<< Cochrane Influenza Resources
The Cochrane Reviews listed below have summarized data about the benefits and harms of several interventions for preventing and treating influenza. These comprehensive reviews provide valuable information for patients, doctors, and healthcare decision-makers about what steps to take or interventions to use to prevent influenza or aid its treatment.
Prevention: hand washing and other physical methods | amantadine (Symmetrel or Symadine) – children, adults, elderly | rimantadine (Flumadine) – children, adults, elderly | zanamivir (commonly known as Relenza) – children, adults | oseltamivir (commonly known as Tamiflu) | vaccines for healthy people – children, adults, elderly, healthcare workers | vaccines for people with other illnesses – asthma, bronchiectasis, chronic obstructive pulmonary disease, cystic fibrosis, children with cancer | Chinese medicinal herbs
Treatment: amantadine (Symmetrel or Symadine) – children, adults, elderly | rimantadine (Flumadine) – children, adults, elderly | zanamivir (commonly known as Relenza) – children, adults | oseltamivir (commonly known as Tamiflu) | Chinese medicinal herbs | fluids
Preventing influenza
Physical methods, including hand washing, masks, and gloves |
Interventions for the interruption or reduction of the spread of respiratory viruses
A review of hand washing and other methods to stop or reduce the spread of respiratory viruses, including the influenza vaccine |
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Drugs, including neuraminidase inhibitors (commonly known as Relenza and Tamiflu) |
Amantadine and rimantadine for influenza A in children and the elderly
A review of amantadine (commonly known as Symmetrel or Symadine) and rimantadine (commonly known as Flumadine) to prevent and treat influenza in two vulnerable age groups – children and the elderly |
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Amantadine and rimantadine for influenza A in healthy adults
A review of amantadine (commonly known as Symmetrel) and rimantadine (commonly known as Flumadine) to prevent and treat influenza in healthy adults |
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Neuraminidase inhibitors for preventing and treating influenza in children
A review of zanamivir and oseltamivir, two neuraminidase inhibitors commonly known as Relenza and Tamiflu, to prevent and treat influenza in children |
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HTML (full text)
Español (PDF)
Deutsch (Laienverständliche Zusammenfassung)
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Neuraminidase inhibitors for preventing and treating influenza in healthy adults
A review of zanamivir and oseltamivir, two neuraminidase inhibitors commonly known as Relenza and Tamiflu, to prevent and treat influenza in healthy adults |
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Deutsch (Laienverständliche Zusammenfassung)
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Vaccines for healthy people |
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Vaccines for preventing influenza in children
A review of vaccines for preventing influenza in children. Children, along with people over the age of 65 years, are at a greater risk of complications from influenza |
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Vaccines for preventing influenza in healthy adults
A review of the different types of influenza vaccines for healthy adults
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Vaccines for preventing influenza in the elderly
A review of vaccines for preventing influenza in children. People over the age of 65, along with children, are at a greater risk of complications from influenza
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Influenza vaccination for health care workers who work with the elderly
Healthcare workers have substantial rates of clinical and sub-clinical influenza during influenza seasons and may transmit influenza to those in their care, especially the elderly. This review looks at the benefits and harms of vaccinating healthcare workers against influenza |
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Vaccines for people with other illnesses |
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Vaccines for preventing influenza in people with asthma
People with asthma may benefit from an influenza vaccine since influenza may exacerbate asthma, but the vaccine may adversely affect lung function. This review examines the evidence on the benefits and harms of using influenza vaccines in people with asthma |
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Influenza vaccine for children and adults with bronchiectasis
A review of the benefits and harms of the influenza vaccine for people with bronchiectasis, an obstructive lung disease that causes productive or wet cough, shortness of breath on exertion, and presence of other respiratory signs |
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Influenza vaccine for patients with chronic obstructive pulmonary disease
Influenza infection causes excess morbidity and mortality in people with chronic obstructive pulmonary disease, but there is also the potential for influenza vaccination to cause adverse effects or not to be cost effective. This review looks at the benefits and harms of the influenza vaccine for people with chronic obstructive pulmonary disease |
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Vaccines for preventing influenza in people with cystic fibrosis
Viral respiratory tract infections in people with cystic fibrosis have a deteriorating effect on their lung function and disease progression, and annual influenza vaccination is therefore commonly recommended for people with cystic fibrosis. This review looks at the effectiveness of influenza vaccines for people with cystic fibrosis
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Influenza vaccination in children being treated with chemotherapy for cancer
Influenza infection is a potential cause of severe morbidity in children with cancer. This review looks at the benefits and harms of influenza vaccination since there are conflicting data concerning the immune response to influenza vaccination in children with cancer
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Treating influenza
Drugs, including neuraminidase inhibitors (commonly know as Relenza and Tamiflu) |
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Amantadine and rimantadine for influenza A in children and the elderly
A review of amantadine (commonly known as Symmetrel or Symadine) and rimantadine (commonly known as Flumadine) to prevent and treat influenza in two vulnerable age groups – children and the elderly
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PDF (free to access)
HTML (full text)
Español (PDF)
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Amantadine and rimantadine for influenza A in healthy adults
A review of amantadine (commonly known as Symmetrel) and rimantadine (commonly known as Flumadine) to prevent and treat influenza in healthy adults
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PDF (free to access)
HTML (full text)
Español (PDF)
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Neuraminidase inhibitors for preventing and treating influenza in children
A review of zanamivir and oseltamivir, two neuraminidase inhibitors commonly known as Relenza and Tamiflu, to prevent and treat influenza in children
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PDF (free to access)
HTML (full text)
Español (PDF)
Deutsch (Laienverständliche Zusammenfassung)
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Neuraminidase inhibitors for preventing and treating influenza in healthy adults
A review of zanamivir and oseltamivir, two neuraminidase inhibitors commonly known as Relenza and Tamiflu, to prevent and treat influenza in healthy adults
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PDF (free to access)
HTML (full text)
Español (PDF)
Deutsch (Laienverständliche Zusammenfassung)
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Chinese medicinal herbs |
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Chinese medicinal herbs for influenza
A review of Chinese medicinal herbs (including natural herbs and herbal products extracted from natural herbs) for preventing and treating influenza
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Español (PDF)
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Drinking extra fluids |
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Advising patients to increase fluid intake for treating acute respiratory infections
A review about the benefits and harms of increased fluid intake as a treatment for acute respiratory infections
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