Continuous versus interrupted stitches for closing the skin after non-childbirth surgery |
Continuous versus pulsatile oxytocin administration for the augmentation of labour |
Contraception decision aids to improve care and effective method use |
Contraception interventions for women seeking abortion |
Contraceptive pills and venous thrombosis |
Contracting out to improve the use of clinical health services and health outcomes in low- and middle-income countries |
Contracts between patients and healthcare practitioners for improving patients' adherence to recommended healthcare activities |
Contrast-enhanced ultrasound compared with computed tomography, magnetic resonance imaging, and positron emission tomography-computed tomography for diagnosing liver metastases in people with newly diagnosed colorectal cancer |
Contribution types and membership points |
Control interventions for preventing spread of vancomycin-resistant enterococci (VRE) in hospitals |
Control interventions in randomised trials for people with a mental health disorder |
Control interventions in randomised trials for people with a mental health disorder |
Control methods for and |
Controlled hypotension versus normotensive resuscitation strategy for people with ruptured abdominal aortic aneurysm |
Controlled ovarian stimulation protocols for assisted reproduction: a network meta-analysis |
Controlled studies for treatment of dysarthia associated with acquired brain injury in childhood urgently required |
Controlling blood glucose in treating diabetic foot ulcers (sores) |
Controlling high blood sugar levels with insulin in people who have had an acute ischaemic stroke |
Convalescent plasma and hyperimmune immunoglobulin to prevent infection with SARS-CoV-2 |
Convective radiofrequency water vapour thermal therapy for lower urinary tract symptoms in men with benign prostatic hyperplasia |
Conventional (traditional) chest physiotherapy compared to other methods of airway clearance in people with cystic fibrosis |
Conventional surgical hemorrhoidectomy results in fewer recurrences than stapled hemorrhoidopexy. |
Conversion of calcineurin inhibitor treatment to target of rapamycin inhibitor treatment versus continuation of calcineurin inhibitor treatment for liver transplant recipients |
Cooling for newborns with hypoxic ischaemic encephalopathy |
Cooling plus inhaled xenon for newborns with hypoxic-ischaemic encephalopathy |
Cooling the body after resuscitation following cardiac arrest |
Cooling the body after resuscitation following cardiac arrest |
Cooling the brain during surgery to prevent death or severe disability in people with brain aneurysms |
Cooling therapy for acute stroke |
Cooling therapy for acute stroke |
Coordination of care to improve outcomes of emergency medical services |
Copper IUDs versus long-acting hormone injections and implants for contraception |
Cord traction to deliver the afterbirth |
Cordyceps sinensis (a Chinese medicinal herb) for treating chronic kidney disease |
Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients |
Cordyceps sinensis for hypertension in adults |
Coriolus versicolor mushroom in colorectal cancer |
Corneal collagen cross-linking for infectious keratitis |
Corneal collagen cross-linking for thinning of the transparent front part of the eye ('keratoconus') |
Corneal confocal microscopy for the diagnosis of diabetic sensorimotor polyneuropathy in people with type 1 and 2 diabetes mellitus |
Coronary artery bypass grafting surgery versus percutaneous coronary intervention for coronary artery disease |
Coronary artery bypass surgery performed with versus without cardiac arrest and cardiopulmonary bypass in patients with ischaemic heart disease |
Coronary artery bypass surgery versus medical therapy alone for ischaemic heart disease |
Coronavirus (COVID-19) - Cochrane resources and news |
Coronavirus (COVID-19) - Cochrane resources and news |
Coronavirus (COVID-19): Special Collections |
Cortical and deep brain stimulation for functional recovery and reducing complications after stroke |
Corticosteroid eye drops used in addition to standard antibiotic therapy in the treatment of bacterial keratitis |
Corticosteroid injection for de Quervain's tenosynovitis |
Corticosteroid injections for shoulder pain |
Corticosteroid injections for treatment of sciatica |
Corticosteroid regimens for treatment of acute and chronic graft versus host disease (GvHD) after allogenic stem cell transplantation |
Corticosteroid therapy for children with nephrotic syndrome |
Corticosteroid therapy for Duchenne muscular dystrophy |
Corticosteroids as stand-alone or add-on treatment for sore throat |
Corticosteroids for acute ischaemic stroke |
Corticosteroids for acute severe asthma in hospitalised patients |
Corticosteroids for aneurysmal subarachnoid haemorrhage and primary intracerebral haemorrhage |
Corticosteroids for bacterial meningitis |
Corticosteroids for Bell's palsy |
Corticosteroids for cervical ripening and induction of labour |
Corticosteroids for children with septic arthritis |
Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy |
Corticosteroids for Guillain-Barré syndrome |
Corticosteroids for HELLP syndrome in pregnancy |
Corticosteroids for HELLP syndrome in pregnancy |
Corticosteroids for hospitalised children with acute asthma |
Corticosteroids for induction of remission in Crohn's disease |
Corticosteroids for maintenance of remission in Crohn's disease |
Corticosteroids for managing people with tuberculous meningitis |
Corticosteroids for myasthenia gravis |
Corticosteroids for periorbital and orbital cellulitis |
Corticosteroids for preventing complications following facial plastic surgery |
Corticosteroids for preventing graft-versus-host disease after allogeneic myeloablative stem cell transplantation |
Corticosteroids for preventing relapse following acute exacerbations of asthma |
Corticosteroids for preventing serious breathing problems in the newborn after caesarean section at term |
Corticosteroids for pulmonary sarcoidosis |
Corticosteroids for the management of cancer pain in adults |
Corticosteroids for the management of cancer-related breathlessness in adults with cancer |
Corticosteroids for the management of nausea and vomiting not related to chemotherapy, radiotherapy, or surgery in adult cancer patients |
Corticosteroids for the resolution of malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer |
Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis) |
Corticosteroids for the treatment of parasitic eosinophilic meningitis |
Corticosteroids for toxoplasma infection in the eye |
Corticosteroids for treating cerebral malaria |
Corticosteroids for treating dengue infection in children and adults |
Corticosteroids for treating hypotension in preterm infants |
Corticosteroids for treating nerve damage in leprosy |
Corticosteroids for treating optic neuritis |
Corticosteroids for treating oral lichen planus |
Corticosteroids for treating sepsis |
Corticosteroids for treatment of leptospirosis |
Corticosteroids including ACTH (adrenocorticotrophin hormone) for childhood epilepsy other than epileptic spasms |
Corticosteroids to treat brain injury |
Corticosteroids used in addition to antiviral drugs in patients with Ramsay Hunt syndrome |
Corticosteroids versus placebo and NSAIDs for rheumatoid arthritis |
Cot-nursing versus incubator care for preterm infants |
Counselling and education interventions for promoting adherence to treatment for tuberculosis |
Counselling for mental health and psychosocial problems in primary care |
Counting down to Cochrane’s first ever Virtual Colloquium #CochraneSantiago - how you can join! |
Couple and family therapies for post-traumatic stress disorder (PTSD) |
Couple therapy for depression |
Couple-based interventions for improving dyadic adjustment in people with cancer and their spousal partners |
Covering ileo- or colostomy in anterior resection for rectal carcinoma is associated with less anastomotic leakage, but does not offer advantage in term of 30 days or long term mortality. |
COVID-19 and its cardiovascular effects: a systematic review of prevalence studies |
COVID-19 Rapid Review - Video calls for reducing social isolation and loneliness in older people |
COVID-19 Recommendations Map: Turning evidence into policy and practice |
COVID-19 Special Collection: evidence relevant to clinical rehabilitation |
COVID-19 Study Register: Cochrane’s curated collection for global researchers passes more than 20,000 references...and counting! |
COVID-19 vaccination for people with autoimmune inflammatory rheumatic diseases on immunomodulatory therapies |
COVID-19: Interventions to reduce the risk of coronavirus infection among workers outside healthcare settings |
COVID-19: Making sense of health information |
Covidence continues improvements to streamline Cochrane Reviews |
COVID‐19: working together and making a difference for decision‐makers |
Cox-2 Inhibitors in the Prevention of Melanoma |
Cradle hold versus alternate positions for bottle feeding preterm infants |
Cranberries for preventing urinary tract infections |
Cranberries for preventing urinary tract infections |
Cranberries for preventing urinary tract infections |
Cranberries for preventing urinary tract infections |
Cranberries for treating asymptomatic bacteriuria during pregnancy |
Creams, lotions and gels (topical treatments) for fungal infections of the skin and nails of the foot |
Creatine for amyotrophic lateral sclerosis/motor neuron disease |
Creatine for Parkinson's disease |
Creatine for treating muscle disorders |
Creatine for women in pregnancy for neuroprotection of the fetus |
Crisis intervention for people with severe mental illnesses |
Crisis interventions for people with borderline personality disorder |
Critical incident audit and feedback to improve perinatal and maternal mortality and morbidity |
Cromolyn sodium for the prevention of chronic lung disease in preterm infants |
Cryoablation versus radiofrequency catheter ablation for AV nodal re-entrant tachycardia |
Cryoplasty for peripheral vascular disease |
Cryotherapy for acute non-specific neck pain |
