Evidence summaries for topics of high priority in health care in affected regions.

Prevention of malaria

Does prophylaxis or intermittent treatment with antimalarial drugs benefit young children living in areas with malaria? (PDF document 0.15 MB)

Do pre-erythrocyte vaccines prevent malaria illness and infection? (PDF document 0.14 MB)

Do vaccines targeting the blood stage of the malaria parasite prevent malaria illness and infection? (PDF document 0.13 MB)

Drugs for preventing malaria-related illness in pregnant women and death in the newborn (PDF document 0.22 MB)

Insecticide-treated bed nets and curtains for preventing malaria (PDF document 0.25 MB)

Should people with sickle cell disease living in malaria-endemic areas take malaria drug prophylaxis continuously? (PDF document 0.16 MB)

Should pregnant women living in malarial areas use insecticide-treated nets? (PDF document 0.17 MB)

Treatment of malaria

Amodiaquine for treating malaria (PDF document 0.40 MB)

Artemether-lumefantrine (six-dose regimen) for treating uncomplicated falciparum malaria (A summary for this topic is not currently available. The relevant Cochrane review is available here.)

Artesunate plus mefloquine versus mefloquine for treating uncomplicated malaria (A summary for this topic is not currently available. The relevant Cochrane review is available here.)

Atovaquone-proguanil for treating uncomplicated malaria (A summary for this topic is not currently available. The relevant Cochrane review is available here.)

Chloroquine or amodiaquine combined with sulfadoxine-pyrimethamine for treating uncomplicated malaria (A summary for this topic is not currently available. The relevant Cochrane review is available here.)

Chlorproguanil-dapsone for treating uncomplicated malaria  (PDF document 0.18 MB)

Does primaquine prevent relapses in people with Plasmodium viva malaria? (PDF document 0.17 MB)

Drugs for treating uncomplicated malaria in pregnant women (PDF document 0.12 MB)

High first dose quinine regimen for treating severe malaria (PDF document 0.14 MB)

Intramuscular arteether for treating severe malaria (PDF document 0.14 MB)

Iron chelating agents for treating malaria (A summary for this topic is not currently available. The relevant Cochrane review is available here.)

Is intrarectal quinine as effective as other administration routes in people with malaria? (PDF document .24 MB)

Mannitol and other osmotic diuretics as adjuncts for treating cerebral malaria (PDF document 0.11 MB)

Routine anticonvulsants for treating cerebral malaria (PDF document 0.20 MB)

Steroids for treating cerebral malaria (PDF document 0.17 MB)

Unit-dose packaged drugs for treating malaria (PDF document 0.12 MB)

Information on this topic is also available in Clinical Evidence; click here for information on severe life-threatening malaria and malaria in travellers.

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