Surfactant therapy via brief tracheal catheterization in preterm infants with or at risk of respiratory distress syndrome

In non-intubated preterm infants with, or at risk of, RDS to compare surfactant administration via brief tracheal catheterization with:

  1. continuation of non-invasive respiratory support (CPAP) or high flow nasal cannulae (HFNC) without surfactant administration;
  2. intubation and surfactant administration through an ETT with or without intent to remove the ETT immediately after the procedure;

Additionally:

  • to compare different methods of surfactant administration via brief tracheal catheterization with each other.

This is a protocol.

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