Cryotherapy for liver metastases |
Cuffed versus uncuffed endotracheal tubes for neonates |
Cuffed versus uncuffed tubes in children aged eight years and under, having general anaesthetic |
Cultural competence education for health professionals |
Culturally appropriate health education for people in ethnic minority groups with type 2 diabetes mellitus |
Culture media for human pre-implantation embryos for in assisted reproductive technology cycles |
Culture-specific programs for children and adults from minority groups who have asthma |
Cultured epithelial autograft in the treatment of acute burn wounds |
Cup feeding versus other forms of supplemental enteral feeding for newborn infants unable to fully breastfeed |
Curative surgery for obstruction from primary left colorectal carcinoma: Primary or staged resection? |
Curcuma longa (turmeric) or its active ingredients for osteoarthritis |
Curcumin for maintenance of remission in ulcerative colitis |
Curettage versus other methods of adenoidectomy in children |
Currently available malaria vaccines are not yet sufficiently effective, but new vaccines show promise in early tests. |
Currently not enough evidence that using cisplatin, a chemotherapy (anti-cancer) drug, before other treatments improves the survival of people with advanced bladder cancer |
Currently there is no clear evidence that cholesterol drugs reduce melanoma risk. |
Currently there is no evidence available from randomised control trials to determine whether Single Incision Laparoscopic Surgery provides any better effect than Conventional Multi-incision Laparoscopic Surgery for appendicectomy. |
Currently there is no evidence to support the routine use of corticosteroids alone in the management of idiopathic pulmonary fibrosis. |
Currently there is not enough evidence to conclude that psychosocial treatments alone are adequate to treat people with opiate abuse and dependence. |
Custom-made foot orthoses for the treatment of foot pain |
Customised versus population-based growth charts as a screening tool for detecting small for gestational age infants in low-risk pregnant women |
Cutaneous antisepsis for prevention of intravascular catheter–associated infection in newborn infants |
Cutting back on sugar-sweetened beverages: What works? |
Cutting down or changing the fat we eat may reduce our risk of heart disease |
Cyanoacrylate microbial sealants for skin preparation prior to surgery |
Cycle regimens for frozen-thawed embryo transfer |
Cycled light in the intensive care unit for preterm and low birth weight infants |
Cyclin-dependent kinase (CDK) inhibitors for hormone receptor-positive advanced breast cancer |
Cycling infrastructure (changes to the road environment) for reducing cycling injuries in cyclists |
Cyclo-oxygenase (COX) inhibitors for preventing labour before full-term pregnancy |
Cyclo-oxygenase (COX) inhibitors for threatened miscarriage |
Cyclo-oxygenase (COX) inhibitors for treating preterm labour |
Cyclobenzaprine drug treatment for myofascial pain in adults |
Cyclofenil is a drug that has been studied in the treatment for Raynaud's phenomenon and associated conditions. It is not used for RP and is an anabolic steroid. See also Cochrane review on Stanazol which is also an anabolic steroid. |
Cyclophosphamide compared to ifosfamide for the treatment of sarcoma in children and young adults |
Cyclophosphamide for interstitial lung disease associated with connective tissue disease |
Cyclophosphamide for treating rheumatoid arthritis |
Cyclophosphamide versus methylprednisolone for lupus |
Cyclosporin (the drug for preventing organ rejection after transplant) as an oral corticosteroid sparing agent in stable asthma |
Cyclosporin A was without significant effects on mortality, liver transplantation, or progression of primary biliary cirrhosis, and patients given cyclosporin A experienced more adverse events |
Cyclosporine A eye drops for the treatment of dry eye |
Cyclosporine A for induction of remission in severe ulcerative colitis |
Cyclosporine for maintenance of remission in Crohn's disease |
Cyclosporine for treating rheumatoid arthritis |
Cyclosporine for treatment of active Crohn's disease |
Cyproterone acetate appears to be as effective as other medications for hirsutism in women caused by excessive androgen production by the ovaries |
Cysteine, cystine or N-acetylcysteine supplementation in parenterally fed neonates |
Cytology for the diagnosis of endometrial cancer in symptomatic women |
Cytoreductive surgery alone or combined with hyperthermic intraperitoneal chemotherapy (HIPEC) for pseudomyxoma peritonei |
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal metastases in patients with colorectal cancer |
Czech Republic to host Global Evidence Summit 2021 |
D-dimer for excluding pulmonary embolism in hospital outpatient and accident and emergency populations |
D-Dimer tests for the diagnosis of deep venous thrombosis in symptomatic hospital outpatients with a clinical prediction rule |
D-mannose (sugar tablets) for preventing or treating urinary tract infections in adults and children |
