Absorbable versus non-absorbable sutures for primary closure of traumatic lacerations and surgical wounds (protocol stage)

Acamprosate for alcohol dependence (protocol stage)

Acetylcholinesterase inhibitors for schizophrenia (protocol stage)

Acetylsalicylic acid (Aspirin) for primary prevention of cardiovascular disease in type 2 diabetes mellitus (protocol stage)

Active cycle of breathing technique for cystic fibrosis (protocol stage)

Active versus expectant management for women in the third stage of labour (protocol stage)

Acupressure for motion sickness (protocol stage)

Acupuncture for acute management and rehabilitation of traumatic brain injury (protocol stage)

Acupuncture for attention-deficit hyperactivity disorder (ADHD) in children and adolescents (protocol stage)

Acupuncture for autistic spectrum disorder (protocol stage)

Acupuncture for benign prostatic hyperplasia (protocol stage)

Acupuncture for bladder dysfunction after spinal cord injury (protocol stage)

Acupuncture for cancer pain in adults (protocol stage)

Acupuncture for children with cerebral palsy (protocol stage)

Acupuncture for chronic constipation (protocol stage)

Acupuncture for chronic fatigue syndrome (protocol stage)

Acupuncture for chronic hepatitis B virus infection (protocol stage)

Acupuncture for Gilles de la Tourette's syndrome (protocol stage)

Acupuncture for Guillain-Barré syndrome (protocol stage)

Acupuncture for hypoxic ischemic encephalopathy in neonates (protocol stage)

Acupuncture for menopausal hot flushes (protocol stage)

Acupuncture for myopia in children and adolescents (protocol stage)

Acupuncture for pain in endometriosis (protocol stage)

Acupuncture for Parkinson's Disease (protocol stage)

Acupuncture for peripheral joint osteoarthritis (protocol stage)

Acupuncture for polycystic ovarian syndrome (protocol stage)

Acupuncture for postherpetic neuralgia (protocol stage)

Acupuncture for premenstrual syndrome (protocol stage)

Acupuncture for primary dysmenorrhoea (protocol stage)

Acupuncture for symptomatic treatment of diabetic peripheral neuropathy (protocol stage)

Acupuncture for the treatment of post-operative pain (protocol stage)

Acupuncture for tinnitus (protocol stage)

Acupuncture for treating fibromyalgia (protocol stage)

Acupuncture for treatment of erectile dysfunction (protocol stage)

Acupuncture for urinary incontinence in adults without neurological disease (protocol stage)

Acupuncture for uterine fibroids (protocol stage)

Adefovir dipivoxil for chronic hepatitis B (protocol stage)

Adenoidectomy for recurrent or chronic nasal symptoms and middle ear disease in children up to 18 years of age (protocol stage)

Adenosin-diphosphate (ADP) receptor antagonists (clopidogrel, ticlopidine) for the prevention of cardiovascular disease in type 2 diabetes mellitus (protocol stage)

Adherence compounds in embryo transfer media for assisted reproductive technologies (protocol stage)

Adjunctive antithyroid drugs in radioiodine therapy for hyperthyroidism (protocol stage)

Adjunctive hyperbaric oxygen for necrotizing fasciitis (protocol stage)

Adjunctive steroid therapy for managing tuberculosis (protocol stage)

Adjusted indirect comparison for estimating relative effects of competing healthcare interventions (protocol stage)

Adjusting the pH of lidocaine for reducing pain on injection (protocol stage)

Adjuvant chemotherapy and/or radiotherapy after surgery for uterine carcinosarcoma (protocol stage)

Adjuvant chemotherapy for endometrial cancer (protocol stage)

Adjuvant Gonadotropin-releasing hormone analogues for chemotherapy induced premature ovarian failure in premenopausal women (protocol stage)

Adjuvant radiotherapy following radical prostatectomy for prostate cancer (protocol stage)

Adrenaline and vasopressin for cardiac arrest (protocol stage)

Adrenocorticotropic hormone for acute gout (protocol stage)

Advanced glycation end product (AGE) inhibitors for preventing the progression of diabetic kidney disease (protocol stage)

Adverse cardiac effects of calcium channel blockers (protocol stage)

Adverse gastrointestinal effects of COX-2 Inhibitors for inflammatory diseases (protocol stage)

Advice to rest in bed versus advice to stay active for acute low-back pain and sciatica (protocol stage)

Aerosolized prostacyclin for acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) (protocol stage)

Albumin and other plasma expanders for paracentesis treatment of ascites in cirrhotic patients (protocol stage)

Alemtuzumab for chronic lymphocytic leukaemia (protocol stage)

