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Airways Group (268)
Chronic asthma - pharmacological interventions (82)
Inhaled or intranasal steroids (20)
Beclomethasone at different doses for chronic asthma
Beclomethasone for asthma in children: effects on linear growth
Beclomethasone versus budesonide for chronic asthma
Beclomethasone versus placebo for chronic asthma
Budesonide at different doses for chronic asthma
Budesonide versus placebo for chronic asthma in children and adults
Ciclesonide versus other inhaled steroids for chronic asthma in children and adults
Ciclesonide versus placebo for chronic asthma in adults and children
Fluticasone at different doses for chronic asthma in adults and children
Fluticasone versus 'extrafine' HFA-beclomethasone dipropionate for chronic asthma in adults and children
Fluticasone versus beclomethasone or budesonide for chronic asthma in adults and children
Fluticasone versus placebo for chronic asthma in adults and children
High dose versus low dose inhaled corticosteroid as initial starting dose for asthma in adults and children
Holding chambers versus nebulisers for inhaled steroids in chronic asthma
Inhaled and oral corticosteroids as maintenance and intermittent therapy for episodic viral wheeze in children
Inhaled corticosteroid effects on bone metabolism in asthma and mild chronic obstructive pulmonary disease
Inhaled versus oral steroids for adults with chronic asthma
Intranasal corticosteroids for asthma control in people with coexisting asthma and rhinitis
Mometasone for asthma in adults and children (protocol stage)
Triamcinolone for chronic asthma (protocol stage) (withdrawn)
Non-steroidal preventer therapy (5)
Inhaled corticosteroids versus sodium cromoglycate in children and adults with asthma
Inhaled sodium cromoglycate for asthma in children
Ketotifen alone or as additional medication for long-term control of asthma and wheeze in children
Nedocromil sodium for chronic asthma in children
Nedocromil sodium for preventing exercise-induced bronchoconstriction
Bronchodilator therapy (19)
Addition of inhaled long-acting beta2-agonists to inhaled steroids as first line therapy for persistent asthma in steroid-naive adults and children
Anticholinergic agents for chronic asthma in adults
Anticholinergic drugs for wheeze in children under the age of two years
Anticholinergic therapy for chronic asthma in children over two years of age
Caffeine for asthma
Inhaled short acting beta2-agonist use in chronic asthma: regular versus as needed treatment
Long-acting beta2-agonists as an inhaled corticosteroid-sparing agent for chronic asthma in adults and children
Long-acting beta2-agonists for chronic asthma in adults and children where background therapy contains varied or no inhaled corticosteroid
Long-acting beta2-agonists versus anti-leukotrienes as add-on therapy to inhaled corticosteroids for chronic asthma
Long-acting beta2-agonists versus placebo in addition to inhaled corticosteroids in adults and children with chronic asthma
Long-acting beta2-agonists versus theophylline for maintenance treatment of asthma
Oral theophylline for stable asthma in adults (protocol stage) (withdrawn)
Oral xanthines as maintenance treatment for asthma in children
Pressurised metered dose inhalers versus all other hand-held inhaler devices to deliver beta-2 agonist bronchodilators for non-acute asthma
Regular treatment with formoterol for chronic asthma: serious adverse events
Regular treatment with formoterol versus regular treatment with salmeterol for chronic asthma: serious adverse events
Regular treatment with long acting beta agonists versus daily regular treatment with short acting beta agonists in adults and children with stable asthma
Regular treatment with salmeterol for chronic asthma: serious adverse events
Short acting beta2-agonists for recurrent wheeze in children under two years of age
Steroid sparing agents (10)
Anti-IgE for chronic asthma in adults and children
Azathioprine as an oral corticosteroid sparing agent for asthma
Chloroquine as a steroid sparing agent for asthma
Colchicine as an oral corticosteroid sparing agent for asthma
Cyclosporin as an oral corticosteroid sparing agent in stable asthma
Dapsone as an oral corticosteroid sparing agent for asthma
Gold as an oral corticosteroid sparing agent in stable asthma
Long-acting beta2-agonists as an inhaled corticosteroid-sparing agent for chronic asthma in adults and children
Methotrexate as an oral corticosteroid sparing agent for asthma in adults
Troleandomycin as an oral corticosteroid sparing agent in stable asthma
