaired people

Reality orientation (0)

Subjective barriers (1)

Tiapride (0)

Rehabilitation and care (19)

Acupuncture (anxiety, depression, cognition) (1)

Acupuncture for vascular dementia

Art therapy (0)

Audiovisual stimulation (0)

Aquatic therapy (cognition, behavioural problems) (0)

Animal assisted therapy (agitation, well-being, memory function) (0)

Aroma therapy (agitation) (1)

Aroma therapy for dementia

Care management and crisis resolution approaches (0)

Cognitive behavioural therapy (1)

Cognitive reframing for carers of people with dementia (protocol stage)

Cogntive rehabilitation (mood, memory training, wellbeing)) (1)

Cognitive rehabilitation and cognitive training for early-stage Alzheimer's disease and vascular dementia

Cognitive Stimulation (1)

Cognitive stimulation to improve cognitive functioning in people with dementia (protocol stage)

Family counseling (0)

Functional analysis of challenging behaviour (1)

Functional analysis-based interventions for challenging behaviour in dementia (protocol stage)

Home care (0)

Light/Photo therapy (sundowning, sleep, agitation) (1)

Light therapy for managing cognitive, sleep, functional, behavioural, or psychiatric disturbances in dementia

Multidiciplinary team interventions (1)

Multidisciplinary team interventions for delirium in patients with chronic cognitive impairment (withdrawn)

Music Therapy (1)

Physical activity programs for persons with dementia

Occupational therapy (wellbeing, cognition) (0)

Physical restraints (1)

Interventions for preventing and reducing the use of physical restraints in long-term geriatric care (protocol stage)

Physical therapy (1)

Psychosocial therapy (0)

Reminiscence therapy (1)

Reminiscence therapy for dementia

Respite care (1)

Respite care for people with dementia and their carers

Snoezelen (behaviour, mood, cognition, wellbeing) (1)

Snoezelen for dementia

Special Care Units (1)

Special care units for dementia individuals with behavioural problems

Support groups for people with early stage dementia (0)

Telecare and assistive technology (0)

Therapeutic touch (wellbeing, agitation, aggression) (1)

Massage and touch for dementia

Transcutaneous electrical nerve stimulation (TENS) ( cognition, depression, problem behaviour) (1)

Transcutaneous Electrical Nerve Stimulation (TENS) for dementia

Tube feeding (malnutrition, well being,functional state) (1)

Enteral tube feeding for older people with advanced dementia

Validation therapy (aggression, agitation, depression, wellbeing) (1)

Validation therapy for dementia

Delirium (7)

Pharmacological Interventions (4)

Benzodiazepines (1)

Benzodiazepines for delirium

Memantine (0)

Phenothiazines (1)

Acepromazine (0)

Chlorpromazine (0)

Fluphenazine (0)

Mesorodazine (0)

Methotrimeprazine (0)

Perazine (0)

Perphenazine (0)

Promazine (0)

Promethazine (0)

Thioridazine (1)

Antipsychotics for delirium

Trifluoperazine (0)

Triflupromazine (0)

Butyrophenones (0)

Azaperone (0)

Droperidol (0)

Haloperidol (0)

Spiperone (0)

Trifluperidol (0)

Minor thanquilisers (0)

Chlordiazepoxide (0)

Diazepam (0)

Chlormethiazole (0)

Atypical antipsychotics (1)

Cholinesterase inhibitors (1)

Cholinesterase inhibitors for delirium

Non-pharmacological Interventions (3)

Environmental interventions (0)

Multidiscipinary team interventions (3)

Interventions for preventing delirium in hospitalised patients

Multidisciplinary interventions for the management of delirium in hospitalized patients (protocol stage)

Multidisciplinary team interventions for delirium in patients with chronic cognitive impairment (withdrawn)

Oxygen (0)

Diagnosis (0)

Imaging techniques (0)

Other diagnostic tests (0)

Enhancement of normal cognitive function (11)

Acetyl-l-carnitine (fast creative energy) (0)

Adrafinil (alertness without stimulation) (0)

Amphetamines (weight loss and energy) (0)

Bacopa monniera (0)

Caffeine (alertness, well-being and energy) (1)

Caffeine for cognition (protocol stage)

Carbohydrates (1)

Carbohydrates for improving the cognitive performance of independent-living older adults with normal cognition or mild cognitive impairment (protocol stage)

Carnosine (protects against dementia, longivity) (0)

Coenzyme Q (fountain of youth) (0)

Cognitive training (1)

