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Glucocorticoids for acute viral bronchiolitis in infants and young childrenPatel H, Platt R, Lozano JM
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SummarySystemic glucocorticoids do not appear to have a clinically significant effect on the course of acute viral bronchiolitis in infants and young childrenSystemic glucocorticoids (for example prednisone), have known anti-inflammatory effects, and have been used in young children with acute viral bronchiolitis for over 40 years. A meta-analysis found 13 studies involving 1,198 affected children. No benefits from glucocorticoids were found for either length of hospital stay or clinical score. Neither were benefits found for other outcomes. Systemic glucocorticoids do not provide clinical benefit for infants and young children with acute viral bronchiolitis.
This is a Cochrane review abstract and plain language summary, prepared and maintained by The Cochrane Collaboration, currently published in The Cochrane Database of Systematic Reviews 2009 Issue 4, Copyright © 2009 The Cochrane Collaboration. Published by John Wiley and Sons, Ltd.. The full text of the review is available in The Cochrane Library (ISSN 1464-780X). |