Alendronate for preventing tooth loss in postmenopausal women (protocol stage)

Alfuzosin for benign prostatic hyperplasia (protocol stage)

Allergen injection immunotherapy for perennial allergic rhinitis (protocol stage)

Allogeneic peripheral blood stem cells transplantation versus bone marrow transplantation for the therapy of hematological malignancies (protocol stage)

Allopurinol for chronic gout (protocol stage)

Almitrine-Raubasine combination for dementia (protocol stage)

Alpha-interferon for chronic hepatitis B (protocol stage)

Alpha-lipoic acid for diabetic peripheral neuropathy (protocol stage)

Alprazolam for depression (protocol stage)

Alterations in parenteral nutrition management for the treatment of parenteral nutrition-associated cholestasis in term and preterm infants (protocol stage)

Altered auditory feedback treatments for stuttering in childhood and adolescence (protocol stage)

Altered dietary salt intake for preventing and treating diabetic kidney disease (protocol stage)

Alternative magnesium sulphate regimens for women with pre-eclampsia and eclampsia (protocol stage)

Alternative methods of adenoidectomy versus curettage in children (protocol stage)

Alternative positions for the baby at birth before clamping the umbilical cord (protocol stage)

Alternative strategies for diagnosing gestational diabetes mellitus to improve maternal and infant health (protocol stage)

Alternative strategies for drainage of peritonsillar abscess (protocol stage)

Amfetamines for attention deficit / hyperactivity disorder in adults (protocol stage)

Amide local anaesthetics for post-operative pain relief following third molar surgery (protocol stage)

Amino acid, fat emulsion and energy supplementation for severe pneumonia in the elderly (protocol stage)

Aminobisphosphonates versus other active treatment for Paget's disease of the bone in adults (protocol stage)

Aminoglycosides and other nonsense suppression therapies for the treatment of dystrophinopathy (protocol stage)

Aminophylline for bradyasystolic cardiac arrest in adults (protocol stage)

Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death (protocol stage)

Amisulpride versus other atypical antipsychotics for schizophrenia (protocol stage)

Amphotericin B deoxycholate versus liposomal amphotericin B: effects on kidney function (protocol stage)

Anaesthesia for cardioversion (protocol stage)

Anaesthetic interventions for prevention of awareness during surgery (protocol stage)

Anaesthetic techniques for open inguinal hernia repair in adults (protocol stage)

Analgesia for relief of pain due to uterine cramping/involution after birth. (protocol stage)

Analgesics for postoperative pain after tonsillectomy and adenoidectomy in children (protocol stage)

Analgo-sedation for diagnostic and therapeutic endoscopic or radiologic procedures in adults (protocol stage)

Androgens for the anaemia of chronic kidney disease in adults (protocol stage)

Angiogenesis-inhibitors for metastatic thyroid cancer (protocol stage)

Angiogenesis-inhibitors for the treatment of ovarian cancer (protocol stage)

Angiotensin converting enzyme inhibitor induced angioedema in patients with primary hypertension (protocol stage)

Angiotensin converting enzyme inhibitors and angiotensin II receptor blockers for dialysis patients (protocol stage)

Angiotensin converting enzyme inhibitors and angiotensin receptor blockers for adults with early (stage 1-3) non-diabetic chronic kidney disease (protocol stage)

Angiotensin converting enzyme inhibitors for heart failure (protocol stage)

Angiotensin receptor blockers for heart failure (protocol stage)

Antacids and lifestyle advice for reflux oesophagitis and Endoscopy Negative Reflux Disease (protocol stage)

Antenatal breastfeeding education for increasing breastfeeding duration (protocol stage)

Antenatal cardiotocography for fetal assessment (protocol stage)

Antenatal screening for Down's syndrome - generic protocol (protocol stage)

Anterior repositioning splint for temporomandibular joint disc displacement (protocol stage)

Anthelmintics for people with neurocysticercosis (protocol stage)

Anti Spastic Medication for Spasticity in Cerebral Palsy (protocol stage)

Anti-angiogenic therapy for lung cancer (protocol stage)

Anti-depressants and centrally active agents for fibromyalgia syndrome (protocol stage)

Anti-IL-12/23p40 antibodies for induction of remission in Crohn's disease (protocol stage)

Anti-inflammatory agents for preventing the progression of cervical intraepithelial neoplasia (protocol stage)

Anti-inflammatory medications for obstructive sleep apnea in children (protocol stage)

Anti-pseudomonal beta-lactam monotherapy for the initial, empirical, treatment of febrile neutropenia: comparison of beta-lactams (protocol stage)

Anti-TNF-α treatment for pelvic pain associated with endometriosis (protocol stage)

