5-FU for genital warts in non-immunocompromised individuals (protocol stage)

Absorbable versus non-absorbable sutures for primary closure of traumatic lacerations and surgical wounds (protocol stage)

Acamprosate for alcohol dependence (protocol stage)

Acetylcholinesterase inhibitors for schizophrenia (protocol stage)

Acetylsalicylic acid (Aspirin) for primary prevention of cardiovascular disease in type 2 diabetes mellitus (protocol stage)

Active cycle of breathing technique for cystic fibrosis (protocol stage)

Active versus expectant management for women in the third stage of labour (protocol stage)

Acupressure for motion sickness (protocol stage)

Acupuncture for acute management and rehabilitation of traumatic brain injury (protocol stage)

Acupuncture for attention-deficit hyperactivity disorder (ADHD) in children and adolescents (protocol stage)

Acupuncture for autistic spectrum disorder (protocol stage)

Acupuncture for benign prostatic hyperplasia (protocol stage)

Acupuncture for bladder dysfunction after spinal cord injury (protocol stage)

Acupuncture for cancer pain in adults (protocol stage)

Acupuncture for children with cerebral palsy (protocol stage)

Acupuncture for chronic constipation (protocol stage)

Acupuncture for chronic fatigue syndrome (protocol stage)

Acupuncture for chronic hepatitis B virus infection (protocol stage)

Acupuncture for Gilles de la Tourette's syndrome (protocol stage)

Acupuncture for Guillain-Barré syndrome (protocol stage)

Acupuncture for hypoxic ischemic encephalopathy in neonates (protocol stage)

Acupuncture for menopausal hot flushes (protocol stage)

Acupuncture for myopia in children and adolescents (protocol stage)

Acupuncture for pain in endometriosis (protocol stage)

Acupuncture for Parkinson's Disease (protocol stage)

Acupuncture for peripheral joint osteoarthritis (protocol stage)

Acupuncture for polycystic ovarian syndrome (protocol stage)

Acupuncture for postherpetic neuralgia (protocol stage)

Acupuncture for premenstrual syndrome (protocol stage)

Acupuncture for primary dysmenorrhoea (protocol stage)

Acupuncture for symptomatic treatment of diabetic peripheral neuropathy (protocol stage)

Acupuncture for the treatment of post-operative pain (protocol stage)

Acupuncture for tinnitus (protocol stage)

Acupuncture for treating fibromyalgia (protocol stage)

Acupuncture for treatment of erectile dysfunction (protocol stage)

Acupuncture for urinary incontinence in adults without neurological disease (protocol stage)

Acupuncture for uterine fibroids (protocol stage)

Adefovir dipivoxil for chronic hepatitis B (protocol stage)

Adenoidectomy for recurrent or chronic nasal symptoms and middle ear disease in children up to 18 years of age (protocol stage)

Adenosin-diphosphate (ADP) receptor antagonists (clopidogrel, ticlopidine) for the prevention of cardiovascular disease in type 2 diabetes mellitus (protocol stage)

Adherence compounds in embryo transfer media for assisted reproductive technologies (protocol stage)

Adjunctive antithyroid drugs in radioiodine therapy for hyperthyroidism (protocol stage)

Adjunctive hyperbaric oxygen for necrotizing fasciitis (protocol stage)

Adjunctive steroid therapy for managing tuberculosis (protocol stage)

Adjusted indirect comparison for estimating relative effects of competing healthcare interventions (protocol stage)

Adjusting the pH of lidocaine for reducing pain on injection (protocol stage)

Adjuvant chemotherapy and/or radiotherapy after surgery for uterine carcinosarcoma (protocol stage)

Adjuvant chemotherapy for endometrial cancer (protocol stage)

Adjuvant Gonadotropin-releasing hormone analogues for chemotherapy induced premature ovarian failure in premenopausal women (protocol stage)

Adjuvant radiotherapy following radical prostatectomy for prostate cancer (protocol stage)

Adrenaline and vasopressin for cardiac arrest (protocol stage)

Adrenocorticotropic hormone for acute gout (protocol stage)

Advanced glycation end product (AGE) inhibitors for preventing the progression of diabetic kidney disease (protocol stage)

Adverse cardiac effects of calcium channel blockers (protocol stage)

Adverse gastrointestinal effects of COX-2 Inhibitors for inflammatory diseases (protocol stage)

Advice to rest in bed versus advice to stay active for acute low-back pain and sciatica (protocol stage)

Aerosolized prostacyclin for acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) (protocol stage)

Albumin and other plasma expanders for paracentesis treatment of ascites in cirrhotic patients (protocol stage)

Alemtuzumab for chronic lymphocytic leukaemia (protocol stage)

Alendronate for preventing tooth loss in postmenopausal women (protocol stage)

Alfuzosin for benign prostatic hyperplasia (protocol stage)

Allergen injection immunotherapy for perennial allergic rhinitis (protocol stage)

Allogeneic peripheral blood stem cells transplantation versus bone marrow transplantation for the therapy of hematological malignancies (protocol stage)

Allopurinol for chronic gout (protocol stage)

