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Anaesthesia Group (152)
AMBULATORY ANAESTHESIA (4)
Anaesthesia for cardioversion (1)
Anaesthesia for cardioversion (protocol stage)
Anaesthesia for electroconvulsive therapy (0)
Other interventions (3)
Sedative techniques for endoscopic retrograde cholangiopancreatography (protocol stage)
Topical anaesthesia for nasogastric tube insertion (protocol stage)
Topical anaesthetics for repair of dermal laceration (protocol stage)
ANAESTHESIA AND MEDICAL DISEASES (7)
Perioperative events (4)
Neuraxial anaesthesia for lower-limb revascularization (protocol stage)
Non-pharmacological interventions for assisting the induction of anaesthesia in children
Perioperative increase in global blood flow to explicit defined goals and outcomes following surgery (protocol stage)
Pharmacologic therapies for perioperative cerebral protection against neurologic or neurocognitive deficits (protocol stage)
Preoperative evaluation (0)
Preoperative treatment (3)
Cardiovascular disease (1)
Alpha-2 adrenergic agonists for the prevention of cardiac complications among patients undergoing surgery
Endocrinological disease (1)
Glucose-insulin-potassium (GIK) and Tight-glycaemic-control (TGC) versus standard therapy insulin for critically ill patients (protocol stage)
Malignant hyperpyrexia (0)
Muscular disorders (0)
Neurological disease (0)
Pulmonary disease (0)
Other diseases (1)
Perioperative beta-blockers for preventing surgery related mortality and morbidity (protocol stage)
DRUGS IN ANAESTHESIA AND INTENSIVE CARE MEDICINE (25)
Intravenous anaesthetics (5)
Deliberate hypotension with propofol under anaesthesia for functional endoscopic sinus surgery (FESS) (protocol stage)
Intravenous versus inhalation anaesthesia for one-lung ventilation
Physicopharmacological interventions for reducing propofol-induced pain on induction of anaesthesia in adults (protocol stage)
Sedative techniques for endoscopic retrograde cholangiopancreatography (protocol stage)
Target-controlled infusion versus manually-controlled infusion of propofol for general anaesthesia or sedation in adults
Neuromuscular blocking agents (2)
Rocuronium versus succinylcholine for rapid sequence induction intubation
Sugammadex, a selective reversal medication for preventing postoperative residual neuromuscular blockade
Opioids (0)
Premedication (2)
Music for preoperative anxiety (protocol stage)
Premedication for anxiety in adult day surgery
Sedatives (3)
Analgo-sedation for diagnostic and therapeutic endoscopic or radiologic procedures in adults (protocol stage)
Music for preoperative anxiety (protocol stage)
Remifentanil for analgesia and sedation of critically ill patients in intensive care units (protocol stage)
Volatile anaesthetics (3)
Deliberate hypotension with propofol under anaesthesia for functional endoscopic sinus surgery (FESS) (protocol stage)
High concentration versus low concentration sevoflurane for anaesthesia induction (protocol stage)
Sevoflurane versus other general anaesthesia on postoperative behaviour disturbance in children (protocol stage)
Other drugs (10)
Adjusting the pH of lidocaine for reducing pain on injection (protocol stage)
Aerosolized prostacyclin for acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) (protocol stage)
Anaesthetic interventions for prevention of awareness during surgery (protocol stage)
Antifibrinolytic agents for reducing blood loss in scoliosis surgery in children
Glucose-insulin-potassium (GIK) and Tight-glycaemic-control (TGC) versus standard therapy insulin for critically ill patients (protocol stage)
Intensive insulin therapy and strict glucose control for critically ill patients (protocol stage)
Interventions for restoring patency of occluded central venous catheter lumens (protocol stage)
Lidocaine for preventing postoperative sore throat
Non-steroidal anti-inflammatory drugs and perioperative bleeding in paediatric tonsillectomy
Supplemental perioperative steroids for surgical patients with adrenal insufficiency
MISCELLANEOUS (0)
PERIANAESTHETIC / PERIOPERATIVE CARE MEDICINE (31)
Acute postoperative pain (3)
Caudal epidural block versus other methods of postoperative pain relief for circumcision in boys
Continuous interscalene blockade versus parenteral analgesia for postoperative pain relief after major shoulder surgery (protocol stage)
Patient controlled intravenous opioid analgesia versus continuous epidural analgesia for pain after intra-abdominal surgery
Fluid management (7)
Crystalloids/colloids/blood component therapy (7)
Antifibrinolytic agents for reducing blood loss in scoliosis surgery in children
Colloid versus crystalloid solutions for priming cardiopulmonary bypass circuits (protocol stage)
Hypertonic saline for peri-operative fluid management (protocol stage)
Interventions for protecting renal function in the perioperative period
Perioperative buffered versus non-buffered fluid administration for surgery in adults (protocol stage)
Perioperative fluid volume optimization following proximal femoral fracture
Thrombelastography (TEG) or Thrombelastometry (ROTEM) to monitor haemotherapy versus usual care in patients with massive transfusion (protocol stage)
Perioperative management of the anaesthetic patient (14)