Combination and additive therapies (14)
Addition of anti-leukotriene agents to inhaled corticosteroids for chronic asthma
Addition of inhaled long-acting beta2-agonists to inhaled steroids as first line therapy for persistent asthma in steroid-naive adults and children
Addition of long-acting beta-agonists to inhaled corticosteroids for chronic asthma in children
Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children
Combination fluticasone and salmeterol versus fixed dose combination budesonide and formoterol for chronic asthma in adults and children
Combination formoterol and budesonide as maintenance and reliever therapy versus inhaled steroid maintenance for chronic asthma in adults and children
Combination formoterol and inhaled steroid versus beta2-agonist as relief medication for chronic asthma in adults and children
Combination of inhaled long-acting beta2-agonists and inhaled steroids versus higher dose of inhaled steroids in children and adults with persistent asthma
Long-acting beta2-agonists versus anti-leukotrienes as add-on therapy to inhaled corticosteroids for chronic asthma
Long-acting beta2-agonists versus placebo in addition to inhaled corticosteroids in adults and children with chronic asthma
Regular fixed-dose treatment with formoterol and inhaled corticosteroids versus regular treatment with salmeterol and inhaled corticosteroids for chronic asthma: serious adverse events (protocol stage)
Regular treatment with formoterol and inhaled steroids for chronic asthma: serious adverse events
Regular treatment with salmeterol and inhaled steroids for chronic asthma: serious adverse events
Single versus multiple inhalers for the administration of corticosteroid and long-acting beta-agonists in chronic asthma (protocol stage)
Delivery of inhaled therapy (4)
Nebulisers versus hand-held inhalers to deliver beta2-agonist bronchodilator drugs in non-acute asthma (protocol stage)
Pressurised metered dose inhalers versus all other hand-held inhaler devices to deliver beta-2 agonist bronchodilators for non-acute asthma
Pressurised-metered dose inhalers versus other hand-held inhalation devices for the delivery of inhaled corticosteroid therapy in children with non-acute asthma (protocol stage)
Pressurised-metred does inhalers versus hand-held inhalers for the delivery of corticosteroids in adults with asthma (protocol stage)
Vaccines (2)
Pneumococcal vaccine for asthma
Vaccines for preventing influenza in people with asthma
Gastro-oesophogeal reflux treatment (1)
Gastro-oesophageal reflux treatment for asthma in adults and children
Antibody and immunotherapy (2)
Allergen immunotherapy for asthma
Anti-IgE for chronic asthma in adults and children
Other (5)
Azoles for allergic bronchopulmonary aspergillosis associated with asthma
Cardioselective beta-blockers for reversible airway disease
Macrolides for chronic asthma
Oxatomide for stable asthma in adults and children
Phosphodiasterase III inhibitors for chronic asthma (protocol stage)
Chronic asthma - non-pharmacological interventions (41)
Self-management, written action plans and education (11)
Culture-specific programs for children and adults from minority groups who have asthma
Educational interventions for asthma in children
Indigenous healthcare worker involvement for Indigenous adults and children with asthma
Limited (information only) patient education programs for adults with asthma
Options for self-management education for adults with asthma
Self-management education and regular practitioner review for adults with asthma
Tailored interventions based on exhaled nitric oxide versus clinical symptoms for asthma in children and adults
Tailored interventions based on sputum eosinophils versus clinical symptoms for asthma in children and adults
Telehealthcare for asthma (protocol stage)
Written action plans for asthma in children
Written individualised management plans for asthma in children and adults
Psychotherapeutic interventions (4)
Family therapy for asthma in children
Psychological interventions for adults with asthma
Psychological interventions for children with asthma
Written emotional disclosure for asthma (protocol stage)
Breathing, posture, physical and exercise training (5)
Alexander technique for chronic asthma
Breathing exercises for asthma
Inspiratory muscle training for asthma
Manual therapy for asthma
Physical training for asthma
Dietary manipulation (8)
Calorie controlled diet for chronic asthma
Cow's milk protein avoidance and development of childhood wheeze in children with a family history of atopy (withdrawn)
