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Topical negative pressure (TNP) for partial thickness burnsWasiak J, Cleland H
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SummaryTopical negative pressure (TNP) for treating partial thickness burnsTopical negative pressure (TNP) therapy is the application of negative pressure across a wound to aid in wound healing. In this instance, the pressure is used to aid and drain excess fluid, reduce infection rates and increase localised blood flow, thereby supplying the burn wound with oxygen and nutrition to promote accelerated healing. Alternative names for TNP include vacuum-assisted closure (VAC) and sealed surface wound suction. There is a lack of evidence about whether TNP therapy is effective in treating people with partial thickness burns.
This is a Cochrane review abstract and plain language summary, prepared and maintained by The Cochrane Collaboration, currently published in The Cochrane Database of Systematic Reviews 2010 Issue 1, Copyright © 2010 The Cochrane Collaboration. Published by John Wiley and Sons, Ltd.. The full text of the review is available in The Cochrane Library (ISSN 1464-780X).
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July 18. 2007 AbstractBackgroundA burn wound is a complex and evolving injury, with both local and systemic consequences. Treatments include using a variety of dressings, but newer strategies such as topical negative pressure therapy (TNP) have been developed to try and promote the wound healing process and minimise burn wound progression. TNP uses a suction force to drain excess fluids. ObjectivesTo assess the effectiveness of TNP for those people with partial thickness burns. Search strategyWe searched the Cochrane Wounds Group Specialised Register (searched December 2008), the Cochrane Central Register of Controlled Trials (CENTRAL)(The Cochrane Library Issue 4, 2008), Ovid MEDLINE (1950 to November Week 3 2008), Ovid EMBASE (1980 to 2008 Week 49) and EBSCO CINAHL (1982 to December Week 1 2008). Selection criteriaAll randomised controlled trials (RCTs) and controlled clinical trials (CCTs) that evaluated the safety and effectiveness of TNP for partial thickness burns. Data collection and analysisTwo authors using standardised forms extracted the data independently. We assessed each trial for internal validity, and resolved differences by discussion. Main resultsOne RCT satisfied the inclusion criteria. We undertook a narrative synthesis of results as the absence of missing data, poor reporting, or both, precluded us from carrying out any formal statistical analysis. The methodological quality of the trial was poor. Authors' conclusionsThere is a paucity of high quality RCTs on TNP for partial thickness burn injury with insufficient sample size and adequate power to detect differences, if there are any, between TNP and conventional burn wound therapy dressings. |