Adjusting the pH of lidocaine for reducing pain on injection (protocol stage)
Cooling for cerebral protection during brain surgery (protocol stage)
Deliberate hypotension with propofol under anaesthesia for functional endoscopic sinus surgery (FESS) (protocol stage)
Early extubation for adult cardiac surgical patients
Early versus late removal of laryngeal mask airway (LMA) for general anaesthesia (protocol stage)
Epidural analgesia for cardiac surgery (protocol stage)
High concentration versus low concentration sevoflurane for anaesthesia induction (protocol stage)
Laryngeal mask airway versus endotracheal tube in laparoscopic cholecystectomy in adults (protocol stage)
Laryngeal mask airway versus endotracheal tube in laparoscopic gynaecological surgery in adults (protocol stage)
Local anaesthetics and regional anaesthesia for preventing chronic pain after surgery (protocol stage)
Positive end-expiratory pressure (PEEP) during anaesthesia for the prevention of mortality and postoperative pulmonary complications (protocol stage)
Sedation versus general anaesthesia for provision of dental treatment in under 18 year olds
Thrombelastography (TEG) or Thrombelastometry (ROTEM) to monitor haemotherapy versus usual care in patients with massive transfusion (protocol stage)
Traditional landmark versus ultrasound guidance for central vein catheterization (protocol stage)
Perioperative nutrition (1)
Prescribed hypocaloric nutrition support for critically ill adults (protocol stage)
Postoperative complications (6)
Nausea and vomiting (3)
Aromatherapy for treatment of postoperative nausea and vomiting (protocol stage)
Drugs for preventing postoperative nausea and vomiting
Stimulation of the wrist acupuncture point P6 for preventing postoperative nausea and vomiting
Other complications (3)
Drugs for the prevention and treatment of pruritus in patients receiving neuraxial opioids (protocol stage)
Positive end-expiratory pressure (PEEP) during anaesthesia for the prevention of mortality and postoperative pulmonary complications (protocol stage)
Sevoflurane versus other general anaesthesia on postoperative behaviour disturbance in children (protocol stage)
POSTANAESTHETIC UNIT / INTENSIVE CARE UNIT (51)
Circulatory care (11)
Fluid therapy (2)
Adrenaline (epinephrine) for the treatment of anaphylaxis with and without shock
Catheter impregnation, coating or bonding for reducing central venous catheter related infections in adults (protocol stage)
Haemodynamic management (4)
Central venous access sites for the prevention of venous thrombosis, stenosis and infection in patients requiring long-term intravenous therapy
Heparin versus normal saline for patency of arterial lines (protocol stage)
Pharmacological agents for preventing morbidity associated with the haemodynamic response to tracheal intubation (protocol stage)
Pulmonary artery catheters for adult patients in intensive care
Nutrition (4)
Enteral nutritional supplementation with arginine for critically ill patients (protocol stage)
Nutritional support for critically ill children
Prescribed hypocaloric nutrition support for critically ill adults (protocol stage)
Selenium supplementation for critically ill adults
Vasopressors (1)
Vasopressors for shock
Volume resuscitation (0)
Infection control (16)
Adjunctive hyperbaric oxygen for necrotizing fasciitis (protocol stage)
Antibiotic prophylaxis for surgical introduction of intracranial ventricular shunts
Antifungal agents for preventing fungal infections in non-neutropenic critically ill patients
Antithrombin III for critically ill patients
Beta lactam antibiotic monotherapy versus beta lactam-aminoglycoside antibiotic combination therapy for sepsis
Catheter impregnation, coating or bonding for reducing central venous catheter related infections in adults (protocol stage)
Cefepime versus other beta-lactam antibiotics for the treatment of infections in non-neutropenic patients (protocol stage)
Corticosteroids for treating severe sepsis and septic shock
De-escalation of antimicrobial treatment for adults with sepsis, severe sepsis or septic shock (protocol stage)
Early versus late pre-intensive care unit admission broad spectrum antibiotics for severe sepsis in adults (protocol stage)
High-volume haemofiltration for sepsis (protocol stage)
Human recombinant activated protein C for severe sepsis
Interventions for restoring patency of occluded central venous catheter lumens (protocol stage)
Intravenous immunoglobulin for treating sepsis, severe sepsis and septic shock
N-acetylcysteine for sepsis and systemic inflammatory response in adults (protocol stage)
Optimal timing for intravenous administration set replacement
Metabolism (0)
Positioning (2)
Lateral positioning for critically ill adult patients (protocol stage)
Prone position for acute respiratory failure in adults (protocol stage)
Respiratory care (22)
Mechanical ventilation (6)
Aerosolized prostacyclin for acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) (protocol stage)
Early versus late tracheostomy for critically ill patients (protocol stage)
Music interventions for mechanically ventilated patients (protocol stage)
Prone position for acute respiratory failure in adults (protocol stage)
Protocolized versus non-protocolized weaning for reducing the duration of mechanical ventilation in critically ill adult patients (protocol stage)
