Interventions for the prevention of acute postoperative pain in adults following brain surgery

The objectives of this review are:

  1. to determine the effectiveness of pharmacological interventions for the prevention of acute postoperative pain in adult participants undergoing brain surgery;
  2. to determine how the evaluated interventions compare in terms of other clinically important outcomes including, sedative effects, additional analgesic requirements, incidence of chronic headache, length of hospital stay and adverse events;
  3. to examine whether the above characteristics are significantly different for certain subgroups as defined below;
  4. to make appropriate clinical and future research recommendations based on the evaluated evidence.

This is a protocol.

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