Dietary marine fatty acids (fish oil) for asthma in adults and children
Dietary salt reduction or exclusion for allergic asthma
Monosodium glutamate avoidance for chronic asthma in adults and children (protocol stage)
Selenium supplementation for asthma
Tartrazine exclusion for allergic asthma
Vitamin C supplementation for asthma
Acupuncture, homoeopathy and herbal remedies (3)
Acupuncture for chronic asthma
Herbal interventions for chronic asthma in adults and children
Homeopathy for chronic asthma
Environmental interventions (9)
Feather versus non-feather bedding for asthma
House dust mite control measures for asthma
Humidification of inspired air in exercise-induced asthma (protocol stage)
Humidity control for chronic asthma
Ionisers for chronic asthma
Mono and multifaceted inhalant and/or food allergen reduction interventions for preventing asthma in children at high risk of developing asthma
Pet allergen control measures for allergic asthma in children and adults
Speleotherapy for asthma
Workplace interventions for treatment of occupational asthma (protocol stage)
Delivery of care (1)
Primary care based clinics for asthma
Exercise induced-bronchoconstriction (6)
Beta-2 agonists for exercise induced asthma (protocol stage)
Humidification of inspired air in exercise-induced asthma (protocol stage)
Inhaled corticosteroids compared to placebo for prevention of exercise induced bronchoconstriction
Mast-cell stabilising agents to prevent exercise-induced bronchoconstriction
Nedocromil sodium for preventing exercise-induced bronchoconstriction
Nedocromil sodium versus sodium cromoglycate for preventing exercise-induced bronchoconstriction
Acute asthma - pharmacological interventions (24)
Steroids (9)
Corticosteroids for acute severe asthma in hospitalised patients
Corticosteroids for hospitalised children with acute asthma
Corticosteroids for preventing relapse following acute exacerbations of asthma
Early emergency department treatment of acute asthma with systemic corticosteroids
Early use of inhaled corticosteroids in the emergency department treatment of acute asthma
Increased versus stable doses of inhaled steroids for exacerbations of chronic asthma in adults and children (protocol stage)
Inhaled steroids for acute asthma following emergency department discharge
Oral and systemic steroids at different doses for acute asthma in hospitalised children (protocol stage)
Parent-initiated oral corticosteroid therapy for intermittent wheezing illnesses in children
Bronchodilator therapy (11)
Addition of intravenous aminophylline to beta2-agonists in adults with acute asthma
Anticholinergic therapy for acute asthma in children (protocol stage)
Combined inhaled anticholinergics and beta2-agonists for initial treatment of acute asthma in children
Combined inhaled beta-agonist and anticholinergic agents in the emergency management of adult asthmatic patients (protocol stage)
Commercial versus home-made spacers in delivering bronchodilator therapy for acute therapy in children
Continuous versus intermittent beta-agonists for acute asthma
Heliox for non-intubated acute asthma patients
Holding chambers (spacers) versus nebulisers for beta-agonist treatment of acute asthma
Inhaled beta2-agonists for asthma in mechanically ventilated patients
Intravenous aminophylline for acute severe asthma in children over two years receiving inhaled bronchodilators
Intravenous beta2-agonists for acute asthma in the emergency department
Other (4)
Antibiotics for acute asthma
Inhaled magnesium sulfate in the treatment of acute asthma
Leucotriene receptor antagonists in addition to usual care for acute asthma in adults and children (protocol stage)
Magnesium sulfate for treating exacerbations of acute asthma in the emergency department
Acute asthma - non-pharmacological interventions (4)
Ventilation (2)
Non-invasive positive pressure ventilation for treatment of respiratory failure due to severe acute exacerbations of asthma
Oxygen versus air for nebulising beta-agonist bronchodilators in acute asthma (protocol stage)
Education (2)
Education interventions for adults who attend the emergency room for acute asthma
Interventions for educating children who are at risk of asthma-related emergency department attendance
Stable chronic obstructive pulmonary disease - pharmacological interventions (24)
Corticosteroid therapy (3)
Combined corticosteroid and long-acting beta-agonist in one inhaler versus placebo for chronic obstructive pulmonary disease
Inhaled corticosteroids for stable chronic obstructive pulmonary disease
Oral corticosteroids for stable chronic obstructive pulmonary disease