Almitrine-Raubasine combination for dementia (protocol stage)

Alpha-interferon for chronic hepatitis B (protocol stage)

Alpha-lipoic acid for diabetic peripheral neuropathy (protocol stage)

Alprazolam for depression (protocol stage)

Alterations in parenteral nutrition management for the treatment of parenteral nutrition-associated cholestasis in term and preterm infants (protocol stage)

Altered auditory feedback treatments for stuttering in childhood and adolescence (protocol stage)

Altered dietary salt intake for preventing and treating diabetic kidney disease (protocol stage)

Alternative magnesium sulphate regimens for women with pre-eclampsia and eclampsia (protocol stage)

Alternative methods of adenoidectomy versus curettage in children (protocol stage)

Alternative positions for the baby at birth before clamping the umbilical cord (protocol stage)

Alternative strategies for diagnosing gestational diabetes mellitus to improve maternal and infant health (protocol stage)

Alternative strategies for drainage of peritonsillar abscess (protocol stage)

Amfetamines for attention deficit / hyperactivity disorder in adults (protocol stage)

Amide local anaesthetics for post-operative pain relief following third molar surgery (protocol stage)

Amino acid, fat emulsion and energy supplementation for severe pneumonia in the elderly (protocol stage)

Aminobisphosphonates versus other active treatment for Paget's disease of the bone in adults (protocol stage)

Aminoglycosides and other nonsense suppression therapies for the treatment of dystrophinopathy (protocol stage)

Aminophylline for bradyasystolic cardiac arrest in adults (protocol stage)

Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death (protocol stage)

Amisulpride versus other atypical antipsychotics for schizophrenia (protocol stage)

Amphotericin B deoxycholate versus liposomal amphotericin B: effects on kidney function (protocol stage)

Anaesthesia for cardioversion (protocol stage)

Anaesthetic interventions for prevention of awareness during surgery (protocol stage)

Anaesthetic techniques for open inguinal hernia repair in adults (protocol stage)

Analgesia for relief of pain due to uterine cramping/involution after birth. (protocol stage)

Analgesics for postoperative pain after tonsillectomy and adenoidectomy in children (protocol stage)

Analgo-sedation for diagnostic and therapeutic endoscopic or radiologic procedures in adults (protocol stage)

Androgens for the anaemia of chronic kidney disease in adults (protocol stage)

Angiogenesis-inhibitors for metastatic thyroid cancer (protocol stage)

Angiogenesis-inhibitors for the treatment of ovarian cancer (protocol stage)

Angiotensin converting enzyme inhibitor induced angioedema in patients with primary hypertension (protocol stage)

Angiotensin converting enzyme inhibitors and angiotensin II receptor blockers for dialysis patients (protocol stage)

Angiotensin converting enzyme inhibitors and angiotensin receptor blockers for adults with early (stage 1-3) non-diabetic chronic kidney disease (protocol stage)

Angiotensin converting enzyme inhibitors for heart failure (protocol stage)

Angiotensin receptor blockers for heart failure (protocol stage)

Antacids and lifestyle advice for reflux oesophagitis and Endoscopy Negative Reflux Disease (protocol stage)

Antenatal breastfeeding education for increasing breastfeeding duration (protocol stage)

Antenatal cardiotocography for fetal assessment (protocol stage)

Antenatal screening for Down's syndrome - generic protocol (protocol stage)

Anterior repositioning splint for temporomandibular joint disc displacement (protocol stage)

Anthelmintics for people with neurocysticercosis (protocol stage)

Anti Spastic Medication for Spasticity in Cerebral Palsy (protocol stage)

Anti-angiogenic therapy for lung cancer (protocol stage)

Anti-depressants and centrally active agents for fibromyalgia syndrome (protocol stage)

Anti-IL-12/23p40 antibodies for induction of remission in Crohn's disease (protocol stage)

Anti-inflammatory agents for preventing the progression of cervical intraepithelial neoplasia (protocol stage)

Anti-inflammatory medications for obstructive sleep apnea in children (protocol stage)

Anti-pseudomonal beta-lactam monotherapy for the initial, empirical, treatment of febrile neutropenia: comparison of beta-lactams (protocol stage)

Anti-TNF-α treatment for pelvic pain associated with endometriosis (protocol stage)

Anti-vascular endothelial growth factor for macular edema secondary to central retinal vein occlusion (protocol stage)

Anti-vascular endothelial growth factor for neovascular glaucoma (protocol stage)

Antiandrogenic treatment for sexual disinhibition in male patients with dementia (protocol stage)

Antibiotic prophylaxis for elective hysterectomy (protocol stage)

Antibiotic prophylaxis for medical and surgical first-trimester induced abortion (protocol stage)

Antibiotic prophylaxis for patients undergoing elective endoscopic retrograde cholangiopancreatography (protocol stage)

Antibiotic prophylaxis for patients undergoing elective laparoscopic cholecystectomy (protocol stage)

Antibiotic prophylaxis for transrectal prostate biopsy (protocol stage)

Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section (protocol stage)

Antibiotic regimens for the empirical treatment of newborn infants with necrotizing enterocolitis (protocol stage)