D-penicillamine did not reduce the risk of mortality of patients with primary biliary cirrhosis but increased the occurrences of adverse events |
D-Penicillamine for preventing retinopathy of prematurity in preterm infants |
Daclizumab, an antibody, as possible alternative therapy to interferon beta in people with relapsing remitting multiple sclerosis |
Daily intake of 1 gr dietary calcium may have moderate protective effect on development of colorectal adenomatous polyps |
Daily iron supplementation for prevention or treatment of iron deficiency anaemia in infants, children, and adolescents |
Dan Shen agents for acute ischaemic stroke |
Danazol for pelvic pain associated with endometriosis |
Danazol for treating subfertility |
Danazol for treatment of women with symptoms caused by uterine fibroids |
Danazol is an effective treatment for the reduction of heavy menstrual bleeding, but the adverse effects may be unacceptable to women |
Dance therapy for schizophrenia |
Dance/movement therapy for cancer patients |
Danshen (Chinese medicinal herb) preparations for acute myocardial infarction |
Dapagliflozin for adults with type 2 diabetes mellitus |
Dapsone as an oral corticosteroid sparing agent for asthma |
Darbepoetin alfa to treat anaemia in people with chronic kidney disease |
David Sackett Prize awarded to Sir Iain Chalmers |
Day 5 versus day 3 embryo biopsy for genetic testing for single gene disorders before embryo implantation |
Day care for pre-school children |
Day centres for severe mental illness |
Day hospital versus admission for acute psychiatric disorders |
Day hospital versus outpatient care for people with schizophrenia |
Day three versus day two embryo transfer following in vitro fertilisation or intracytoplasmic sperm injection |
Day-surgery versus overnight stay surgery for laparoscopic cholecystectomy |
De novo mTOR inhibitor immunosuppression versus calcineurin inhibitor immunosuppression for liver transplant recipients |
De-escalation of dual antiplatelet therapy for patients with acute coronary syndrome after percutaneous coronary intervention: a network meta-analysis of randomised controlled trials |
De-escalation techniques for psychosis-induced aggression or agitation |
Deadline extended for expressions of interest to host Global Evidence Summit, 2021 |
Deadline extended to 6 March - Cochrane London 2023: Call for abstracts |
Deadline extended: the 2021 Cochrane-REWARD prize for reducing waste in research |
Debridement for venous leg ulcers |
Debridement of the nasal and sinus cavities in the postoperative care of patients who have had endoscopic sinus surgery for rhinosinusitis |
Debriefing interventions for the prevention of psychological trauma in women following childbirth |
Debulking hysterectomy followed by chemoradiotherapy versus chemoradiotherapy for FIGO (2019) stage IB3/II cervical cancer |
Decentralised versus centralised governance of health services |
Decision aids for people deciding about taking part in clinical trials |
Decision aids for people facing health treatment or screening decisions |
Decision aids for the management of menopausal symptoms |
Decision coaching for people making healthcare decisions |
Decompressive surgery for treating nerve damage in leprosy |
Decongestants and antihistamines for acute otitis media in children |
Decongestants, antihistamines and nasal irrigation for acute sinusitis in children |
Decontamination of environmental surfaces in hospitals to reduce hospital acquired infections |
Deep anterior lamellar keratoplasty versus penetrating keratoplasty for treating keratoconus |
Deep brain stimulation for people with involuntary posturing, or dystonia |
Deep transverse friction massage for the treatment of lateral elbow or lateral knee tendinitis |
Deep versus shallow suction of endotracheal tubes in ventilated neonates and young infants |
Deferasirox for managing iron overload in people with myelodysplastic syndrome |
Deferasirox for managing iron overload in people with thalassaemia |
Deferasirox for managing transfusional iron overload in people with sickle cell disease |
Defining Cochrane’s success |
Definitions and reporting of hypoglycaemia in trials of long-acting insulin analogues in people with type 1 diabetes mellitus |
Deflation of gastric band balloon in pregnancy for improving outcomes |
Degarelix for newly diagnosed advanced prostate cancer |
Dehumidifiers in the home for asthma |
Dehydroepiandrosterone (DHEA) for lupus erythematosus |
Dehydroepiandrosterone for women in the peri- or postmenopausal phase |
Delayed antibiotic prescriptions for respiratory tract infections |
Delayed antibiotic prescriptions for respiratory tract infections |
Delayed initiation or reduced initial dose of calcineurin-inhibitors for kidney transplant recipients |
Delayed introduction of progressive enteral feeds to prevent necrotising enterocolitis in very low birth weight infants |
Deliberate hypotension for orthopaedic surgery |
Delivering clot-busting therapy before reaching hospital or in hospital to help people who are having heart attacks |