Blood pressure lowering efficacy of calcium channel blockers for primary hypertension

Primary objective:
To quantify the dose-related effects of various doses and types of calcium channel blockers on systolic and diastolic blood pressure versus placebo in patients with primary hypertension.

Secondary objectives:
1. To determine the effects of calcium channel blockers on variability of blood pressure.
2. To determine the effects of calcium channel blockers on pulse pressure.
3. To quantify the dose-related effects of calcium channel blockers on heart rate.
4. To quantify the effects of calcium channel blockers in different doses on withdrawals due to adverse events.

This is a protocol.

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