Antibiotic regimes and dosages for appendectomy (protocol stage)

Antibiotics and antivirals for dementia and mild cognitive impairment (protocol stage)

Antibiotics for asymptomatic urinary tract infection in the elderly (protocol stage)

Antibiotics for cholangitis and/or cholecystitis (protocol stage)

Antibiotics for clinically diagnosed acute rhinosinusitis in adults (protocol stage)

Antibiotics for hepatic encephalopathy (protocol stage)

Antibiotics for induction of remission in Crohn's disease (protocol stage)

Antibiotics for induction of remission in ulcerative colitis (protocol stage)

Antibiotics for meconium-stained amniotic fluid in labour for preventing neonatal sepsis (protocol stage)

Antibiotics for neonates born through meconium stained amniotic fluid (protocol stage)

Antibiotics for preventing hypertensive diseases in pregnancy (protocol stage)

Antibiotics for preventing urinary tract infections in kidney transplant recipients (protocol stage)

Antibiotics for reactive arthritis (protocol stage)

Antibiotics for secondary prevention of coronary heart disease (protocol stage)

Antibiotics for Staphylococcus aureus pneumonia in adults (protocol stage)

Antibiotics for the management of constipation predominant irritable bowel syndrome and chronic constipation (protocol stage)

Antibiotics for treating human brucellosis (protocol stage)

Antibiotics for treating non typhoidal Salmonella diarrhoea (protocol stage)

Antibiotics for treating postoperative endophthalmitis after cataract surgery (protocol stage)

Antibiotics for treating uncomplicated urinary tract infection in children (protocol stage)

Antibiotics for undifferentiated acute respiratory tract infections in children under five years of age (protocol stage)

Antibiotics for ventilator-associated pneumonia (protocol stage)

Antibiotics plus colony stimulating factors (CSFs) versus CSFs alone and antibiotics plus CSFs versus no prophylaxis for the prevention of infections in cancer patients receiving myelosuppressive chemotherapy or haematopoetic stem cell transplantation (protocol stage)

Antibiotics plus colony stimulating factors versus antibiotics alone for the prevention of infections in cancer patients receiving myelosuppressive chemotherapy or haematopoetic stem cell transplantation (protocol stage)

Antibiotics to prevent complications following tooth extractions (protocol stage)

Antibody immunosuppression for pancreas and kidney/pancreas transplant recipients (protocol stage)

Anticholinergic therapy for acute asthma in children (protocol stage)

Anticholinesterase treatment for myasthenia gravis (protocol stage)

Anticoagulant therapy for deep vein thrombosis (DVT) in pregnancy (protocol stage)

Anticoagulants (extended duration) for prevention of venous thromboembolism following total hip or knee replacement or hip fracture repair (protocol stage)

Anticonvulsants for restless legs syndrome (protocol stage)

Anticonvulsants for tinnitus (protocol stage)

Antidepressants for central pain (protocol stage)

Antidepressants for depression in physically ill people (protocol stage)

Antidepressants for the treatment of abdominal pain-related functional gastrointestinal disorders in children and adolescents (protocol stage)

Antiemetic medication for prevention and treatment of chemotherapy induced nausea and vomiting in childhood (protocol stage)

Antiepileptic drugs as prophylaxis for postcraniotomy seizures (protocol stage)

Antiepileptic drugs for the primary and secondary prevention of seizures after stroke (protocol stage)

Antiepileptic drugs versus no treatment or placebo for children with benign epilepsy with centro temporal spikes (protocol stage)

Antiepileptics for aggression and associated impulsivity (protocol stage)

Antifungal agents for the treatment of mucocutaneous candidiasis in neonates and children (protocol stage)

Antifungal therapy in infants and children with proven, probable or suspected invasive fungal infections (protocol stage)

Antigen-specific active immunotherapy for ovarian cancer (protocol stage)

Antiglucocorticoid and related treatments for psychosis (protocol stage)

Antihistamines as an adjunct to topical nasal steroids for intermittent and persistent allergic rhinitis in children (protocol stage)

Antihistamines for motion sickness (protocol stage)

Antihypertensive agents for preventing the progression of diabetic kidney disease (protocol stage)

Antihypertensive drugs for mild hypertension (protocol stage)

Antimicrobial agents for treating uncomplicated urinary tract infection in women (protocol stage)

Antioxidant micronutrients for lung disease in cystic fibrosis (protocol stage)

Antioxidant supplements for liver diseases (protocol stage)

Antioxidant vitamin supplementation for preventing and slowing the progression of age-related cataract (protocol stage)

Antioxidants for chronic kidney disease (protocol stage)

Antioxidants for female subfertility (protocol stage)

Antioxidants for male subfertility (protocol stage)

Antiplatelet agents for intermittent claudication (protocol stage)

Antipsychotic drugs for anorexia nervosa (protocol stage)

Antipsychotic medication for early episode schizophrenia (protocol stage)

Antipsychotic switching for people with schizophrenia who have neuroleptic-induced weight or metabolic problems (protocol stage)

Antiretroviral resistance testing in treatment-naive HIV-infected adults (protocol stage)