Bronchodilator therapy (10)
Inhaled corticosteroids versus long acting beta-agonists for chronic obstructive pulmonary disease (protocol stage)
Ipratropium bromide for stable chronic obstructive pulmonary disease (protocol stage)
Ipratropium bromide versus long-acting beta-2 agonists for stable chronic obstructive pulmonary disease
Ipratropium bromide versus short acting beta-2 agonists for stable chronic obstructive pulmonary disease
Long-acting beta2-agonists for chronic obstructive pulmonary disease: serious adverse events (protocol stage)
Long-acting beta2-agonists for poorly reversible chronic obstructive pulmonary disease
Nebulisers versus all hand-held inhalers to deliver bronchodilators in chronic obstructive pulmonary disease (protocol stage)
Oral theophylline for chronic obstructive pulmonary disease
Short-acting beta2-agonists for stable chronic obstructive pulmonary disease
Tiotropium for stable chronic obstructive pulmonary disease
Antibiotic therapy (1)
Prophylactic antibiotic therapy for chronic bronchitis
Combination therapy (4)
Combination inhaled steroid and long-acting beta-agonist versus tiotropium for chronic obstructive pulmonary disease (protocol stage)
Combined corticosteroid and long-acting beta-agonist in one inhaler versus inhaled steroids for chronic obstructive pulmonary disease
Combined corticosteroid and long-acting beta-agonist in one inhaler versus long-acting beta-agonists for chronic obstructive pulmonary disease
Combined corticosteroid and long-acting beta-agonist in one inhaler versus placebo for chronic obstructive pulmonary disease
Vaccines (2)
Influenza vaccine for patients with chronic obstructive pulmonary disease
Injectable vaccines for preventing pneumococcal infection in patients with chronic obstructive pulmonary disease
Delivery of inhaled therapy (1)
Pressurised metered-dose inhalers versus all other hand-held inhalers devices to deliver bronchodilators for chronic obstructive pulmonary disease
Other (3)
Cardioselective beta-blockers for chronic obstructive pulmonary disease
Mucolytic agents for chronic bronchitis or chronic obstructive pulmonary disease
Phosphodiesterase 4 inhibitors for chronic obstructive pulmonary disease (protocol stage)
Stable chronic obstructive pulmonary disease - non-pharmacological interventions (19)
Self-management, written action plans, lifestyle and education (5)
Action plans for chronic obstructive pulmonary disease
Nutritional supplementation for stable chronic obstructive pulmonary disease
Self-management education for patients with chronic obstructive pulmonary disease
Smoking cessation for chronic obstructive pulmonary disease
Telehealthcare for chronic obstructive pulmonary disease (protocol stage)
Breathing, physiotherapy and exercise therapy (7)
Bronchopulmonary hygiene physical therapy for chronic obstructive pulmonary disease and bronchiectasis
Intensity and type of exercise for lower limb endurance training to optimise exercise capacity for people with chronic obstructive pulmonary disease (protocol stage)
Interventions for adherence to pulmonary rehabilitation for chronic obstructive pulmonary disease (protocol stage)
Non-invasive ventilation during exercise training for people with chronic obstructive pulmonary disease (protocol stage)
Oxygen therapy during exercise training in chronic obstructive pulmonary disease
Pulmonary rehabilitation for chronic obstructive pulmonary disease
Supervised physical exercise training for chronic obstructive pulmonary disease: long-term efficacy and safety (protocol stage)
Oxygen therapy (5)
Ambulatory oxygen for chronic obstructive pulmonary disease
Domiciliary oxygen for chronic obstructive pulmonary disease
Nocturnal non-invasive positive pressure ventilation for stable chronic obstructive pulmonary disease
Palliative oxygen for non-hypoxaemic chronic obstructive pulmonary disease (protocol stage)
Short-term ambulatory oxygen for chronic obstructive pulmonary disease
Surgery (1)
Lung volume reduction surgery for diffuse emphysema
Other (1)
Home care by outreach nursing for chronic obstructive pulmonary disease
Exacerbations of chronic obstructive pulmonary disease (11)
Corticosteroid therapy (1)
Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease
Bronchodilator therapy (4)
Anticholinergic bronchodilators versus beta2-sympathomimetic agents for acute exacerbations of chronic obstructive pulmonary disease
Heliox for treatment of exacerbations of chronic obstructive pulmonary disease
Inhaled short-acting beta2-agonists versus ipratropium for acute exacerbations of chronic obstructive pulmonary disease
