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Anticholinergic therapy for bronchiectasisLasserson TJ, Holt K, Evans DJ, Milan SJ, Greenstone M
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SummaryThe effects of anticholinergic drugs in the treatment of bronchiectasisThere is no evidence for or against the use of anticholinergic drugs such as Atrovent in the treatment of bronchiectasis.
This is a Cochrane review abstract and plain language summary, prepared and maintained by The Cochrane Collaboration, currently published in The Cochrane Database of Systematic Reviews 2010 Issue 1, Copyright © 2010 The Cochrane Collaboration. Published by John Wiley and Sons, Ltd.. The full text of the review is available in The Cochrane Library (ISSN 1464-780X).
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October 23. 2001 AbstractBackgroundAnticholinergic agents block bronchoconstriction mediated by the vagus nerve and may also dry up bronchial secretions. They are effective in obstructive airways disease and may be beneficial in bronchiectasis ObjectivesTo determine the effect of anticholinergic therapy in acute exacerbations and stable bronchiectasis. Search strategyThe Cochrane Airways Group Specialised Register was searched and bibliographies of retrieved papers were checked. Searches are current as of May 2007. Selection criteriaOnly randomised controlled trials were considered. Data collection and analysisTwo reviewers assessed the retrieved studies working independently. Main resultsTwelve studies were identified, of which six were obtained for further scrutiny. One was translated from Italian. None met the inclusion criteria. An update search conducted in May 2005 did not yield any new studies. Authors' conclusionsNo formal recommendations can be made about the use of anticholinergic therapy in acute or stable bronchiectasis based on the literature currently available. |