Antiretroviral therapy for infants with HIV infection (protocol stage)

Antithrombotic therapy for improving maternal or infant health outcomes in women considered at risk of placental dysfunction (protocol stage)

Antiviral agents for prophylaxis of herpesviridae infections in patients with haematological malignancies (protocol stage)

Antiviral agents for treating CMV infection of the nervous system in people with HIV (protocol stage)

Antiviral prophylactic intervention for hepatitis C virus in patients undergoing liver transplantation (protocol stage)

Antiviral prophylaxis for varicella zoster in immunocompromised patients (excluding haematological malignancies) (protocol stage)

Antiviral therapy for symptomatic congenital cytomegalovirus infection in neonates and infants up to 3 months of age (protocol stage)

Antiviral treatment for chronic hepatitis C in patients with human immunodeficiency virus (protocol stage)

Antiviral treatments for lamivudine-resistant chronic hepatitis B adult patients (protocol stage)

Antivirals for idiopathic sudden sensorineural hearing loss (protocol stage)

Appendix stump closure during laparoscopic appendectomy (protocol stage)

Aquatic therapy exercise for treating rheumatoid arthritis (protocol stage)

Aripiprazole alone or in combination for acute mania (protocol stage)

Aripiprazole for psychosis-induced aggression or agitation (protocol stage)

Aripiprazole versus placebo for schizophrenia (protocol stage)

Aromatase inhibitors for ovulation induction (protocol stage)

Aromatherapy for treatment of postoperative nausea and vomiting (protocol stage)

Arterial ligation versus embolisation for intractable posterior epistaxis (protocol stage)

Arthroscopic lavage for osteoarthritis of the knee (protocol stage)

Arthroscopy for temporomandibular disorders (protocol stage)

As required versus fixed schedule analgesic administration schedules for treating postoperative pain in children and adults (protocol stage)

Aspirin desensitisation therapy for aspirin-intolerant chronic rhinosinusitis (protocol stage)

Aspirin for primary prevention of coronary heart disease (protocol stage)

Aspirin with or without an antiemetic for acute migraine in adults (protocol stage)

Aspirin, steroidal and non-steroidal anti-inflammatory drugs for Alzheimer's disease (protocol stage)

Atherectomy for peripheral arterial disease (protocol stage)

Atomoxetine for attention deficit hyperactivity disorder in people with intellectual disabilities (protocol stage)

Atraumatic restorative treatment versus conventional restorative treatment for the management of dental caries (protocol stage)

Atypical Antipsychotics for Tourette's Syndrome (protocol stage)

Augmentation of psychotherapy with d-cycloserine for anxiety disorders (protocol stage)

Auricular acupuncture for opiate dependence in substance misuse treatment programmes (protocol stage)

Autologous platelet rich-plasma for treating chronic wounds (protocol stage)

Autologous stem cell transplantation vs chemotherapy in adult acute lymphocytic leukaemia (protocol stage)

Autologous versus prosthetic arteriovenous fistulae for vascular access (protocol stage)

Axillary staging for operable primary breast cancer. (protocol stage)

Azithromycin for treating uncomplicated malaria (protocol stage)

Azithromycin versus penicillin G Benzathine for early syphilis (protocol stage)

Azoles and ivermectin for treating strongyloides infection (protocol stage)

Bacille Calmette-Guerin (BCG) vaccine for induction of remission in Crohn's disease (protocol stage)

Balance training (proprioceptive training) for patients with rheumatoid arthritis. (protocol stage)

Band ligation versus beta-blockers for primary prevention of bleeding oesophageal varices (protocol stage)

Banding ligation versus beta-blockers for primary prophylaxis in oesophageal varices (protocol stage)

Banked preterm versus banked term human milk to promote growth and development in very low birth weight infants (protocol stage)

Bariatric surgery for non-alcoholic steatohepatitis in obese patients (protocol stage)

Behavioral interventions for increasing the use of condoms in women with HIV (protocol stage)

Behavioral interventions for reducing HIV infection in employees in occupational settings (protocol stage)

Behavioral interventions to reduce the transmission of HIV infection among commercial sex workers and their clients in developed countries (protocol stage)

Behavioral interventions to reduce the transmission of HIV infection among commercial sex workers and their clients in developing countries (protocol stage)

Behavioral therapies for migraine (protocol stage)

Behavioural interventions for children under five years with sleep difficulties (protocol stage)

Benzodiazepines for restless legs syndrome (protocol stage)

Benzodiazepines for the relief of breathlessness in advanced malignant and non-malignant diseases in adults (protocol stage)

Beta blockers for essential tremor (protocol stage)

Beta blockers for preventing stroke recurrence (protocol stage)

Beta blockers for stable angina (protocol stage)

Beta-2 agonists for exercise induced asthma (protocol stage)

Beta-adrenergic blockers for perioperative cardiac risk reduction in patients undergoing vascular surgery (protocol stage)

Beta-blocker plus nitrates for secondary prevention of variceal bleeding (protocol stage)

Beta-blockers alone or with endoscopic therapy for prevention of variceal rebleeding in portal hypertension (protocol stage)