Recruitment manoeuvres for adults with acute lung injury receiving mechanical ventilation
Other ventilatory support (16)
Closed tracheal suction systems versus open tracheal suction systems for mechanically ventilated adult patients
Early versus late tracheostomy for critically ill patients (protocol stage)
Heated humidification versus heat and moisture exchangers for ventilated adults and children (protocol stage)
High-frequency ventilation versus conventional ventilation for treatment of acute lung injury and acute respiratory distress syndrome
Incentive spirometry for prevention of postoperative pulmonary complications in upper abdominal surgery
Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) and acute lung injury in children and adults
Inhaled nitric oxide for the postoperative management of pulmonary hypertension in infants and children with congenital heart disease
Lung protective ventilation strategy for the acute respiratory distress syndrome
Noninvasive positive pressure ventilation as a weaning strategy for intubated adults with respiratory failure
Partial liquid ventilation for preventing death and morbidity in adults with acute lung injury and acute respiratory distress syndrome
Partial liquid ventilation for the prevention of mortality and morbidity in paediatric acute lung injury and acute respiratory distress syndrome
Percutaneous technique versus surgical techniques for tracheostomy (protocol stage)
Pharmacologic therapies for adults with acute lung injury and acute respiratory distress syndrome
Preoxygenation for tracheal suctioning in ventilated adults (protocol stage)
Pressure support versus T tube for weaning from mechanical ventilation in adults (protocol stage)
Recruitment manoeuvres for adults with acute lung injury receiving mechanical ventilation
PREHOSPITAL MEDICINE / RESUSCITATION / EMERGENCY MEDICINE (12)
Acute medical conditions (2)
Adjunctive hyperbaric oxygen for necrotizing fasciitis (protocol stage)
Glucocorticoids for the treatment of anaphylaxis (protocol stage)
Anaesthesia (1)
Cooling for cerebral protection during brain surgery (protocol stage)
Cardiopulmonary resuscitation (1)
Hypothermia for neuroprotection in adults after cardiopulmonary resuscitation
Emergency medicine (8)
Adrenaline (epinephrine) for the treatment of anaphylaxis with and without shock
Early versus late pre-intensive care unit admission broad spectrum antibiotics for severe sepsis in adults (protocol stage)
Glucocorticoids for the treatment of anaphylaxis (protocol stage)
H1-antihistamines for the treatment of anaphylaxis with and without shock
Recompression and adjunctive therapy for decompression illness
Simple aspiration versus intercostal tube drainage for primary spontaneous pneumothorax in adults
The use of propofol for procedural sedation in emergency departments (protocol stage)
Topical anaesthesia for nasogastric tube insertion (protocol stage)
Initial cardiopulmonary stabilisation (0)
REGIONAL ANAESTHESIA (18)
Epidural blocks (3)
Epidural analgesia for cardiac surgery (protocol stage)
Epidural pain relief versus systemic opioid-based pain relief for abdominal aortic surgery
Use of hyperbaric versus isobaric bupivacaine for spinal anaesthesia for caesarean section (protocol stage)
Intravenous/arterial regional anaesthesia (3)
Infraclavicular brachial plexus block for regional anaesthesia of the lower arm (protocol stage)
Intra-articular lignocaine versus intravenous analgesia with or without sedation for manual reduction of acute anterior shoulder dislocation in adults (protocol stage)
Ultrasound guidance for peripheral nerve blockade
Peripheral nerve blocks (2)
Peribulbar versus retrobulbar anaesthesia for cataract surgery
Single, double or multiple injection techniques for axillary brachial plexus block for hand, wrist or forearm surgery
Pharmacology in regional anaesthesia (1)
Local anaesthetics and regional anaesthesia for preventing chronic pain after surgery (protocol stage)
Spinal anaesthesia (2)
Interventions for preventing hypotension in adults receiving spinal anaesthesia (protocol stage)
Transient neurologic symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics
Other interventions (7)
Continuous interscalene blockade versus parenteral analgesia for postoperative pain relief after major shoulder surgery (protocol stage)
Drugs for the prevention and treatment of pruritus in patients receiving neuraxial opioids (protocol stage)
Injectable local anaesthetic agents for operative dental anaesthesia (protocol stage)
Paracervical local anaesthesia for cervical dilatation and uterine intervention
Sub-Tenon's anaesthesia versus topical anaesthesia for cataract surgery
Supplemental oxygen for caesarean section during regional anaesthesia (protocol stage)
Topical anaesthesia alone versus topical anaesthesia with intracameral lidocaine for phacoemulsification
TECHNOLOGY IN ANAESTHESIA (4)
Equipment (4)
Anaesthetic apparatus/monitoring system (4)
Anaesthetic interventions for prevention of awareness during surgery (protocol stage)
Bispectral index for improving anaesthetic delivery and postoperative recovery
Heparin versus normal saline for patency of arterial lines (protocol stage)
Pulse oximetry for perioperative monitoring