Anti-vascular endothelial growth factor for macular edema secondary to central retinal vein occlusion (protocol stage)

Anti-vascular endothelial growth factor for neovascular glaucoma (protocol stage)

Antiandrogenic treatment for sexual disinhibition in male patients with dementia (protocol stage)

Antibiotic prophylaxis for elective hysterectomy (protocol stage)

Antibiotic prophylaxis for medical and surgical first-trimester induced abortion (protocol stage)

Antibiotic prophylaxis for patients undergoing elective endoscopic retrograde cholangiopancreatography (protocol stage)

Antibiotic prophylaxis for patients undergoing elective laparoscopic cholecystectomy (protocol stage)

Antibiotic prophylaxis for transrectal prostate biopsy (protocol stage)

Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section (protocol stage)

Antibiotic regimens for the empirical treatment of newborn infants with necrotizing enterocolitis (protocol stage)

Antibiotic regimes and dosages for appendectomy (protocol stage)

Antibiotics and antivirals for dementia and mild cognitive impairment (protocol stage)

Antibiotics for asymptomatic urinary tract infection in the elderly (protocol stage)

Antibiotics for cholangitis and/or cholecystitis (protocol stage)

Antibiotics for clinically diagnosed acute rhinosinusitis in adults (protocol stage)

Antibiotics for hepatic encephalopathy (protocol stage)

Antibiotics for induction of remission in Crohn's disease (protocol stage)

Antibiotics for induction of remission in ulcerative colitis (protocol stage)

Antibiotics for meconium-stained amniotic fluid in labour for preventing neonatal sepsis (protocol stage)

Antibiotics for neonates born through meconium stained amniotic fluid (protocol stage)

Antibiotics for preventing hypertensive diseases in pregnancy (protocol stage)

Antibiotics for preventing urinary tract infections in kidney transplant recipients (protocol stage)

Antibiotics for reactive arthritis (protocol stage)

Antibiotics for secondary prevention of coronary heart disease (protocol stage)

Antibiotics for Staphylococcus aureus pneumonia in adults (protocol stage)

Antibiotics for the management of constipation predominant irritable bowel syndrome and chronic constipation (protocol stage)

Antibiotics for treating human brucellosis (protocol stage)

Antibiotics for treating non typhoidal Salmonella diarrhoea (protocol stage)

Antibiotics for treating postoperative endophthalmitis after cataract surgery (protocol stage)

Antibiotics for treating uncomplicated urinary tract infection in children (protocol stage)

Antibiotics for undifferentiated acute respiratory tract infections in children under five years of age (protocol stage)

Antibiotics for ventilator-associated pneumonia (protocol stage)

Antibiotics plus colony stimulating factors (CSFs) versus CSFs alone and antibiotics plus CSFs versus no prophylaxis for the prevention of infections in cancer patients receiving myelosuppressive chemotherapy or haematopoetic stem cell transplantation (protocol stage)

Antibiotics plus colony stimulating factors versus antibiotics alone for the prevention of infections in cancer patients receiving myelosuppressive chemotherapy or haematopoetic stem cell transplantation (protocol stage)

Antibiotics to prevent complications following tooth extractions (protocol stage)

Antibody immunosuppression for pancreas and kidney/pancreas transplant recipients (protocol stage)

Anticholinergic therapy for acute asthma in children (protocol stage)

Anticholinesterase treatment for myasthenia gravis (protocol stage)

Anticoagulant therapy for deep vein thrombosis (DVT) in pregnancy (protocol stage)

Anticoagulants (extended duration) for prevention of venous thromboembolism following total hip or knee replacement or hip fracture repair (protocol stage)

Anticonvulsants for restless legs syndrome (protocol stage)

Anticonvulsants for tinnitus (protocol stage)

Antidepressants for central pain (protocol stage)

Antidepressants for depression in physically ill people (protocol stage)

Antidepressants for the treatment of abdominal pain-related functional gastrointestinal disorders in children and adolescents (protocol stage)

Antiemetic medication for prevention and treatment of chemotherapy induced nausea and vomiting in childhood (protocol stage)

Antiepileptic drugs as prophylaxis for postcraniotomy seizures (protocol stage)

Antiepileptic drugs for the primary and secondary prevention of seizures after stroke (protocol stage)

Antiepileptic drugs versus no treatment or placebo for children with benign epilepsy with centro temporal spikes (protocol stage)

Antiepileptics for aggression and associated impulsivity (protocol stage)

Antifungal agents for the treatment of mucocutaneous candidiasis in neonates and children (protocol stage)

Antifungal therapy in infants and children with proven, probable or suspected invasive fungal infections (protocol stage)