Beta-blockers for heart failure (protocol stage)

Beta-blockers for mitral stenosis (protocol stage)

Beta-blockers for myocardial infarction (protocol stage)

Beta-blockers for unstable angina (protocol stage)

Bibliotherapy for sexual dysfunction (protocol stage)

Bicarbonate versus lactate solutions for acute haemodialysis (protocol stage)

Bicarbonate versus lactate solutions for acute peritoneal dialysis (protocol stage)

Bilateral versus single internal mammary artery bypass grafts for coronary arterial atherosclerosis (protocol stage)

Biocompatible dialysis fluids for peritoneal dialysis (protocol stage)

Biodegradable anastomotic ring for gastrointestinal anastomosis (protocol stage)

Biofeedback for pain during labour (protocol stage)

Biologics for chronic plaque psoriasis (protocol stage)

Biphasic versus monophasic waveforms for transthoracic defibrillation in out-of-hospital cardiac arrest (protocol stage)

Bisphosphonates for prevention of bone loss in women with early breast cancer (protocol stage)

Bisphosphonates in early prostate cancer (protocol stage)

Black cohosh (Cimicifuga spp.) for menopausal symptoms (protocol stage)

Blinded versus unblinded assessments of risk-of-bias in studies included in a systematic review (protocol stage)

Blood pressure control for diabetic retinopathy (protocol stage)

Blood pressure increasing effect of sibutramine in obese patients (protocol stage)

Blood pressure lowering efficacy of beta-1 selective beta blockers for primary hypertension (protocol stage)

Blood pressure lowering efficacy of beta-blockers as second-line therapy for primary hypertension (protocol stage)

Blood pressure lowering efficacy of calcium channel blockers for primary hypertension (protocol stage)

Blood pressure lowering efficacy of calcium-channel blockers as second-line therapy for primary hypertension (protocol stage)

Blood pressure lowering efficacy of drugs inhibiting the renin-angiotensin system as second-line therapy for primary hypertension (protocol stage)

Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension (protocol stage)

Blood pressure lowering efficacy of non-selective beta blockers for primary hypertension (protocol stage)

Blood pressure lowering efficacy of partial agonist beta blockers for primary hypertension (protocol stage)

Blood pressure lowering efficacy of potassium-sparing diuretics (that block the epithelial sodium channel) for primary hypertension (protocol stage)

Blood pressure lowering efficacy of thiazide diuretics for primary hypertension (protocol stage)

Blood substitutes for avoiding allogeneic blood transfusion (protocol stage)

Blood transfusions for treating acute chest syndrome in people with sickle cell disease (protocol stage)

Blood-pressure-lowering treatment for preventing recurrent stroke, major vascular events, and dementia in patients with a history of stroke or transient ischaemic attacks (protocol stage)

Body position for spontaneously breathing preterm infants with apnoea (protocol stage)

Bone morphogenetic protein (BMP) for fracture healing in adults (protocol stage)

Boosted protease inhibitor (PI) monotherapy for treating HIV/AIDS (protocol stage)

Botulinum A toxin for focal hand dystonia (protocol stage)

Botulinum toxin A for the prevention of hip dislocation in cerebral palsy (protocol stage)

Botulinum toxin for adult spasticity after stroke or non-progressive brain lesion (protocol stage)

Botulinum toxin for myofascial pain syndromes in adults (protocol stage)

Botulinum toxin for the treatment of chronic idiopathic constipation (protocol stage)

Botulinum toxin type A and casting versus botulinum toxin type A or casting in treating equinus gait of children with cerebral palsy (protocol stage)

Botulinum toxin type A formulations in focal dystonias (protocol stage)

Bowel preparation for colonoscopy (protocol stage)

Braces for idiopathic scoliosis in adolescents (protocol stage)

Buprenorphine for cancer pain (protocol stage)

Bupropion for depression (protocol stage)

Caffeine for cognition (protocol stage)

Calcineurin inhibitor withdrawal or tapering for kidney transplant recipients (protocol stage)

Calcium antagonists for unstable angina (protocol stage)

Calcium channel blockers for primary Raynaud's Phenomenon (protocol stage)

Calcium channel blockers for Raynaud's phenomenon in patients with scleroderma (protocol stage)

Calcium channel blockers for treatment of irritable bowel syndrome (protocol stage)

Calcium channel blockers for ureteral stones (protocol stage)

Calcium channel blockers versus other classes of drugs for hypertension (protocol stage)

Calcium dialysate concentration for peritoneal dialysis (protocol stage)

Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes (protocol stage)

Cannabinoids for multiple sclerosis (protocol stage)

Carbamazepine and oxcarbazepine for the treatment of behavioural and psychological symptoms of dementia (BPSD) (protocol stage)

Carbohydrates for improving the cognitive performance of independent-living older adults with normal cognition or mild cognitive impairment (protocol stage)

Cardiotocography versus intermittent auscultation of fetal heart on admission to labour ward for assessment of fetal wellbeing (protocol stage)

Care delivery and self-management strategies for children with epilepsy (protocol stage)

Carnitine for fatigue in multiple sclerosis (protocol stage)

