Radiation therapy for preventing instrumentation track metastases in malignant pleural mesothelioma

To assess the effects of radiation therapy for preventing instrumentation track metastases in malignant pleural mesothelioma.

Secondary objectives include to determine:

  • the true incidence of instrumentation track metastases in contemporary MPM patient populations;
  • the impact of patient characteristics (e.g. histological subtype of MPM) and intervention characteristics (e.g. maximally invasive versus minimally invasive) on the risk of developing instrumentation track metastases;
  • the impact of radiation treatment on secondary patient outcomes such as quality of life, survival time, and disease-free interval; and
  • the incidence of irradiation-induced dermatitis in MPM patients receiving prophylactic radiotherapy.

This is a protocol.