Cognition-based interventions for healthy older people and people with mild cognitive impairment (protocol stage)

Creatine (0)

Dehydroepiandrosterone (DHEA) (1)

Dehydroepiandrosterone (DHEA) supplementation for cognitive function in healthy elderly people

Deprenyl (anti-ageing) (0)

DH3 (memory, concentration and mental endurance) (0)

Diabetes management (1)

Effect of the treatment of Type II diabetes mellitus on the development of cognitive impairment and dementia

Dilantin (intelligence and concentration) (0)

Dimetheyaaminoethanol (DMAE) (brain enhancement) (0)

Folic acid (1)

Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people

Ginkgo biloba (relief side effects of ageing) (1)

Ginkgo biloba for cognitive improvement in healthy individuals (protocol stage)

Gerovital (concentration and vitality) (1)

Hormone replacement therapy for cognitive function in postmenopausal women

Green tea (0)

HRT (1)

Hydergine (intelligence improver) (0)

Hypericum (perception and clear thinking) (0)

Idebenone (cognition and energy enhancement (0)

Liposerine (memory, emotional well-being) (0)

Lucidril (anti-ageing) (0)

Melatonin (anti-ageing) (0)

Modafinil (0)

Nicergoline (clarity and perception) (0)

Omega-3 fish oils (cognition) (1)

Omega 3 fatty acid for the prevention of dementia

Phosphatidyl serine (0)

Picamilone (stimulates without aggression or sedative effect) (0)

Piracetam (intelligence booster) (0)

Pregnonelone (memory enhancement) (0)

Pyritinol (memory, vigilance, concentration) (0)

Pyroglutamic acid (0)

Ritalin (0)

Vinpocetine (memory enhancer) (0)

Xanthinol nicotinate (reaction speed, memory) (0)

Physical activity (1)

Physical activity and enhanced fitness to improve cognitive function in older people without known cognitive impairment

Prevention of dementia (29)

Cognitively impaired (17)

Non-pharmacological interventions (2)

Acupuncture (0)

Cognitive training (1)

Cognition-based interventions for healthy older people and people with mild cognitive impairment (protocol stage)

Diabetes managament (1)

Effect of the treatment of Type II diabetes mellitus on the development of cognitive impairment and dementia

Physical activity (0)

Prevention trials (0)

Pharmacological interventions (15)

Diabetes management (1)

Effect of the treatment of Type II diabetes mellitus on the development of cognitive impairment and dementia

Donepezil (1)

Donepezil for mild cognitive impairment

Folic acid (1)

Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people

Galantamine (2)

Galantamine for Alzheimer's disease and mild cognitive impairment

Galantamine for vascular cognitive impairment

Gingko biloba (1)

Ginkgo biloba for cognitive impairment and dementia

Lecithin (1)

Lecithin for dementia and cognitive impairment

Melatonin (1)

Melatonin for the treatment of dementia

Nicergoline (1)

Nicergoline for dementia and other age associated forms of cognitive impairment

Piracetam (1)

Piracetam for dementia or cognitive impairment

Prevention trials (0)

Procaine (Gerovital) (1)

Vinpocetine for cognitive impairment and dementia

Rivastigmine (0)

Vinpocetine (1)

Vitamin B12 (1)

Vitamin B12 for cognition

Vitamin B6 (1)

Vitamin B6 for cognition

Vitamin E (1)

Vitamin E for Alzheimer's disease and mild cognitive impairment

Non-cognitively impaired (12)

Non-pharmacological interventions (3)

Cognitive training (1)

Cognition-based interventions for healthy older people and people with mild cognitive impairment (protocol stage)

Diabetes management (1)

Effect of the treatment of Type II diabetes mellitus on the development of cognitive impairment and dementia

Diet and lifestyle (1)

Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia

Massage and touch (0)

Physical activity (0)

Prevention trials (0)

Pharmacological interventions (9)

Acetyl-l-carnitine (0)

Anti-hypertensives (1)

Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia

Aspirin and NSAIDs (0)

Dehydroepiandrosterone (DHEA) (1)

Dehydroepiandrosterone (DHEA) supplementation for cognitive function in healthy elderly people

Diabetes management (1)

Effect of the treatment of Type II diabetes mellitus on the development of cognitive impairment and dementia

Donepezil (0)

Folic acid (1)

Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people

Galantamine (0)

HRT (1)

Hormone replacement therapy for cognitive function in postmenopausal women

Omega-3 fish oil (1)

Omega 3 fatty acid for the prevention of dementia

Prevention trials (0)

Procaine (Gerovital) (1)