Case management: effects on professional practice and health care outcomes (protocol stage)

Catheter ablation for paroxysmal and persistent atrial fibrillation (protocol stage)

Catheter impregnation, coating or bonding for reducing central venous catheter related infections in adults (protocol stage)

Cefepime versus other beta-lactam antibiotics for the treatment of infections in non-neutropenic patients (protocol stage)

Celiac plexus block for pancreatic cancer pain in adults (protocol stage)

Cemented versus cementless in total knee arthroplasty for osteoarthrosis and other non-traumatic diseases (protocol stage)

Cemented versus cementless surgical approach for total hip arthroplasty revision (protocol stage)

Cemented versus cementless total hip arthroplasty for osteoarthrosis and other non-traumatic diseases (protocol stage)

Centralisation of services for gynaecological cancer (protocol stage)

Cerebrolysin for acute Ischaemic stroke (protocol stage)

Cerebrolysin for Alzheimer's disease (protocol stage)

Certolizumab pegol (CDP870) for rheumatoid arthritis in adults (protocol stage)

Cervical pessary for preventing preterm birth (protocol stage)

Cervical preparation for first trimester surgical abortion (protocol stage)

Cervical preparation for second trimester dilation and evacuation (protocol stage)

Cesarean section for the prevention of anal incontinence (protocol stage)

Changes in out-of-pocket payments on utilisation of health care services (protocol stage)

Checking reference lists to find additional studies for systematic reviews (protocol stage)

Chemo-mechanical treatment of tooth decay (protocol stage)

Chemotherapy alone versus chemotherapy plus radiotherapy for early stage Hodgkin Lymphoma (protocol stage)

Chemotherapy alone vs. radiotherapy alone vs. chemotherapy plus radiotherapy in the primary treatment of localised non-Hodgkin's lymphoma (protocol stage)

Chemotherapy and supportive care versus supportive care alone in advanced non-small cell lung cancer (protocol stage)

Chemotherapy and/or radiotherapy after surgery for ovarian carcinosarcoma (protocol stage)

Chemotherapy for brain metastases from small cell lung cancer (protocol stage)

Chemotherapy for children with medulloblastoma (protocol stage)

Chemotherapy for gallbladder cancer (protocol stage)

Chemotherapy for malignant germ cell ovarian cancer in patients with early stage, advanced and recurrent disease (protocol stage)

Chemotherapy for metastatic and recurrent cervical cancer (protocol stage)

Chemotherapy of second-stage Human African trypanosomiasis (protocol stage)

Chemotherapy with Camptothecin compounds for metastatic colorectal cancer (protocol stage)

Chemotherapy with platinum compounds for metastatic colorectal cancer (protocol stage)

Chemotherapy, surgery and radiotherapy for locally advanced breast cancer (protocol stage)

Chest pain observation units for patients with symptoms suggestive of acute cardiac ischaemia (protocol stage)

Chest physiotherapy for pneumonia in adults (protocol stage)

Chewing gum for postoperative ileus (protocol stage)

Child-focused cognitive behavioural therapy for children who have been physically abused (protocol stage)

Chinese herbal medicine for allergic rhinitis (protocol stage)

Chinese herbal medicine for diabetic peripheral neuropathy (protocol stage)

Chinese herbal medicine for female subfertility (protocol stage)

Chinese herbal medicine for subfertile women with polycystic ovarian syndrome (protocol stage)

Chinese herbal medicines alone or combined with vitamins for the treatment of gastric precancerous lesions (protocol stage)

Chinese herbal medicines for induction of remission in advanced or late gastric cancer (protocol stage)

Chinese herbal medicines for treating diabetic foot ulcers (protocol stage)

Chinese herbal medicines for weight loss (protocol stage)

Chinese herbs for insomnia (protocol stage)

Chinese medicinal herbs for diabetic kidney disease (protocol stage)

Chinese medicinal herbs for urinary calculi (protocol stage)

Chinese medicinal herbs for vaginal bleeding of medical abortion (protocol stage)

Chiropractic for infantile colic (protocol stage)

Chiropractic interventions (other than trials of spinal manipulation alone) for low-back pain (protocol stage)

Chlamydia antibody titer testing versus hysterosalpingography for detection of tubal pathology in subfertile women (protocol stage)

Chlorhexidine interventions for the prevention of caries in adults (protocol stage)

Chlorhexidine skin care for the prevention of infection in term neonates (protocol stage)

Chloroquines for the treatment of osteoarthritis (protocol stage)

Chlorpromazine for psychosis induced aggression or agitation (protocol stage)

Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease (protocol stage)

Chondroitin for osteoarthritis (protocol stage)

Chronic disease management programs for adults with asthma (protocol stage)

Chronotherapy versus conventional drug therapy for hypertension (protocol stage)

Chuanxiong preparations for preventing stroke (protocol stage)

Cilostazol versus aspirin for secondary prevention of vascular events after stroke (protocol stage)

Cinnamon for diabetes mellitus (protocol stage)

Circuit class therapy for improving mobility after stroke (protocol stage)

Cisapride for intestinal constipation (protocol stage)

