|
The Cochrane Collaboration
Cochrane Reviews |
| Explore | New + Updated | Other languages |
|
 |
Influenza vaccine for children and adults with bronchiectasisChang CC, Morris PS, Chang AB
Bookmark this:
     more ...
SummaryInfluenza vaccine for children and adults with bronchiectasisIn many countries, influenza vaccination is an accepted part of routine immunisation recommendations particularly in persons 65 years and over, those in long-term care facilities and also adults and children with chronic illnesses including those with bronchiectasis. In this review however, our search for randomised control trials examining the effectiveness of influenza vaccines for people with bronchiectasis revealed no relevant studies. In the absence of evidence, patients' needs should be individualised and national guidelines be adhered to.
This is a Cochrane review abstract and plain language summary, prepared and maintained by The Cochrane Collaboration, currently published in The Cochrane Database of Systematic Reviews 2010 Issue 1, Copyright © 2010 The Cochrane Collaboration. Published by John Wiley and Sons, Ltd.. The full text of the review is available in The Cochrane Library (ISSN 1464-780X).
This version first published online:
July 18. 2007 AbstractBackgroundBronchiectasis is a major cause of respiratory morbidity especially in developing countries. In affluent countries, bronchiectasis is increasingly recognised in certain subsections of communities (e.g. Aboriginal communities) as well as a coexistent disease/comorbidity and disease modifier in respiratory diseases such as COPD (reported rates of 29-50% in adults). Respiratory exacerbations in people with bronchiectasis are associated with reduced quality of life, accelerated pulmonary decline, hospitalisation and even death. Current recommendations for inactivated influenza vaccination includes adults aged 65 years and over, those in residential care and health care workers and also all adults and children with chronic illness, particularly cardiac and pulmonary diseases. ObjectivesTo evaluate the effectiveness of influenza vaccine as routine management in children and adults with bronchiectasis in (a) reducing the severity and frequency of respiratory exacerbations and (b) pulmonary decline Search strategyThe Cochrane Register of Controlled Trials (CENTRAL), the Cochrane Airways Group Specialised Register, MEDLINE and EMBASE databases were searched by the Cochrane Airways Group. Pharmaceutical manufacturers of influenza were also contacted. The latest searches were performed in July 2006. Selection criteriaAll randomised controlled trials with at least one annual influenza vaccine involving children or adults with bronchiectasis. Data collection and analysisResults of searches were reviewed against pre-determined criteria for inclusion. It was planned that two independent reviewers selected, extracted and assessed data for inclusion. Main resultsNo eligible trials were identified and thus no data were available for analysis. Authors' conclusionsThere is neither evidence for, nor against, routine annual influenza vaccination for children and adults with bronchiectasis. |