Methylxanthines for exacerbations of chronic obstructive pulmonary disease
Pulmonary rehabilitation (1)
Pulmonary rehabilitation following exacerbations of chronic obstructive pulmonary disease
Ventilation (2)
Non-invasive positive pressure ventilation for treatment of respiratory failure due to exacerbations of chronic obstructive pulmonary disease
Oxygen therapy in the pre-hospital setting for acute exacerbations of chronic obstructive pulmonary disease
Delivery of care (1)
Hospital at home for acute exacerbations of chronic obstructive pulmonary disease
Other (2)
Carbonic anhydrase inhibitors for hypercapnic ventilatory failure in chronic obstructive pulmonary disease
Doxapram for ventilatory failure due to exacerbations of chronic obstructive pulmonary disease
Chronic cough (12)
Anti-histamines for prolonged non-specific cough in children
Antibiotics for prolonged moist cough in children
Anticholinergics for prolonged non-specific cough in children
Clinical pathways for chronic cough in children
Gastro-oesophageal reflux treatment for prolonged non-specific cough in children and adults
Honey and lozenges for children with non-specific cough
Indoor air modification interventions for prolonged non-specific cough in children
Inhaled beta2-agonists for non-specific chronic cough in children
Inhaled corticosteroids for non-specific chronic cough in children
Inhaled cromones for prolonged non-specific cough in children
Leukotriene receptor antagonist for prolonged non-specific cough in children
Methylxanthines for prolonged non-specific cough in children
Bronchiectasis, sarcoidosis and interstitial lung disease (26)
Anticholinergic therapy for bronchiectasis
Bronchopulmonary hygiene physical therapy for chronic obstructive pulmonary disease and bronchiectasis
Corticosteroids for idiopathic pulmonary fibrosis
Corticosteroids for pulmonary sarcoidosis
Cyclophosphamide for interstitial lung disease (protocol stage)
Domiciliary oxygen for interstitial lung disease
Immunomodulatory agents for idiopathic pulmonary fibrosis
Immunosuppressive and cytotoxic therapy for pulmonary sarcoidosis
Influenza vaccine for children and adults with bronchiectasis
Inhaled hyperosmolar agents for bronchiectasis
Inhaled steroids for bronchiectasis
Leukotriene receptor antagonists for non-cystic fibrosis bronchiectasis
Long-acting beta2-agonists for bronchiectasis
Mucolytics for bronchiectasis
Nebulised morphine for severe interstitial lung disease
Nurse specialist care for bronchiectasis
Oral methylxanthines for bronchiectasis
Oral non steroid anti-inflammatories for children and adults with bronchiectasis
Oral steroids for bronchiectasis (stable and acute exacerbations)
Physical training for bronchiectasis
Physical training for interstitial lung disease
Pneumococcal vaccines for children and adults with bronchiectasis
Prolonged antibiotics for purulent bronchiectasis in children and adults
Short acting beta2-agonists for bronchiectasis
Singing for children and adults with bronchiectasis (protocol stage)
Surgery versus non-surgical treatment for bronchiectasis
Sleep apnoea (10)
Continuous positive airways pressure (4)
Continuous positive airway pressure delivery interfaces for obstructive sleep apnoea
Continuous positive airways pressure for obstructive sleep apnoea in adults
Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines for adults with obstructive sleep apnoea
Pressure modification for improving usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea
Oral appliance therapy (1)
Oral appliances for obstructive sleep apnoea
Drug treatment (2)
Anti-inflammatory medications for obstructive sleep apnea in children (protocol stage)
Drug therapy for obstructive sleep apnoea in adults
Lifestyle modification (1)
Lifestyle modification for obstructive sleep apnoea
Surgery (2)
Adenotonsillectomy for obstructive sleep apnoea in children
Surgery for obstructive sleep apnoea in adults
Oxygen (0)
Pulmonary hypertension (3)
Endothelin receptor antagonists for pulmonary arterial hypertension
Phosphodiesterase five inhibitors for pulmonary hypertension
Prostacyclin for pulmonary hypertension in adults
Other (6)
Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults
Galactomannan detection for invasive aspergillosis in immunocompromized patients
Inhaled steroids for neonatal chronic lung disease
Interventions for primary (intrinsic) tracheomalacia in children
Intra-pleural fibrinolytic therapy versus conservative management in the treatment of adult parapneumonic effusions and empyema
Restriction of oral intake of water for aspiration lung disease in children