Antigen-specific active immunotherapy for ovarian cancer (protocol stage)

Antiglucocorticoid and related treatments for psychosis (protocol stage)

Antihistamines as an adjunct to topical nasal steroids for intermittent and persistent allergic rhinitis in children (protocol stage)

Antihistamines for motion sickness (protocol stage)

Antihypertensive agents for preventing the progression of diabetic kidney disease (protocol stage)

Antihypertensive drugs for mild hypertension (protocol stage)

Antimicrobial agents for treating uncomplicated urinary tract infection in women (protocol stage)

Antioxidant micronutrients for lung disease in cystic fibrosis (protocol stage)

Antioxidant supplements for liver diseases (protocol stage)

Antioxidant vitamin supplementation for preventing and slowing the progression of age-related cataract (protocol stage)

Antioxidants for chronic kidney disease (protocol stage)

Antioxidants for female subfertility (protocol stage)

Antioxidants for male subfertility (protocol stage)

Antiplatelet agents for intermittent claudication (protocol stage)

Antipsychotic drugs for anorexia nervosa (protocol stage)

Antipsychotic medication for early episode schizophrenia (protocol stage)

Antipsychotic switching for people with schizophrenia who have neuroleptic-induced weight or metabolic problems (protocol stage)

Antiretroviral resistance testing in treatment-naive HIV-infected adults (protocol stage)

Antiretroviral therapy for infants with HIV infection (protocol stage)

Antithrombotic therapy for improving maternal or infant health outcomes in women considered at risk of placental dysfunction (protocol stage)

Antiviral agents for prophylaxis of herpesviridae infections in patients with haematological malignancies (protocol stage)

Antiviral agents for treating CMV infection of the nervous system in people with HIV (protocol stage)

Antiviral prophylactic intervention for hepatitis C virus in patients undergoing liver transplantation (protocol stage)

Antiviral prophylaxis for varicella zoster in immunocompromised patients (excluding haematological malignancies) (protocol stage)

Antiviral therapy for symptomatic congenital cytomegalovirus infection in neonates and infants up to 3 months of age (protocol stage)

Antiviral treatment for chronic hepatitis C in patients with human immunodeficiency virus (protocol stage)

Antiviral treatments for lamivudine-resistant chronic hepatitis B adult patients (protocol stage)

Antivirals for idiopathic sudden sensorineural hearing loss (protocol stage)

Appendix stump closure during laparoscopic appendectomy (protocol stage)

Aquatic therapy exercise for treating rheumatoid arthritis (protocol stage)

Aripiprazole alone or in combination for acute mania (protocol stage)

Aripiprazole for psychosis-induced aggression or agitation (protocol stage)

Aripiprazole versus placebo for schizophrenia (protocol stage)

Aromatase inhibitors for ovulation induction (protocol stage)

Aromatherapy for treatment of postoperative nausea and vomiting (protocol stage)

Arterial ligation versus embolisation for intractable posterior epistaxis (protocol stage)

Arthroscopic lavage for osteoarthritis of the knee (protocol stage)

Arthroscopy for temporomandibular disorders (protocol stage)

As required versus fixed schedule analgesic administration schedules for treating postoperative pain in children and adults (protocol stage)

Aspirin desensitisation therapy for aspirin-intolerant chronic rhinosinusitis (protocol stage)

Aspirin for primary prevention of coronary heart disease (protocol stage)

Aspirin with or without an antiemetic for acute migraine in adults (protocol stage)

Aspirin, steroidal and non-steroidal anti-inflammatory drugs for Alzheimer's disease (protocol stage)

Atherectomy for peripheral arterial disease (protocol stage)

Atomoxetine for attention deficit hyperactivity disorder in people with intellectual disabilities (protocol stage)

Atraumatic restorative treatment versus conventional restorative treatment for the management of dental caries (protocol stage)

Atypical Antipsychotics for Tourette's Syndrome (protocol stage)

Augmentation of psychotherapy with d-cycloserine for anxiety disorders (protocol stage)

Auricular acupuncture for opiate dependence in substance misuse treatment programmes (protocol stage)

Autologous platelet rich-plasma for treating chronic wounds (protocol stage)

Autologous stem cell transplantation vs chemotherapy in adult acute lymphocytic leukaemia (protocol stage)

Autologous versus prosthetic arteriovenous fistulae for vascular access (protocol stage)

Axillary staging for operable primary breast cancer. (protocol stage)

Azithromycin for treating uncomplicated malaria (protocol stage)

Azithromycin versus penicillin G Benzathine for early syphilis (protocol stage)

Azoles and ivermectin for treating strongyloides infection (protocol stage)