Cisplatin plus etoposide versus other platin-based regimens for patients with extensive small cell lung cancer (protocol stage)

Citalopram versus other anti-depressive agents for depression (protocol stage)

Clinical assessment for diagnosing congenital heart disease in newborn infants with Down syndrome (protocol stage)

Clinical hypnosis for acute pain in adults (protocol stage)

Clinical pathways: effects on professional practice, patient outcomes, length of stay and hospital costs (protocol stage)

Clinically indicated replacement versus routine replacement of peripheral venous catheters (protocol stage)

Clobazam monotherapy for partial onset or generalized onset seizures (protocol stage)

Closure methods for laparotomy incisions (protocol stage)

Clozapine versus other atypical antipsychotics for schizophrenia (protocol stage)

Codeine, alone and with paracetamol (acetaminophen), for cancer pain (protocol stage)

Coenzyme Q10 for Parkinson's disease (protocol stage)

Cognition-based interventions for healthy older people and people with mild cognitive impairment (protocol stage)

Cognitive behaviour therapy versus specific pharmacological treatments for schizophrenia (protocol stage)

Cognitive behaviour therapy versus standard care for schizophrenia (protocol stage)

Cognitive Behavioural Therapy (CBT) for adults with HIV (protocol stage)

Cognitive behavioural therapy for anxiety disorders in later life (protocol stage)

Cognitive behavioural therapy for insomnia (protocol stage)

Cognitive behavourial therapy for patients with implantable cardioverter-defibrillators (protocol stage)

Cognitive reframing for carers of people with dementia (protocol stage)

Cognitive rehabilitation for occupational outcomes after traumatic brain injury (protocol stage)

Cognitive stimulation to improve cognitive functioning in people with dementia (protocol stage)

Cognitive-behavioural therapy for parents who have physically abused their children (protocol stage)

Collaboration between local health and local government agencies for health improvement (protocol stage)

Collaborative care for depression and anxiety problems in primary care (protocol stage)

Colloid versus crystalloid solutions for priming cardiopulmonary bypass circuits (protocol stage)

Colonoscopic polypectomy for prevention of colorectal cancer (protocol stage)

Colony stimulating factors for afebrile neutropenia in cancer patients (protocol stage)

Colony-stimulating factors for the prevention of chemotherapy induced febrile neutropenia in breast cancer patients (protocol stage)

Colorectal stents for the management of malignant colonic obstructions (protocol stage)

Combination inhaled steroid and long-acting beta-agonist versus tiotropium for chronic obstructive pulmonary disease (protocol stage)

Combination of tocolytic agents for inhibiting preterm labour (protocol stage)

Combinations of insulin and oral hypoglycaemic agents for people with type 2 diabetes mellitus on insulin treatment (protocol stage)

Combined inhaled beta-agonist and anticholinergic agents in the emergency management of adult asthmatic patients (protocol stage)

Combined pharmacotherapy and psychological therapies for post traumatic stress disorder (PTSD) (protocol stage)

Combined spinal-epidural versus spinal anaesthesia for caesarean section (protocol stage)

Combined therapy with statins and fibrates for people with dyslipidaemia (protocol stage)

Combined use of hyperthermia and radiation therapy for treating locally advanced cervical carcinoma (protocol stage)

Community based management of neonatal sepsis in developing countries (protocol stage)

Community clinics versus home management for leg ulcer treatment (protocol stage)

Community-based intervention package for preventing maternal morbidity and mortality and improving neonatal outcomes (protocol stage)

Comparing antibiotics for acute exacerbations of chronic obstructive pulmonary disease (protocol stage)

Comparison of chemotherapy including escalated BEACOPP versus chemotherapy including ABVD for patients with early unfavourable or advanced stage Hodgkin lymphoma (protocol stage)

Comparison of different regimens of proton pump inhibitors for acute peptic ulcer bleeding (protocol stage)

Comparison of intraocular lens types for cataract surgery in eyes with uveitis (protocol stage)

Comparison of medicinal herbs for chronic hepatitis B virus infection (protocol stage)

Complementary therapies for acne vulgaris (protocol stage)

Complete decongestive therapy for lymphedema following breast cancer treatment (protocol stage)

Complex interventions for preventing diabetic foot ulceration (protocol stage)

Comprehensive geriatric assessment for older adults admitted to hospital (protocol stage)

Comprehensive physiotherapy for rheumatoid arthritis (protocol stage)

Computer assisted knee arthroplasty for osteoarthritis and other non-traumatic diseases (protocol stage)

Computer assisted surgery for knee ligament reconstruction (protocol stage)

Computer-based interventions for weight loss or weight maintenance in overweight or obese people (protocol stage)

Computer-generated paper reminders: effects on professional practice and health care outcomes (protocol stage)

Conscious sedation for dental anxiety (protocol stage)

Conservative interventions for the management of foreign body impaction in the oesophagus (protocol stage)

Conservative management of nocturia in adults (protocol stage)

Consultation letters for medically unexplained physical symptoms (protocol stage)

Consultation liaison in primary practice for mental health problems (protocol stage)

