In non-intubated preterm infants with, or at risk of, RDS to compare surfactant administration via brief tracheal catheterization with:
- continuation of non-invasive respiratory support (CPAP) or high flow nasal cannulae (HFNC) without surfactant administration;
- intubation and surfactant administration through an ETT with or without intent to remove the ETT immediately after the procedure;
- to compare different methods of surfactant administration via brief tracheal catheterization with each other.
This is a protocol.