Consumer-oriented interventions for evidence-based prescribing and medicine use: an overview of systematic reviews (protocol stage)

Continuation and maintenance treatments for depressive disorder in older adults (protocol stage)

Continuous glucose monitoring systems for type 1 diabetes mellitus (protocol stage)

Continuous interscalene blockade versus parenteral analgesia for postoperative pain relief after major shoulder surgery (protocol stage)

Continuous positive airway pressure for cardiovascular disease associated with sleep apneoa (protocol stage)

Continuous quality improvement: effects on professional practice and healthcare outcomes (protocol stage)

Continuous renal replacement modalities for acute kidney failure in critically ill patients (protocol stage)

Continuous subcutaneous insulin infusion (CSII) versus multiple insulin injections for type 1 diabetes mellitus (protocol stage)

Contrast agents for preventing contrast-induced nephropathy (protocol stage)

Control interventions for preventing spread of vancomycin-resistant enterococci (VRE) in hospitals (protocol stage)

Controlled cord traction for the third stage of labour (protocol stage)

Cooling for cerebral protection during brain surgery (protocol stage)

Copper containing intra-uterine devices versus depot progestogens for contraception (protocol stage)

Corticosteroid injections for tennis elbow (protocol stage)

Corticosteroid regimens for treatment of acute and chronic graft versus host disease (GvHD) after allogenic stem cell transplantation (protocol stage)

Corticosteroids for HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome in pregnancy (protocol stage)

Corticosteroids for ocular toxoplasmosis (protocol stage)

Corticosteroids for pneumonia (protocol stage)

Corticosteroids for the common cold (protocol stage)

Covering ileo- or colostomy in anterior resection for rectal carcinoma (protocol stage)

Cox-2 Inhibitors in the Prevention of Melanoma (protocol stage)

Creatine for amyotrophic lateral sclerosis/motor neuron disease (protocol stage)

Cryoablation versus radiofrequency ablation for the treatment of small renal cell carcinoma (protocol stage)

Cryotherapy following total knee replacement (protocol stage)

Culture media for human preimplantation embryos for in assisted reproductive technology cycles (protocol stage)

Cultured epithelial autograft in the treatment of acute burn wounds (protocol stage)

Cyanoacrylate microbial sealants for skin preparation prior to surgery (protocol stage)

Cycled light in the intensive care unit for preterm/low birth weight infants (protocol stage)

Cyclo-oxygenase (COX) inhibitors for preventing preterm labour (protocol stage)

Cyclophosphamide for interstitial lung disease (protocol stage)

Cyclophosphamide versus ifosfamide for paediatric and young adult sarcoma patients (protocol stage)

Cyclosporine for maintenance of remission in Crohn's disease (protocol stage)

Cytosine arabinoside for the treatment of acute promyelocytic leukaemia (protocol stage)

Daclizumab for relapsing remitting multiple sclerosis (protocol stage)

Damage control surgery for abdominal trauma (protocol stage)

Dance movement therapy for improving psychological and physical outcomes in cancer patients (protocol stage)

De-escalation of antimicrobial treatment for adults with sepsis, severe sepsis or septic shock (protocol stage)

Debriefing for the prevention of psychological trauma in women following childbirth (protocol stage)

Decongestants, antihistamines and nasal irrigation for acute sinusitis in children (protocol stage)

Deep brain stimulation of subthalamic nucleus for Parkinson's disease (protocol stage)

Deferasirox for managing iron overload in patients with myelodysplastic syndrome (protocol stage)

Deferasirox for managing iron overload in people with thalassaemia (protocol stage)

Deferasirox for managing transfusional iron overload in people with sickle cell disease (protocol stage)

Dehydroepiandrosterone for postmenopausal women (protocol stage)

Deliberate hypotension with propofol under anaesthesia for functional endoscopic sinus surgery (FESS) (protocol stage)

Dietary interventions for preventing complications in idiopathic hypercalciuria (protocol stage)

Dietary probiotic supplementation for allergic rhinitis (protocol stage)

Dietary supplements for established atopic eczema (protocol stage)

Different antibiotic regimens for treating asymptomatic bacteriuria in pregnancy (protocol stage)

Different antibiotic treatments for group A streptococcal pharyngitis (protocol stage)

Different communication strategies for disclosing results of diagnostic prenatal testing (protocol stage)

Different durations of corticosteroid therapy for exacerbations of chronic obstructive pulmonary disease (protocol stage)

Different insulin regimens for type 2 diabetes mellitus (protocol stage)

Different methods for the induction of labour in outpatient settings (protocol stage)

Different techniques of blood glucose monitoring in women with gestational diabetes for improving maternal and infant health (protocol stage)

Dilute versus full strength formula in preterm or very low birth weight infants (protocol stage)

Direct composite resin fillings versus amalgam fillings for permanent or adult posterior teeth (protocol stage)

Direct thrombin inhibitors versus vitamin K antagonists or low molecular weight heparins for prevention of venous thromboembolism following total hip or knee replacement (protocol stage)

Disulfiram for the treatment of cocaine dependence (protocol stage)

Disulphiram for alcohol dependence (protocol stage)